Altar, C.A., Cai, N., Bliven, T., Juhasz, M., Conner, J.M., Acheson, A.L., Lindsay, R.M., Wiegand, S.J., Anterograde transport of brain-derived neurotrophic factor and its role in the brain (1997) Nature, 389, pp. 856-860
Baquet, Z.C., Gorski, J.A., Jones, K.R., Early striatal dendrite deficits followed by neuron loss with advanced age in the absence of anterograde cortical brain-derived neurotrophic factor (2004) J Neurosci, 24, pp. 4250-4258
Bingham, J.B., King, S.J., Schroer, T.A., Purification of dynactin and dynein from brain tissue (1998) Methods Enzymol, 298, pp. 171-184
Butler, R., Bates, G.P., Histone deacetylase inhibitors as therapeutics for polyglutamine disorders (2006) Nat Rev Neurosci, 7, pp. 784-796
Butowt, R., von Bartheld, C.S., Conventional kinesin-I motors participate in the anterograde axonal transport of neurotrophins in the visual system (2007) J Neurosci Res, , in press
Ciechanover, A., Brundin, P., The ubiquitin proteasome system in neurodegenerative diseases: Sometimes the chicken, sometimes the egg (2003) Neuron, 40, pp. 427-446
Drummond, D.C., Noble, C.O., Kirpotin, D.B., Guo, Z., Scott, G.K., Benz, C.C., Clinical development of histone deacetylase inhibitors as anticancer agents (2005) Annu Rev Pharmacol Toxicol, 45, pp. 495-528
Evans, L., Mitchison, T., Kirschner, M., Influence of the centrosome on the structure o0f nucleated microtubules (1985) J Cell Biol, 100, pp. 1185-1191
Gaertig, J., Cruz, M.A., Bowen, J., Gu, L., Pennock, D.G., Gorovsky, M.A., Acetylation of lysine 40 in alpha-tubulin is not essential in Tetrahymena thermophila (1995) J Cell Biol, 129, pp. 1301-1310
Gauthier, L.R., Charrin, B.C., Borrell-Pages, M., Dompierre, J.P., Rangone, H., Cordelieres, F.P., De Mey, J., Saudou, F., Huntingtin controls neurotrophic support and survival of neurons by enhancing BDNF vesicular transport along microtubules (2004) Cell, 118, pp. 127-138
Goldstein, L.S., Laymon, R.A., McIntosh, J.R., A microtubule-associated protein in Drosophila melanogaster: Identification, characterization, and isolation of coding sequences (1986) J Cell Biol, 102, pp. 2076-2087
Gunawardena, S., Her, L.S., Brusch, R.G., Laymon, R.A., Niesman, I.R., Gordesky-Gold, B., Sintasath, L., Goldstein, L.S., Disruption of axonal transport by loss of huntingtin or expression of pathogenic polyQ proteins in Drosophila (2003) Neuron, 40, pp. 25-40
Haggarty, S.J., Koeller, K.M., Wong, J.C., Grozinger, C.M., Schreiber, S.L., Domain-selective small-molecule inhibitor of histone deacetylase 6 (HDAC6)-mediated tubulin deacetylation (2003) Proc Natl Acad Sci USA, 100, pp. 4389-4394
Hartmann, M., Heumann, R., Lessmann, V., Synaptic secretion of BDNF after high-frequency stimulation of glutamatergic synapses (2001) EMBO J, 20, pp. 5887-5897
Haubensak, W., Narz, F., Heumann, R., Lessmann, V., BDNF-GFP containing secretory granules are localized in the vicinity of synaptic junctions of cultured cortical neurons (1998) J Cell Sci, 111, pp. 1483-1493
Hempen, B., Brion, J.P., Reduction of acetylated alpha-tubulin immunoreactivity in neurofibrillary tangle-bearing neurons in Alzheimer's disease (1996) J Neuropathol Exp Neurol, 55, pp. 964-972
Hu E, Dul E, Sung CM, Chen Z, Kirkpatrick R, Zhang GF, Johanson K, Liu R, Lago A, Hofmann G, Macarron R, de los Frailes M, Perez P, Krawiec J, Winkler J, Jaye M (2003) Identification of novel isoform-selective inhibitors within class I histone deacetylases. J Pharmacol Exp Ther 307:720-728
Hubbert, C., Guardiola, A., Shao, R., Kawaguchi, Y., Ito, A., Nixon, A., Yoshida, M., Yao, T.P., HDAC6 is a microtubule-associated deacetylase (2002) Nature, 417, pp. 455-458
Humbert, S., Bryson, E.A., Cordelieres, F.P., Connors, N.C., Datta, S.R., Finkbeiner, S., Greenberg, M.E., Saudou, F., The IGF-1/Akt pathway is neuroprotective in Huntington's disease and involves Huntingtin phosphorylation by Akt (2002) Dev Cell, 2, pp. 831-837
