Sujets de poids normal «métaboliquement obèses» et sujets obèses «métaboliquement sains»

[fr] Les relations entre poids corporel et anomalies métaboliques ne sont pas univoques. Ainsi, il existe des personnes non obèses métaboliquement anormales (MONW), rarement dépistées en raison d’un poids corporel faussement rassurant, et, à l’inverse, des sujets métaboliquement sains bien qu’ils soient obè ses (MHO). La topographie (intra-abdominale/hépatique vs sous-cutanée périphérique) et l’activité hormono-métabolique et pro-inflammatoire différente des dépôts graisseux semblent jouer un rôle déterminant pour expliquer ce paradoxe. Cet article de revue vise à décrire les grands principes de la prise en charge thérapeutique des personnes MONW, dans le but de réduire le risque accru de diabète de type 2 et de maladies cardiovasculaires, et de discuter les avantages et inconvénients d’une prise en charge classique de l’obésité chez les patients MHO.

Disciplines :

Endocrinology, metabolism & nutrition

Author, co-author :

Beck, Emmanuel ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques

ESSER, Nathalie

Paquot, Nicolas ; Université de Liège - ULiège > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine)

Scheen, André ; Université de Liège - ULiège > Département des sciences cliniques > Diabétologie, nutrition et maladie métaboliques - Médecine interne générale

Language :

French

Title :

Sujets de poids normal «métaboliquement obèses» et sujets obèses «métaboliquement sains»

Publication date :

2009

Journal title :

Revue Médicale de la Suisse Romande

ISSN :

0035-3655

Publisher :

Société Médicale de la Suisse Romande, Lausanne, Switzerland

Volume :

Pages :

1644-1649

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

http://revue.medhyg.ch

Available on ORBi :

since 17 December 2009

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