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New perspectives in the management of osteoarthritis. Structure modification: Facts or fantasy?

Reginster, Jean-Yves; Bruyère, Olivier; Henrotin, Yves

2003 • In Journal of Rheumatology. Supplement, 67 (Suppl. 67), p. 14-20

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https://hdl.handle.net/2268/93245

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12926646

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Keywords :

Anti-Inflammatory Agents/pharmacology/therapeutic use; osteoarthritis; structure modification; Chondroitin Sulfates/metabolism/pharmacology/therapeutic use; trontium ranelate; Glucosamine/metabolism/pharmacology/therapeutic use; glucosamine sulfate; Humans; chondroitin sulfate; Nonprescription Drugs/standards/therapeutic use; diacerein; Osteoarthritis/drug therapy/pathology/physiopathology; treatment; Plant Oils/metabolism/pharmacology/therapeutic use

Abstract :

[en] Several entities have been carefully investigated for the symptomatic and structural management of osteoarthritis (OA). The most compelling evidence of a potential for inhibiting the structural progression of OA has been obtained with glucosamine sulfate, while some preliminary results also suggest that other compounds could be used in the same indication. At any rate, several medications have clearly demonstrated a symptomatic action, mainly in OA of the lower limbs, including pain relief and improvement of functional disability. An important issue is that all conclusive studies with such chemical entities resulted from the use of prescription medicines and not over-the-counter or nutriceutical supplements.

Disciplines :

Public health, health care sciences & services
Rheumatology

Author, co-author :

Reginster, Jean-Yves ; Université de Liège - ULiège > Département des sciences de la santé publique > Epidémiologie et santé publique

Bruyère, Olivier ; Université de Liège - ULiège > Département des sciences de la santé publique > Epidémiologie et santé publique

Henrotin, Yves ; Université de Liège - ULiège > Unité de recherche sur l'os et le cartillage (U.R.O.C.)

Language :

English

Title :

New perspectives in the management of osteoarthritis. Structure modification: Facts or fantasy?

Publication date :

August 2003

Journal title :

Journal of Rheumatology. Supplement

ISSN :

0380-0903

Publisher :

J Rheumatol Publ Co, Toronto, Canada

Volume :

67

Issue :

Suppl. 67

Pages :

14-20

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 17 June 2011

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10

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7

OpenAlex citations

9

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