Regolazione della crescité follicolare e luteinica. Folliculogenesi e atresia. Summa.

Hypophyseal production of FSH and LH depends on a pulsating secretion of GnRH by the Hypothalamus. At the beginning of the cycle, this secretion sets free the FSH from the hypothesis responsible for follicular recruiment. The recruited follicles produce estradiol, inhibin and follistatin which reduce the FSH secretion (negative feed back) reducing their support to hormonodependant follicles which become atresic. The dominant follicle, subjected to internal self stimulation is not sensitive to the reduction in FSH levels and carries on synthesising more and more estradiol.