Ingold, A.L., Cohn, S.A., Scholey, J.M., Inhibition of kinesin-driven microtubule motility by monoclonal antibodies to kinesin heavy chains (1988) J Cell Biol, 107, pp. 2657-2667
Iwata, A., Riley, B.E., Johnston, J.A., Kopito, R.R., HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin (2005) J Biol Chem, 280, pp. 40282-40292
Kamal, A., Almenar-Queralt, A., LeBlanc, J.F., Roberts, E.A., Goldstein, L.S., Kinesin-mediated axonal transport of a membrane compartment containing beta-secretase and presenilin-1 requires APP (2001) Nature, 414, pp. 643-648
Kawaguchi, Y., Kovacs, J.J., McLaurin, A., Vance, J.M., Ito, A., Yao, T.P., The deacetylase HDAC6 regulates aggresome formation and cell viability in response to misfolded protein stress (2003) Cell, 115, pp. 727-738
Kohara, K., Kitamura, A., Morishima, M., Tsumoto, T., Activity-dependent transfer of brain-derived neurotrophic factor to postsynaptic neurons (2001) Science, 291, pp. 2419-2423
Kozminski, K.G., Diener, D.R., Rosenbaum, J.L., High level expression of nonacetylatable alpha-tubulin in Chlamydomonas reinhardtii (1993) Cell Motil Cytoskeleton, 25, pp. 158-170
Krebs, A., Goldie, K.N., Hoenger, A., Complex formation with kinesin motor domains affects the structure of microtubules (2004) J Mol Biol, 335, pp. 139-153
Lee, W.C., Yoshihara, M., Littleton, J.T., Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease (2004) Proc Natl Acad Sci USA, 101, pp. 3224-3229
Ligon, L.A., Shelly, S.S., Tokito, M.K., Holzbaur, E.L., Microtubule binding proteins CLIP-170, EB1, and p150Glued form distinct plus-end complexes (2006) FEBS Lett, 580, pp. 1327-1332
Mallik, R., Petrov, D., Lex, S.A., King, S.J., Gross, S.P., Building complexity: An in vitro study of cytoplasmic dynein with in vivo implications (2005) Curr Biol, 15, pp. 2075-2085
Manders, E.M., Stap, J., Brakenhoff, G.J., van Driel, R., Aten, J.A., Dynamics of three-dimensional replication patterns during the S-phase, analysed by double labelling of DNA and confocal microscopy (1992) J Cell Sci, 103, pp. 857-862
Matsuyama, A., Shimazu, T., Sumida, Y., Saito, A., Yoshimatsu, Y., Seigneurin-Berny, D., Osada, H., Yoshida, M., In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation (2002) EMBO J, 21, pp. 6820-6831
McGuire, J.R., Rong, J., Li, S.H., Li, X.J., Interaction of Huntingtin-associated protein-1 with kinesin light chain: Implications in intracellular trafficking in neurons (2006) J Biol Chem, 281, pp. 3552-3559
Mizuno, N., Toba, S., Edamatsu, M., Watai-Nishii, J., Hirokawa, N., Toyoshima, Y.Y., Kikkawa, M., Dynein and kinesin share an overlapping microtubule-binding site (2004) EMBO J, 23, pp. 2459-2467
Nogales, E., Wolf, S.G., Downing, K.H., Structure of the alpha beta tubulin dimer by electron crystallography (1998) Nature, 391, pp. 199-203
North, B.J., Marshall, B.L., Borra, M.T., Denu, J.M., Verdin, E., The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase (2003) Mol Cell, 11, pp. 437-444
Pigino, G., Morfini, G., Pelsman, A., Mattson, M.P., Brady, S.T., Busciglio, J., Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport (2003) J Neurosci, 23, pp. 4499-4508
Piperno, G., Fuller, M.T., Monoclonal antibodies specific for an acetylated form of alpha-tubulin recognize the antigen in cilia and flagella from a variety of organisms (1985) J Cell Biol, 101, pp. 2085-2094
Qin, Z.H., Wang, Y., Kegel, K.B., Kazantsev, A., Apostol, B.L., Thompson, L.M., Yoder, J., DiFiglia, M., Autophagy regulates the processing of amino terminal huntingtin fragments (2003) Hum Mol Genet, 12, pp. 3231-3244
Ravikumar, B., Duden, R., Rubinsztein, D.C., Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy (2002) Hum Mol Genet, 11, pp. 1107-1117
Ravikumar, B., Acevedo-Arozena, A., Imarisio, S., Berger, Z., Vacher, C., O'Kane, C.J., Brown, S.D., Rubinsztein, D.C., Dynein mutations impair autophagic clearance of aggregate-prone proteins (2005) Nat Genet, 37, pp. 771-776
Reed, N.A., Cai, D., Blasius, T.L., Jih, G.T., Meyhofer, E., Gaertig, J., Verhey, K.J., Microtubule acetylation promotes kinesin-1 binding and transport (2006) Curr Biol, 16, pp. 2166-2172
