Reference : EEMCO guidance for the efficacy assessment of antiperspirants and deodorants.
Scientific journals : Article
Human health sciences : Dermatology
EEMCO guidance for the efficacy assessment of antiperspirants and deodorants.
Pierard, Gérald mailto [Centre Hospitalier Universitaire de Liège - CHU > > Dermatopathologie >]
Elsner, P. [> > > >]
Marks, R. [> > > >]
Masson, P. [> > > >]
Paye, Marc [Université de Liège - ULiège > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine) >]
Skin Pharmacology and Applied Skin Physiology
S. Karger
Yes (verified by ORBi)
[en] Apocrine Glands/secretion ; Clinical Trials as Topic/legislation & jurisprudence/methods ; Deodorants/adverse effects/pharmacology ; Eccrine Glands/secretion ; Humans ; Practice Guidelines as Topic ; Sweat/secretion ; Sweating/drug effects
[en] Overproduction of sweat, sweaty skin and body odours are unpleasant for many social groups. Body cleansing products are designed to combat these undesirable features of skin. In addition, antiperspirant and deodorant products are more specifically used in the underarm site by a large part of the adult population. Antiperspirants are offered to control emotionally triggered sweating in the armpit. Deodorants are designed to combat malodour generated from bacteria-modified sweat. This review summarizes the physiology of eccrine, apocrine and apoeccrine sweat glands. The mechanisms of action of antiperspirants and deodorants are described as well as the factors influencing their efficacies. A series of tests using various measurement methods can be used to demonstrate the efficacy of antiperspirants. These include the gravimetric method, water evaporation quantification, electrodermal measurements, staining procedures, dye injections and cyanoacrylate skin surface strippings and casting replicas. Deodorant efficacy can be evaluated by sensory assessments performed by an expert panel. Indirect support is provided by visualization of apocrine gland excretion and collection of sweat and volatile compounds. Microbiological assessments and chromatographic analysis also provide indirect information.
Copyright 2003 S. Karger AG, Basel

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