Hypercholesterolaemia in a family of rough collie dogs.

Animals; Cholesterol/blood; Cholesterol, HDL/blood; Cholesterol, LDL/blood; Cholesterol, VLDL/blood; Diagnosis, Differential; Dog Diseases/blood/diagnosis/genetics; Dogs; Female; Genetic Predisposition to Disease; Hypercholesterolemia/diagnosis/genetics/veterinary; Male; Pedigree

Abstract :

[en] A family of five privately owned rough collie dogs was referred for corneal lipidosis and also suffered from hypercholesterolaemia. The hypercholesterolaemia was characterised by an increase in the alpha-2 high density lipoprotein-1 band and was due to an increase in the cholesterol content of the very low density lipoprotein, low density lipoprotein and possibly the high density lipoprotein-1 fractions. A low-fat and energy-restricted diet did not reduce either total cholesterol or the corneal lipidosis. Corneal lipidosis regressed with short-chain fructo-oligosaccharide supplementation. However, the effects of short-chain fructo-oligosaccharides on total cholesterol were transient and variable.

Disciplines :

Veterinary medicine & animal health

Author, co-author :

Jeusette, Isabelle

Grauwels, Magda ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Département clinique des animaux de compagnie et des équidés

Cuvelier, Christine ; Université de Liège - ULiège > Département de sciences fonctionnelles > Pharmacologie, pharmacothérapie et toxicologie

Tonglet, Catherine

Istasse, Louis ; Université de Liège - ULiège > Département de productions animales > Nutrition des animaux domestiques

Diez, Marianne ; Université de Liège - ULiège > Département de productions animales > Nutrition des animaux domestiques

Language :

English

Title :

Hypercholesterolaemia in a family of rough collie dogs.

Publication date :

2004

Journal title :

Journal of Small Animal Practice

ISSN :

0022-4510

eISSN :

1748-5827

Publisher :

Blackwell Publishing, Oxford, United Kingdom

Volume :

Issue :

Pages :

319-24

Peer reviewed :

Peer Reviewed verified by ORBi

Funders :

ULiège - Université de Liège

Available on ORBi :

since 10 March 2009

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Bibliography

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