Saragoni, L., Hernandez, P., Maccioni, R.B., Differential association of tau with subsets of microtubules containing posttranslationally-modified tubulin variants in neuroblastoma cells (2000) Neurochem Res, 25, pp. 59-70
Saudou, F., Finkbeiner, S., Devys, D., Greenberg, M.E., Huntingtin acts in the nucleus to induce apoptosis but death does not correlate with the formation of intranuclear inclusions (1998) Cell, 95, pp. 55-66
Seigneurin-Berny, D., Verdel, A., Curtet, S., Lemercier, C., Garin, J., Rousseaux, S., Khochbin, S., Identification of components of the murine histone deacetylase 6 complex: Link between acetylation and ubiquitination signaling pathways (2001) Mol Cell Biol, 21, pp. 8035-8044
Shaner, N.C., Campbell, R.E., Steinbach, P.A., Giepmans, B.N., Palmer, A.E., Tsien, R.Y., Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp. red fluorescent protein (2004) Nat Biotechnol, 22, pp. 1567-1572
Skiniotis, G., Cochran, J.C., Muller, J., Mandelkow, E., Gilbert, S.P., Hoenger, A., Modulation of kinesin binding by the C-termini of tubulin (2004) EMBO J, 23, pp. 989-999
Stepanova, T., Slemmer, J., Hoogenraad, C.C., Lansbergen, G., Dortland, B., De Zeeuw, C.I., Grosveld, F., Galjart, N., Visualization of microtubule growth in cultured neurons via the use of EB3-GFP (end-binding protein 3-green fluorescent protein) (2003) J Neurosci, 23, pp. 2655-2664
Stokin, G.B., Lillo, C., Falzone, T.L., Brusch, R.G., Rockenstein, E., Mount, S.L., Raman, R., Goldstein, L.S., Axonopathy and transport deficits early in the pathogenesis of Alzheimer's disease (2005) Science, 307, pp. 1282-1288
Szebenyi, G., Morfini, G.A., Babcock, A., Gould, M., Selkoe, K., Stenoien, D.L., Young, M., Brady, S.T., Neuropathogenic forms of huntingtin and androgen receptor inhibit fast axonal transport (2003) Neuron, 40, pp. 41-52
Taddei, A., Roche, D., Bickmore, W.A., Almouzni, G., The effects of histone deacetylase inhibitors on heterochromatin: Implications for anticancer therapy? (2005) EMBO Rep, 6, pp. 520-524
Toomre, D., Keller, P., White, J., Olivo, J.C., Simons, K., Dual-color visualization of trans-Golgi network to plasma membrane traffic along microtubules in living cells (1999) J Cell Sci, 112, pp. 21-33
Trettel, F., Rigamonti, D., Hilditch-Maguire, P., Wheeler, V.C., Sharp, A.H., Persichetti, F., Cattaneo, E., MacDonald, M.E., Dominant phenotypes produced by the HD mutation in STHdh(Q111) striatal cells (2000) Hum Mol Genet, 9, pp. 2799-2809
Trushina, E., Dyer, R.B., Badger II, J.D., Ure, D., Eide, L., Tran, D.D., Vrieze, B.T., Bender, A., Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro (2004) Mol Cell Biol, 24, pp. 8195-8209
Vaughan, K.T., Tynan, S.H., Faulkner, N.E., Echeverri, C.J., Vallee, R.B., Colocalization of cytoplasmic dynein with dynactin and CLIP-170 at microtubule distal ends (1999) J Cell Sci, 112, pp. 1437-1447
Wada, Y., Hamasaki, T., Satir, P., Evidence for a novel affinity mechanism of motor-assisted transport along microtubules (2000) Mol Biol Cell, 11, pp. 161-169
Webb, J.L., Ravikumar, B., Rubinsztein, D.C., Microtubule disruption inhibits autophagosome-lysosome fusion: Implications for studying the roles of aggresomes in polyglutamine diseases (2004) Int J Biochem Cell Biol, 36, pp. 2541-2550
Westermann, S., Weber, K., Post-translational modifications regulate microtubule function (2003) Nat Rev Mol Cell Biol, 4, pp. 938-947
Xia, Z., Dudek, H., Miranti, C.K., Greenberg, M.E., Calcium influx via the NMDA receptor induces immediate early gene transcription by a MAP kinase/ERK-dependent mechanism (1996) J Neurosci, 16, pp. 5425-5436
Yano, H., Chao, M.V., Mechanisms of neurotrophin receptor vesicular transport (2004) J Neurobiol, 58, pp. 244-257
Zhang, Y., Li, N., Caron, C., Matthias, G., Hess, D., Khochbin, S., Matthias, P., HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo (2003) EMBO J, 22, pp. 1168-1179
