Reference : Laminin promotes cerebellar granule cells migration in vitro and is synthesized by cu...
Scientific journals : Article
Life sciences : Biochemistry, biophysics & molecular biology
Human health sciences : Neurology
http://hdl.handle.net/2268/87657
Laminin promotes cerebellar granule cells migration in vitro and is synthesized by cultured astrocytes
English
SELAK, Ivan mailto [Centre Hospitalier Universitaire de Liège - CHU > > Neurologie Sart Tilman >]
Foidart, Jean-Michel mailto [Université de Liège - ULiège > Département des sciences cliniques > Gynécologie - Obstétrique >]
Moonen, Gustave mailto [Université de Liège - ULiège > Département des sciences cliniques > Neurologie >]
1985
Developmental Neuroscience
7
5-6
278-285
Yes (verified by ORBi)
International
0378-5866
1421-9859
[en] Newborn rat cerebellum microexplants have been used as a model to study neuronal migration. Laminin in a substrate-bound form modifies extensively the migratory behavior of the neurones, an effect which is blocked if antilaminin antibodies are present during the assay. 35S methionine incorporation followed by SDS-PAGE electrophoresis, fluorography and immunoprecipitation with antilaminin antibodies allowed to demonstrate that laminin is synthesized and secreted by cultured newborn rat cerebellum as well as by cultured newborn rat cerebral cortex astrocytes.
http://hdl.handle.net/2268/87657
also: http://hdl.handle.net/2268/94527

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