[en] Plasma prekallikrein and kininogens were assayed by specific enzymatic and immunological methods in cirrhotic patients with terminal liver failure and during oestrogenic impregnation. In cirrhotic patients plasma levels of these substances were significantly lowered and they correlated negatively with necrosis enzymes. A highly significant positive correlation was found between coagulation factor values and the levels of prekallikrein and kininogens. During oestrogenic impregnation the levels of the constituents of the kallikrein-kinin system were significantly increased when compared with reference values. These findings indicate that plasma concentrations of prekallikrein and kininogens are dependent upon liver synthesis capacity.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Adam, Akram ; Centre Hospitalier Universitaire de Liège - CHU > Salle Médecine A NDB
Reynaert, M.
Damas, Pierre ; Université de Liège - ULiège > Soins intensifs
Lamy, Maurice ; Centre Hospitalier Universitaire de Liège - CHU > Anesthésie et réanimation
Damas, Jacques ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques
Language :
French
Title :
Synthèse protéique hépatique du système kallikréine-kininogènes-kinines
Alternative titles :
[en] Hepatic protein synthesis of the kallikrein-kininogen-kinin system