Progesterone; Early fetal period; Milk production; PAG; Dairy cows
Abstract :
[en] The aim of the present study was to determine whether certain animal- or management related factors could affect plasma progesterone concentrations on Day 42 of gestation in high producing dairy cows. Factors affecting early fetal loss were also analyzed. The study population was comprised of 199 pregnant cows classified as having high (> or =9 ng/ml) or low (<9 ng/ml) plasma progesterone concentrations. Through logistic regression procedures it was determined that, based on the odds ratio, cows with two or more corpora lutea were three times more likely to have high progesterone concentrations than cows with a single corpus luteum. Low producing cows during the warm season were 2.86 times more likely to have high progesterone concentrations than the remaining cows. Primiparous cows with high concentrations (>4 ng/ml) of pregnancy associated glycoprotein-1 (PAG-1) were 2.73 times more likely to have high progesterone concentrations than the remaining cows. Of the 199 pregnancies, 25 (12.6%) suffered early fetal loss: 22/136 (16.2%) during the warm season and 3/63 (4.8%) during the cool season, all in cows without additional corpora lutea. Based upon the odds ratio, cows without an additional corpus luteum were 3.67 times more likely to suffer fetal loss during the warm season than during the cool season. Our results indicate that milk production, the presence of two or more corpora lutea and plasma PAG-1 concentrations can affect plasma progesterone concentrations at the onset of the fetal period. The presence of an additional corpus luteum strongly diminished the risk of early fetal loss during the warm period.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Bech-Sabat, G.
Lopez-Gatius, F.
Yaniz, J. L.
Garcia-Ispierto, I.
Santolaria, P.
Serrano, B.
Sulon, Joseph ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction
Melo de Sousa, Noelita ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction
Beckers, Jean-François ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction
Language :
English
Title :
Factors affecting plasma progesterone in the early fetal period in high producing dairy cows.
scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.
Bibliography
Ball P.J.H. Later embryo and early fetal mortality in the cow. Anim Breed Abs 65 (1997) 167-175
Vanroose G., de Kruif A., and Van Soom A. Embryonic mortality and embryo-pathogen interactions. Anim Reprod Sci 60/61 (2000) 131-143
Committee on Bovine Reproductive Nomenclature, 1972. Recommendations for standardizing bovine reproductive terms. Cornell Vet 62 (1972) 216-237
Peters A.R. Embryo mortality in the cow. Anim Breed Abs 64 (1996) 587-598
Forar A.L., Gay J.M., and Hancock D.D. The frequency of endemic fetal loss in dairy cattle: a review. Theriogenology 43 (1995) 989-1000
Hanzen C.H., Drion P.V., Loutrie O., Depierreux C., and Christians E. Embyonic mortality. Part 1. Clinical aspects and etiological factors on the bovine species. Ann Med Vet 145 (1999) 91-118
Thurmond M.C., Picanso J.P., and Jameson C.M. Considerations for use of descriptive epidemiology to investigate fetal loss in dairy cows. J Am Vet Med Assoc 197 (1990) 1305-1312
Labèrnia J., López-Gatius F., Santolaria P., López-Béjar M., and Rutllant J. Influence of management factors on pregnancy attrition in dairy cattle. Theriogenology 45 (1996) 1247-1253
López-Gatius F., Santolaria P., Yaniz J., Rutllant J., and López-Béjar M. Factors affecting pregnancy loss from gestation day 38 to 90 in lactating dairy cows from a single herd. Theriogenology 57 (2002) 1251-1261
Silke V., Diskin M.G., Kenny D.A., Boland M.P., Dillon P., Mee J.F., et al. Extent, pattern and factors associated with late embryonic loss in dairy cows. Anim Reprod Sci 71 (2002) 1-12
Santos J.E.P., Thatcher W.W., Chebel R.C., Cerri R.L.A., and Galvão K.N. The effect of embryonic death rates in cattle on the efficacy of estrus synchronization programs. Anim Reprod Sci 82/83 (2004) 513-535
Grimard B., Freret S., Chevallier A., Pinto A., Ponsart C., and Humblot P. Genetic and environmental factors influencing first service conception rate and late embryonic/foetal mortalitiy in low fertility dairy herds. Anim Reprod Sci 91 (2006) 31-44
