[en] Since mid-december 2003, an epizootic of highly pathogenic avian influenza (type A, sub-type H5N1) occurs in eastern and south-eastern Asia. This epizootic is historically unprecedented in its virulence, geographical spread, and economic consequences for the agricultural sector. Implications for human health were registered in Vietnam and in Thailand. This paper summarizes the current knowledge about the risk evaluation of the transmission of avian influenza virus to humans. The current asian epizootic has highlighted the key role of global health information systems and also the need for exhaustive notification of human and animal cases. It reinforces the concept of veterinary public health.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Saegerman, Claude ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Epidémiologie et analyse des risques appl. aux sc. vétér.
Meulemans, G.
Van Reeth, K.
Marlier, Didier ; Université de Liège - ULiège > Médecine des oiseaux, des lagomorphes et des rongeurs
Yane, F.
Vindevogel, Henri ; Université de Liège - ULiège > Services généraux (Faculté de médecine vétérinaire) > Relations académiques et scientifiques (Méd. vétérinaire)
Brochier, B.
van den Berg, T.
Thiry, Etienne ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Virologie, épidémiologie et pathologie des maladies virales
Language :
French
Title :
Risk evaluation of the transmission of the avian influenza virus to humans
AGENCE FÉDÉRALE POUR LA SÉCURITÉ DE LA CHAÎNE ALIMENTAIRE. SERVICE D'ENCADREMENT, DE PRÉVENTION ET DE GESTION DE CRISE. BELGIQUE. Mesures de précaution contre l'influenza aviaire. Document CPC-044 du 21 avril 2003. Agence fédérale pour la Sécurité de la chaîne alimentaire: Bruxelles, 2003a, 2 p.
AGENCE FÉDÉRALE POUR LA SÉCURITÉ DE LA CHAÎNE ALIMENTAIRE. Meeting of the Standing Committee of the Food Chain and Animal Health, 28 May 2003. Belgium, Avian Influenza: follow-up report, Agence fédérale pour la Sécurité de la chaîne alimentaire: Bruxelles, 2003b, 12 p.
AGENCE FRANÇAISE DE SÉCURITÉ SANITAIRE DES ALIMENTS. Rapport du groupe de travail sur le risque de transmission à l'homme des virus influenza aviaires adopté par le Comité d'experts spécialisé en santé animale le 10 juillet 2002. Agence française de Sécurité sanitaire des aliments: Paris, 2002, 95 p.
AIELLO S.E. The Merck Veterinary manual. 8th Ed. Merck & Co: Rahwey, 1998, 2305 p.
ALEXANDER D.J. The epidemiology and control of avian influenza and Newcastle disease. J. Comp. Pathol., 1995, 112, 105-126.
ALEXANDER D.J. A review of avian influenza in different bird species. Vet. Microbiol., 2000, 74, 3-13.
ALEXANDER D.J., PARSONS G., MANVELL R.J. Experimental assessment of the pathogenicity of eight avian influenza A viruses of H5 subtype for chickens, turkeys, ducks and quail. Avian Pathol., 1986, 15, 647-662.
BANKS J., SPEIDEL E., ALEXANDER D.J. Characterisation of an avian influenza A virus isolated from a human - is an intermediate host necessary for the emergence of pandemic influenza viruses? Arch. Virol., 1998, 143, 781-787.
BEARD C.W., SCHNITZLEIN W.M., TRIPATHY D.N. Protection of chickens against highly pathogenic avian influenza virus (H5N2) by recombinant fowlpox viruses. Avian Dis., 1991, 35, 356-359.
BEARD C.W., SCHNITZLEIN W.M., TRIPATHY D.N. Effect of administration on the efficacity of a recombinant fowlpox virus against H5N2 avian influenza. Avian Dis., 1992, 36, 1052-1055.
BOYLE D.B., SELLECK P., HEINE H.G. Vaccinating chickens against avian influenza with fowlpox recombinants expressing the H7 haemagglutinin. Aust. Vet. J., 2000, 78, 44-48.
BROWN I.H., CHAKRAVERTY P., HARRIS P.A., ALEXANDER D.J. Diseases outbreaks in pigs in Great Britain due to an influenza Avirus of H1N2 subtype. Vet. Rec., 1995, 136, 328-329.
BROWN I.H., HARRIS P.A., MCCAULEY J.W., ALEXANDER D.J. Multiple genetic reassortment of avian and human influenza A viruses in european pigs, resulting in the emergence of an H1N2 virus of novel genotype. J. Gen. Virol., 1998, 79, 2947-2955.
BUXTON BRIDGES C., KATZ J.M., SETO W.H., CHAN P.K., TSANG D., HO W., MAK K.H., LIM W., TAM K.S., CLARKE M., WILLIAMS S.G., MOUNTS A.W., BRESEE J.S., CONN L.A., ROWE T., HU-PRIMMER J., ABERNATHY R.A., LU X., COX N.J., FUKUDA K. Risk of influenza A (H5N1) infection among health care workers exposed to patients with influenza A (H5N1), Hong Kong. J. Infect. Dis., 2000, 181, 344-8.
CAPUA I., MARANGON S. Avian influenza in Italy (1999-2000): a review. Avian Pathol., 2000, 29, 289-294.
CAPUA I., MARANGON S., DALLA POZZA M., SANTUCCI U. Vaccination for avian influenza in Italy. Vet. Rec., 2000, 147, 751.
