Reference : Canine eosinophilic bronchopneumopathy
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Life sciences : Veterinary medicine & animal health
Canine eosinophilic bronchopneumopathy
Clercx, Cécile mailto [Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Pathologie médicale des petits animaux >]
Peeters, Dominique mailto [Université de Liège - ULiège > > Clinique des petits animaux >]
Veterinary Clinics of North America. Small Animal Practice
W B Saunders Co-Elsevier Inc
[en] Eosinophilic bronchopneumopathy (EBP) is a disease characterized by eosinophilic infiltration of the lung and bronchial mucosa, as demonstrated by examination of bronchoalveolar lavage fluid cytologic preparations or histologic examination of the bronchial mucosa. Although the precise cause of EBP is unknown, a hypersensitivity to aeroallergens is suspected. The diagnosis relies on typical history and clinical signs, demonstration of bronchopulmonary eosinophilia by cytology or histopathologic examination, and exclusion of known causes of lower airway eosinophilia. Most dogs display an excellent response to oral corticosteroid therapy; however, side effects of this treatment can be limiting. New therapeutic approaches are being studied, including the use of aerosol therapy, cyclosporine, or drugs interfering with T helper 2 immune response.
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