[en] To address the question of whether the increased plasma concentration of interleukin 6 (IL-6) following strenuous muscular work could be related to exercise-induced muscle damage, 5 moderately active male volunteers underwent two isokinetic exercise sessions in the eccentric mode, separated by a period of 3 weeks during which the subjects underwent five training sessions. Before training, exercise was followed by severe muscle pain (delayed-onset muscle soreness; DOMS), and by significant increases in plasma IL-6 level and serum myoglobin concentration (SMb) (P < 0.001). After training, postexercise DOMS and SMb values were significantly lower than those measured before training. There was no significant difference between plasma IL-6 levels measured at the same time points before and after training. We conclude that the hypothetical relationship between exercise-induced muscle damage and increased postexercise levels of circulating IL-6 is not substantiated by the present results.
Disciplines :
Human health sciences: Multidisciplinary, general & others Anesthesia & intensive care
Author, co-author :
Croisier, Jean-Louis ; Université de Liège - ULiège > Département des sciences de la motricité > Kinésithérapie générale et réadaptation
Camus, Gérard; Université de Liège - ULiège
Venneman, Ingrid ; Centre Hospitalier Universitaire de Liège - CHU > Anesthésie et réanimation
Dupont, Ginette ; Université de Liège - ULiège > Centre de l'oxygène : Recherche et développement (C.O.R.D.)
Juchmes-Ferir, A.
Lamy, Maurice ; Université de Liège - ULiège > Département des sciences cliniques > Anesthésie et réanimation
Crielaard, Jean-Michel ; Université de Liège - ULiège > Département des sciences de la motricité > Evaluation et entraînement des aptitudes physiques
Deby, Carol ; Centre Hospitalier Universitaire de Liège - CHU > Administration des patients - Admission des hospitalisés
Duchateau, J.
Language :
English
Title :
Effects of Training on Exercise-Induced Muscle Damage and Interleukin 6 Production
Publication date :
February 1999
Journal title :
Muscle and Nerve
ISSN :
0148-639X
eISSN :
1097-4598
Publisher :
Wiley Periodicals, New York, United States - New York
scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.
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