Sangsritavong S., Combs D.K., Sartori R., Armentano L.E., and Wiltbank M.C. High feed intake increases liver blood flow and metabolism of progesterone and estradiol-17β in dairy cattle. J Dairy Sci 85 (2002) 2831-2842
Spencer T.E., Johnson G.A., Burghart R.C., and Bazer F.W. Progesterone and placental hormone actions on the uterus: insights from domestic animals. Biol Reprod 71 (2004) 2-10
López-Gatius F., Santolaria P., Yániz J.L., and Hunter R.H.F. Progesterone supplementation during the early fetal period reduces pregnancy loss in high-yielding dairy cattle. Theriogenology 62 (2004) 1529-1535
López-Gatius F., Santolaria P., Yániz J.L., Garbayo J.M., and Hunter R.H.F. Timing of early foetal loss for single and twin pregnancies in dairy cattle. Reprod Domest Anim 39 (2004) 429-433
García-Ispierto I., López-Gatius F., Santolaria P., Yániz J.L., Nogareda C., López-Béjar M., et al. Relationship between heat stress during the peri-implantation period and early fetal loss in dairy cattle. Theriogenology 65 (2006) 799-807
Starbuck M.J., Dailey R.A., and Inskeep E.K. Factors affecting retention of early pregnancy in dairy cattle. Anim Reprod Sci 84 (2004) 27-39
National Research Council. Nutrient requirements of dairy cattle. 7th rev. ed. (2001), National Academy Science, Washington, DC
López-Gatius F., Garbayo J.M., Santolaria P., Yániz J., Ayad A., de Sousa N.M., et al. Milk production correlates negatively with plasma levels of pregnancy-associated glycoprotein (PAG) during the early fetal period in high producing dairy cows with live fetuses. Domest Anim Endocrinol 32 (2007) 29-42
Perényi Z., Szenci O., Sulon J., Drion P.V., and Beckers J.F. Comparison of the ability of three radioimmunoassay to detect pregnancy-associated glycoproteins in bovine plasma. Reprod Domest Anim 37 (2002) 100-104
Perényi Z., Szenci O., Drion P.V., Banga Mboko H., Sousa N.M., El Amiri B., et al. Aspartic proteinase members secreted by the ruminant placenta: specificity of three radioimmunoassay system for the measurement of pregnancy-associated glycoproteins. Reprod Domest Anim 37 (2002) 324-329
Vaitukaitis J., Robbins J.B., Nieschlag E., and Ross G.T. A method for producing specific antisera with small doses of immunogen. J Clin Endocrinol Metab 33 (1971) 988-991
Labèrnia J., López-Gatius F., Santolaria P., López-Béjar M., and Rutllant J. Influence of calving season on the interactions among reproductive disorders of dairy cows. Anim Sci 67 (1998) 387-393
López-Gatius F. Is fertility declining in dairy cattle? A retrospective study in northeastern Spain. Theriogenology 60 (2003) 89-99
Pegorer M.F., Vasconcelos J.L.M., Trinca L.A., Hansen P.J., and Barros C.M. Influence of sire and breed (Gyr versus Holstein) on establishment of pregnancy and embryonic loss in lactating Holstein cows during summer heat stress. Theriogenology 67 (2007) 692-697
Hosmer D.W., and Lemeshow S. Applied logistic regression (1989), Wiley, New York
Ayad A., Sousa N.M., Sulon J., Hornick J.L., Watts J., López-Gatius F., et al. Influence of progesterone concentrations on secretory functions of trophoblast and pituitary during the first trimester of pregnancy in dairy cattle. Theriogenology 67 (2007) 1503-1511
López-Gatius F., Hunter R.H.F., Garbayo J.M., Santolaria P., Yániz J., Serrano B., et al. Plasma concentrations of pregnancy-associated glycoprotein-1 (PAG-1) in high producing dairy cows suffering early fetal loss during the warm season. Theriogenology 67 (2007) 1324-1330
Harrison R.O., Ford S.P., Young J.W., Conley A.J., and Freeman A.E. Increased milk production versus reproductive and energy status of high producing dairy cows. J Dairy Sci 73 (1990) 2749-2758
Wiltbank M., Lopez H., Sartori R., Sangsritavong S., and Gümen A. Changes in reproductive physiology of lactating dairy cows due to elevated steroid metabolism. Theriogenology 65 (2006) 17-29
West J.W. Effects of heat-stress on production in dairy cattle. J Dairy Sci 86 (2003) 2131-2144
De Rensis F., and Scaramuzzi R.J. Heat stress and seasonal effects on reproduction in dairy cow - a review. Theriogenology 60 (2003) 1139-1151
Sawyer HR. Structural and functional properties of the corpus luteum of pregnancy. In: Scaramuzzi RJ, Nancarrow CD, Doberska C, editors. Reproduction in Domestic Ruminants III. Cambridge: J Reprod Fertil Ltd 1995:97-110.
