Antigens of the basement membrane and the peritumoral stroma in human colonic adenocarcinomas: an immunofluorescence study.

Burtin, P.; Chavanel, G.; Foidart, Jean-Michel; Martin, E.

doi:10.1002/ijc.2910300104

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Antigens of the basement membrane and the peritumoral stroma in human colonic adenocarcinomas: an immunofluorescence study.

Burtin, P.; Chavanel, G.; Foidart, Jean-Michel et al.

1982 • In International Journal of Cancer, 30 (1), p. 13-20

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/84478

DOI
10.1002/ijc.2910300104

PubMed
6749699

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Abstract :

[en] Twenty colonic adenocarcinomas were studied by immunofluorescence with antisera against components of the basement membrane: type IV collagen, laminin and heparan sulfate-rich proteoglycan, as well as antisera against antigens of the connective tissue: type-III collagen, fibronectin and hyaluronectin. Marked alterations of the basement membranes were consistently observed on staining with each one of the first three antisera. In contrast, staining of the normal components of connective tissue was in most cases as intense as in normal colonic mucosa. Hyaluronectin, a marker of peritumoral stroma, was found to be present in 12 out 15 tumors studied.

Disciplines :

Biochemistry, biophysics & molecular biology

Author, co-author :

Burtin, P.

Chavanel, G.

Foidart, Jean-Michel ; Université de Liège - ULiège > Département des sciences cliniques > Gynécologie - Obstétrique - Labo de biologie des tumeurs et du développement

Martin, E.

Language :

English

Title :

Antigens of the basement membrane and the peritumoral stroma in human colonic adenocarcinomas: an immunofluorescence study.

Publication date :

1982

Journal title :

International Journal of Cancer

ISSN :

0020-7136

eISSN :

1097-0215

Publisher :

Wiley Liss, Inc., New York, United States - New York

Volume :

Issue :

Pages :

13-20

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 11 February 2011

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Bibliography

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