Cattle; Iodine; Selenium; Thyroid hormones; TSH; TRH
Abstract :
[en] Iodine (I) and selenium (Se) deficiencies are commonly reported in cattle, however, there are also studies regarding a very high iodine supply. The aim of the study was to determine the long-term effect of I and Se supplementation on non-pregnant cows, pregnant cows and their calves. The hypothalamus pituitary axis was investigated (TSH, T4, T3 assays) during a TRH challenge on non-pregnant cows. Twenty-four cows, half of them pregnant, were assigned into 2 diet-groups, one group with a low I (0.45 ppm) and Se (0.15 ppm) diet (LISe), the other with a high I (5.45 ppm) and Se (0.45 ppm) diet (HISe), for a period of 120 days. Nutritional (plasma iodide, urinary I, plasma Se, I content in colostrum and foetal fluids) and functional (thyrotropin, thyroid hormones, glutathione-peroxidase activity in erythrocytes) markers of
I and Se status were assayed in dams at regular intervals for 120 days and in their calves at birth. A TRH challenge was performed on 8 non-pregnant cows at day 110 of the trial. At the end of the study, I and Se nutritional markers were higher in dams in the HISe group, compared to the LISe group, except for plasma Se. At birth, I nutritional markers in calves in the HISe group were higher compared to the LISe group. Reactivity of the pituitary–thyroid-axis was not influenced by I and Se supplementation. I and Se supplementation is efficient in improving newborn status.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Guyot, Hugues ; Université de Liège - ULiège > Département clinique des animaux de production (DCP) > Médecine interne des équidés, des ruminants et des porcs
Alves de Oliveira, Laurent
Ramery, Eve ; Université de Liège - ULiège > Département de sciences fonctionnelles > Biochimie
Beckers, Jean-François ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction
Rollin, Frédéric ; Université de Liège - ULiège > Département clinique des animaux de production (DCP) > Médecine interne des équidés, des ruminants et des porcs
Language :
English
Title :
Effect of a combined iodine and selenium supplementation on I and Se status of cows and their calves
Alternative titles :
[fr] Effets d'une supplémentation combinée en I et Se sur le statut en I et Se de vaches et de leurs veaux
Zimmermann M.B. Iodine deficiency in pregnancy and the effects of maternal iodine supplementation on the offspring: a review. Am J Clin Nutr 2009, 89:668-672.
Vandevijvere S., Annemans L., Van Oven H., Tafforeau J., Moreno-Reyes R. Projected reduction in healthcare costs in Belgium after optimization of iodine intake: impact on costs related to thyroid nodular disease. Thyroid 2010, 20:1301-1306.
Commission Regulation (EC) N°1459/2005 of 9th September 2005 amending the conditions for authorisation of a number of feed additives belonging to the group of trace elements. Official Journal of the European Union 2005;L233/8.
Mee J.F., Rogers P.A.M. Prevalence of iodine, selenium, copper and cobalt deficiencies on Irish cattle farms. Ir Vet J 1996, 49:160-164.
Guyot H., Saegerman C., Lebreton P., Sandersen C., Rollin F. Epidemiology of trace elements deficiencies in Belgian beef and dairy cattle herds. J Trace Elem Med Biol 2009, 23:116-123.
Graham T.W. Trace elements deficiencies in cattle. Vet Clin North Am Food Anim Pract 1991, 7:153-215.
Awadeh F.T., Kincaid R.L., Johnson K.A. Effect of level and source of dietary selenium on concentrations of thyroid hormones and immunoglobulins in beef cows and calves. J Anim Sci 1998, 76:1204-1215.
Zagrodzki P., Nicol F., McCoy M.A., Smyth J.A., Kennedy D.G., Beckett G.J., et al. Iodine deficiency in cattle: compensatory changes in thyroidal selenoenzymes. Res Vet Sci 1998, 64:209-211.
Swanson E.W., Miller J.K., Mueller F.J., Patton C.S., Bacon J.A., Ramsey N. Iodine in milk and meat of dairy cows fed different amounts of potassium iodide or ethylenediamine dihydroiodide. J Dairy Sci 1990, 73:398-405.
Hemingway R.G., Fishwick G., Parkins J.J., Ritchie N.S. Plasma inorganic iodine and thyroxine concentrations for beef cows in late pregnancy and early lactation associated with different levels of dietary iodine supplementation. Vet J 2001, 162:158-160.
Guyot H., Sulon J., Beckers J.-F., Closset J., Lebreton P., Alves de Oliveira L., et al. Development and validation of a radioimmunoassay for thyrotropin in cattle. J Vet Diagn Invest 2007, 19:643-651.
Guyot H., Spring P., Andrieu S., Rollin F. Comparative responses to sodium selenite and organic selenium supplements in Belgian Blue cows and calves. Livest Sci 2007, 111:259-263.
