Reference : Existe-t-il une "memoire therapeutique" en prevention cardiovasculaire?
Scientific journals : Article
Human health sciences : Cardiovascular & respiratory systems
Human health sciences : Pharmacy, pharmacology & toxicology
Existe-t-il une "memoire therapeutique" en prevention cardiovasculaire?
[en] Does a "therapeutic memory" exist in cardiovascular prevention?
Scheen, André mailto [Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale >]
Revue Médicale Suisse
1864-6, 1868-9
Yes (verified by ORBi)
[en] Angiotensin-Converting Enzyme Inhibitors/therapeutic use ; Antilipemic Agents/therapeutic use ; Cardiovascular Diseases/prevention & control ; Diabetes Mellitus, Type 2/prevention & control ; Humans ; Hypoglycemic Agents/therapeutic use ; Life Style
[en] The prevention of type 2 diabetes and of cardiovascular diseases is a major public health objective. Obviously life-style changes play a major role in this strategy. The Finnish Prevention Study recently demonstrated that the remarkable diabetes prevention observed after a 4-year lifestyle intervention is maintained after a further 3-year period of follow-up without prolongation of the active intervention. Such a reminiscent effect may also be observed in the prevention of cardiovascular diseases with various pharmacological interventions: an ACE inhibitor (HOPE), a statin (4S), a fibrate (Helsinki Heart Study) or an intensive insulin therapy in type I diabetic patients (DCCT-EDIC). These intriguing results argue for a long-term memory of previous therapeutic interventions in cardiovascular prevention.
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