Niswender G.D., Juengel J.L., Silva P.J., Rollyson M.K., and McIntush E.W. Mechanisms controlling the function and life span of the corpus luteum. Physiol Rev 80 (2000) 1-29
Mann G.E., Robinson R.S., and Hunter M.G. Corpus luteum size and function following single and double ovulations in non-lactating dairy cows. Theriogenology 67 (2007) 1256-1261
Schams D., and Berisha B. Regulation of corpus luteum function in cattle - an overview. Reprod Domest Anim 39 (2004) 241-251
Zoli A.P., Beckers J.F., Woutters-Ballman P., Closset J., Falmagne P., and Ectors F. Radioimmunoassay of a bovine pregnancy-associated glycoprotein in serum: its application for pregnancy diagnosis. Biol Reprod 46 (1992) 83-92
Mialon M.M., Camous S., Renand G., Martal J., and Ménissier F. Peripheral concentrations of a 60-kDa pregnancy serum protein during gestation and after calving and in relationship to embryonic mortality in cattle. Reprod Nutr Dev 33 (1993) 269-282
Green J.A., Parks T.E., Avalle M.P., Telugu B.P., McLain A.L., Peterson A.J., et al. The establishment of an ELISA for the detection of pregnancy-associated glycoproteins (PAGs) in the serum of pregnant cows and heifers. Theriogenology 63 (2005) 1481-1503
Skinner J., Gray D., Gebbie F., Beckers J.F., and Sulon J. Field evaluation of pregnancy diagnosis using bovine pregnancy-associated glycoprotein (bPAG). Cattle Pract 4 (1996) 281-284
Szenci O., Beckers J.F., Humblot P., Sulon J., Sasser G., Taverne M.A., et al. Comparison of ultrasonography, bovine pregnancy-specific protein B, and bovine pregnancy-associated glycoprotein 1 tests for pregnancy detection in dairy cows. Theriogenology 50 (1998) 77-88
Szenci O., Taverne M.A.M., Beckers J.F., Sulon J., Varga J., Börzsönyi L., et al. Evaluation of false ultrasonographic diagnoses in cows by measuring plasma levels of bovine pregnancy-associated glycoprotein 1. Vet Rec 142 (1998) 304-306
López-Gatius F., Santolaria P., Martino A., Delétang F., and De Rensis F. The effects of GnRH treatment at the time of AI and 12 days later on reproductive performance of high producing dairy cows during the warm season in northeastern Spain. Theriogenology 65 (2006) 820-830
Similar publications
Sorry the service is unavailable at the moment. Please try again later.
This website uses cookies to improve user experience. Read more
Save & Close
Accept all
Decline all
Show detailsHide details
Cookie declaration
About cookies
Strictly necessary
Performance
Strictly necessary cookies allow core website functionality such as user login and account management. The website cannot be used properly without strictly necessary cookies.
This cookie is used by Cookie-Script.com service to remember visitor cookie consent preferences. It is necessary for Cookie-Script.com cookie banner to work properly.
Performance cookies are used to see how visitors use the website, eg. analytics cookies. Those cookies cannot be used to directly identify a certain visitor.
Used to store the attribution information, the referrer initially used to visit the website
Cookies are small text files that are placed on your computer by websites that you visit. Websites use cookies to help users navigate efficiently and perform certain functions. Cookies that are required for the website to operate properly are allowed to be set without your permission. All other cookies need to be approved before they can be set in the browser.
You can change your consent to cookie usage at any time on our Privacy Policy page.
