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Myoglobinurie atypique chez les chevaux au pré: une série de cas en Belgique
Delguste, Catherine
2002
 

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Keywords :
atypical myopathy; myoglobinuria; horses
Abstract :
[en] Atypical myoglobinuria in grazing horses was described in United Kingdom and Germany between 1984 and 1996. Fourteen horses were presented at the University of Liège between November 2000 and April 2001, with a clinical history suggesting atypical myoglobinuria. Lesions were similar to those previously described. All horses were at rest and grazing when they developed clinical signs. Three times, the syndrome killed several horses grazing together. Horses were generally found recumbent, nearly or totally unable to stand up. They were presenting tachycardia, polypnoea and myoglobinuria, and died rapidly. When performed, blood analysis revealed severe muscular enzymatic activity rises. Histopathology revealed pulmonary congestion and oedema, and squeletal muscular fibers degeneration, mostly in respiratory and postural muscles. These observations are in accordance with cases of atypical myoglobinuria previously described in UK and Germany. The aetiology of this pathology is still unknown, despite of research attempts. An epidemiological inquiry protocol was developed in order to investigate upcoming cases within the scope of aetiologic research. Atypical myoglobinuria in grazing horses was described in United Kingdom and Germany between 1984 and 1996. Fourteen horses were presented at the University of Liège between November 2000 and April 2001, with a clinical history suggesting atypical myoglobinuria. Lesions were similar to those previously described. All horses were at rest and grazing when they developed clinical signs. Three times, the syndrome killed several horses grazing together. Horses were generally found recumbent, nearly or totally unable to stand up. They were presenting tachycardia, polypnoea and myoglobinuria, and died rapidly. When performed, blood analysis revealed severe muscular enzymatic activity rises. Histopathology revealed pulmonary congestion and oedema, and squeletal muscular fibers degeneration, mostly in respiratory and postural muscles. These observations are in accordance with cases of atypical myoglobinuria previously described in UK and Germany. The aetiology of this pathology is still unknown, despite of research attempts. An epidemiological inquiry protocol was developed in order to investigate upcoming cases within the scope of aetiologic research.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Delguste, Catherine ;  Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Département clinique des animaux de compagnie et des équidés
Language :
French
Title :
Myoglobinurie atypique chez les chevaux au pré: une série de cas en Belgique
Alternative titles :
[en] Atypical myoglobinuria in grazing horses: an outbreak in Belgium
Defense date :
September 2002
Institution :
ULiège - Université de Liège
Degree :
diplôme d'études approfondies en sciences vétérinaires
Promotor :
Amory, Hélène ;  Université de Liège - ULiège > Département d'Enseignement et de Clinique des Equidés (DCE) > Médecine interne des équidés
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since 24 June 2011

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