Counotte G.H.M., Hartmans J. Relation between selenium content and glutathione-peroxidase activity in blood of cattle. Vet Quart 1989, 11:155-160.
Knowles S.O., Grace N.D., Wurms K., Lee J. Significance of amount and form of dietary selenium on blood, milk, and casein selenium concentrations in grazing cows. J Dairy Sci 1999, 82:429-437.
Aumont G., Tressol J.-C. Rapid method for the direct determination of inorganic iodine in plasma using ion-exchange chromatography and the Sandell and Kolthoff reaction. Analyst 1987, 112:875-878.
Ihaka R., Gentleman R. R: a language for data analysis and graphics. J Comput Graph Stat 1996, 5:299-314.
Chapter 6: minerals - trace minerals. Nutrient requirements of dairy cattle 2001, 132-148. Washington, DC, National Academy Press. National Research Council (Ed.).
Bitman J., Kahl S., Wood D.L., Lefcourt A.M. Circadian and ultradian rhythms of plasma thyroid hormone concentrations in lactating dairy cows. Am J Physiol 1994, 266:1797-1803.
Akasha M.A., Anderson R.R., Ellersieck M., Nixon D.A. Concentration of thyroid hormones and prolactin in dairy cattle serum and milk at three stages of lactation. J Dairy Sci 1987, 70:271-276.
Glinoer D. Pregnancy and Iodine. Thyroid 2001, 11:471-481.
Goret E.A., Vanjonack W.J., Johnson H.D. Plasma TSH and thyroxine in six breeds of cattle. J Anim Sci 1974, 38:1335.
Takahashi K., Takahashi E., Ducusin R.J.T., Tanabe S., Uzuka Y., Sarashina T. Changes in serum thyroid hormones levels in newborn calves as a diagnostic index of endemic goiter. J Vet Med Sci 2001, 63:175-178.
Potter B.J., Mano M.T., Belling G.B., McIntosh G.H., Hua C., Cragg B.G., et al. Retarded fetal brain development resulting from severe dietary iodine deficiency in sheep. Neuropathol Appl Neurobiol 1982, 8:303-313.
McCoy M.A., Smyth J.A., Ellis W.A., Arthur J.R., Kennedy D.G. Experimental reproduction of iodine deficiency in cattle. Vet Rec 1997, 141:544-547.
Wichtel J.J., Craigie A.L., Freeman D.A., Varela-Alvarez H., Williamson N.B. Effect of selenium and iodine supplementation on growth rate and on thyroid and somatotropic function in dairy calves at pasture. J Dairy Sci 1996, 79:1865-1872.
Abend S.L., Fang S.L., Alex S., Braverman L.E., Leonard J.L. Rapid alteration in circulating free thyroxine modulates pituitary type II 5' deiodinase and basal thyrotropin secretion in the rat. J Clin Invest 1991, 88:898-903.
Enjalbert F., Lebreton P., Salat O. Effects of copper, zinc and selenium status on performance and health in commercial dairy and beef herds: retrospective study. J Anim Physiol Anim Nutr 2006, 90:459-466.
Gerloff B.F. Effect of selenium supplementation on dairy cattle. J Anim Sci 1992, 70:3934-3940.
Pavlata L., Slosarkova S., Fleischer P., Pechova A. Effects of increased iodine supply on the selenium status of kids. Vet Med Czech 2005, 50:186-194.
Radetti G., Zavallone A., Gentili L., Beck-Peccoz P., Bona G. Foetal and neonatal thyroid disorders. Minerva Pediatr 2002, 54:383-400.
Nathanielsz P.W. Thyroid function in the fetus and newborn mammal. Br Med Bull 1975, 31:51-56.
Chopra I.J., Sack J., Fisher D.A. 3,3',5'-Triiodothyronine (reverse T3) and 3,3',5-triiodothyronine (T3) in fetal and adult sheep: studies of metabolic clearance rates, production rates, serum binding, and thyroidal content relative to thyroxine. Endocrinology 1975, 97:1080-1088.
Nikolic J.A., Kulcsar M., Katai L., Nedic O., Janosi S., Huszennicza G. Periparturient endocrine and metabolic changes in healthy cows and in cows affected by mastitis. J Vet Med A 2003, 50:22-29.
Convey E.M., Chapin L., Thomas J.W., Leung K., Swanson E.W. Serum thyrotropin, thyroxin, and tri-iodothyronine in dairy cows fed varying amounts of iodine. J Dairy Sci 1978, 61:771-775.
Elsasser T.H., Rumsey T.S., Norton S.A. Relationships between the thyroid and somatotropic axes in steers. I. Effects of propylthiouracil-induced hypothyroidism on growth hormone, thyroid stimulating hormone and insulin-like growth factor I. Domest Anim Endocrinol 1992, 9:261-271.
