[en] During pregnancy, the endocrine function of the gonads and the foeto-placental unit involves the synthesis of several hormones (progesterone, oestrogens, cortisol, prostaglandins, prolactin, chorionic gonadotropin, placental lactogen, also designed "chorionic somatomammotropin", etc.), and a series of growth factors and proteins. Some proteins and glycoproteins synthesized during gestation interfere with the establishment of pregnancy, corpus luteum maintenance, intermediate maternal metabolism, fetal growth, mammary growth and immunotolerance of the conceptus by the mother. This review includes a presentation of the main pregnancy-related hormones and proteins and their hypothetical role on the immunological status of the mother. [fr] Pendant la gestation, la fonction endocrinienne des gonades et de l’unité fœto-placentaire comprend la production de diverses hormones (progestérone, œstrogènes, cortisol, prostaglandines, prolactine, gonadotropine chorionique, hormone lactogène placentaire, aussi connue sous le nom de "somatomammotropine chorionique", etc.), de facteurs de croissance et de protéines diverses. Parmi ces dernières, se retrouvent les protéines et glycoprotéines impliquées dans de nombreux processus biologiques, dont : l’établissement de la gestation, le maintien du corps jaune, le métabolisme intermédiaire maternel, la croissance fœtale et mammaire et l’immuno-tolérance du conceptus. Les principales protéines et hormones associées à la gestation et leur relation éventuelle avec la fonction immune seront passées en revue sur base des connaissances actuelles disponibles dans la littérature scientifique
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Melo de Sousa, Noelita ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction
Figueiredo, J. R.
El Amiri, Bouchra
Banga-Mboko, Henri
Beckers, Jean-François ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction
Language :
French
Title :
Potential influence of pregnancy hormones and proteins synthesized during pregnancy on the maternal immunological status
Alternative titles :
[fr] Influence potentielle des hormones et protéines synthétisées au cours de la gestation sur l'état immunitaire de la mère
Publication date :
2002
Journal title :
Annales de Médecine Vétérinaire
ISSN :
0003-4118
eISSN :
1781-3875
Publisher :
ULg - Université de Liège, Liège, Belgium
Volume :
146
Issue :
2
Pages :
71-82
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
CAPES - Coordenação de Aperfeicoamento de Pessoal de Nível Superior
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