Reference : Specific Passive Immunity Reduces the Excretion of Glycoprotein E-Negative Bovine Her...
Scientific journals : Article
Life sciences : Microbiology
Life sciences : Veterinary medicine & animal health
Specific Passive Immunity Reduces the Excretion of Glycoprotein E-Negative Bovine Herpesvirus Type 1 Vaccine Strain in Calves
Lemaire, Mylène [> > > >]
Hanon, E. [> > > >]
Schynts, Frédéric [> > > >]
Meyer, Gilles [> > > >]
Thiry, Etienne mailto [Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Virologie, épidémiologie et pathologie des maladies virales >]
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[en] We investigated the excretion of either a glycoprotein E (gE)-negative bovine herpesvirus type 1 (BHV1) vaccine strain or a conventional modified-live vaccine strain in both naive and passively immunised calves. The replication of gE-negative strain was considerably reduced in the maternally immunised calves, in comparison with the non-immune calves. On the other hand, the excretion of the gE-positive conventional vaccine strain was not reduced and even seemed to be prolonged in the presence of maternal antibodies. These results suggest that BHV1 gE may play a role in virus survival in the presence of antibodies.

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