CAPUA I., ALEXANDER D. J. Avian influenza and human health. Acta Tropica, 2002, 83, 1-6.
CAPUA I., MUTINELLI F., DALLA POZZA M., DONATELLI I., PUZELLI S., MARIA CANCELLOTI F. The 1999-2000 avian influenza (H7N1) epidemic in Italy: veterinary and human health implications. Acta Tropica, 2002, 83, 7-11.
CAPUA I., MARANGON S. La vaccination en tant qu'outil utilisable contre l'influenza aviaire. In: Organisation mondiale de la Santé animale. 71ème Session Générale du Comité International, Paris, 18-23 mai 2003, document 71 SG/12/CS3 E. Organisation mondiale de la Santé animale: Paris, 2003, 10 p.
CASTRUCCI M.R., DONATELLI I., SIDOLI L., BARIGAZZI G., KAWAOKA Y., WEBSTER R.G. Genetic reassortment between avian and human influenza A viruses in Italian pigs. Virology, 1993, 193, 503-506.
CENTERS FOR DISEASE CONTROL AND PREVENTION OF ATLANTA. Outbreaks of avian influenza A (H5N1) in Asia and interim recommendations for evaluation and reporting of suspected cases: United States, 2004. Morb. Mortal. Wkly Rep., 2004, 53, 97-100
CHAN P.K. Outbreak of avian influenza A (H5N1) virus infection in Hong Kong in 1997. Clin. Infect. Dis., 2002, 34, 58-64.
CHOTPITAYASUNONDH T., LOCHINDARAT S., SRISAN P. Cases of influenza A (H5N1): Thailand. Morb. Mortal. Wkly Rep., 2004, 53, 100-103.
CLAAS E.C., KAWAOKA Y., DE JONG J.C., MASUREL N., WEBSTER R.G. Infection of children with avian-human reassortant influenza virus from pigs in Europe. Virology, 1994, 204, 453-457.
CLAAS E.C., OSTERHAUS A.D., VAN BEEK R., DE JONG J.C., RIMMELZWAAN G.F., SENNE D.A., KRAUSS S., SHORTRIDGE K.F., WEBSTER R.G. Human influenza A H5N1 virus related to a highly pathogenic avian influenza virus. Lancet, 1998, 351, 460-461.
COMMISSION EUROPÉENNE. DIRECTORAT GÉNÉ-RAL DE LA SANTÉ ET DE LA PROTECTION DU CONSOMMATEUR. COMITÉ SCIENTIFIQUE DE LA SANTÉ ET DU BIEN-ÊTRE ANIMAL. The definition of avian influenza. The use of vaccination against avian influenza. Document Sanco/B3/AH/R17/2000, draft report for possible adoption on 27 June 2000. Commission européenne: Bruxelles, 2000a, 36 p.
COMMISSION EUROPÉENNE. Décision 2000/666/CE du 16 octobre 2000 arrêtant les conditions de police sanitaire et la certification vétérinaire requises pour les importations d'oiseaux, à l'exclusion des volailles, ainsi que les conditions de quarantaine. J. Off. Commun. Eur., 2000b, L278, 26-34.
CONSEIL DE L'EUROPE. Directive 92/40/CEE du 19 mai 1992, établissant des mesures communautaires de lutte contre l'influenza aviaire. J. Off. Commun. Eur., 1992, L167, 1-16.
CONSEIL SUPÉRIEUR D'HYGIÈNE. La protection de la santé humaine dans le cadre de la problématique de la peste aviaire: avis provisoire du Conseil supérieur d'hygiène 7851 approuvé le 2 mai 2003. [en ligne] (5 mai 2003) Adresse URL: http://www.health.fgov.be/CSH_HGR/Francais/Avis/Av is_Peste_Aviaire.htm Consulté le 15/02/2004.
EASTERDAY B.C., HINSHAW V.S., HALVORSON D.A. Influenza. In: Calnek B.W., Barnes H.J., Beard C.W., Mc Dougald L.R., Saif Y.M. (Ed.), Diseases of Poultry, 10th edition, Iowa state University Press: Ames, 1997, 583-605.
EASTERDAY B.C., VAN REETH K. Swine influenza. In : Straw B.E., Allair S.D., Mengeling W.L., Taylor D.J. (Ed.), Diseases of swine, 8th edition, Iowa state University Press: Ames, 1999, 89-92.
EUROPEAN COMMISSION. SCIENTIFIC COMMITTEE ON ANIMAL HEALTH AND ANIMAL WELFARE. The definition of avian influenza. The use of vaccination against avian influenza. Document Sanco/B3/AH/R17/2000. European Commission: Brussels, 2000, 36 p.
EUROPEAN COMMISSION. SCIENTIFIC COMMITTEE ON ANIMAL HEALTH AND ANIMAL WELFARE. Diagnostic techniques and vaccines for foot-and-mouth disease, classical swine fever, avian influenza and some other important OIE list A diseases: report of the Scientific Committee on Animal Health and Animal Welfare adopted 24-25th April 2003. [en ligne] (01/05/2003) Adresse URL: http://europa.eu.int/comm/food/fs/sc/scah/out93_en.pdf Consulté le 15/02/2004a.
EUROPEAN COMMISSION. DIRECTORATE-GENERAL HEALTH AND CONSUMER PROTECTION. Outbreaks of H5 avian influenza in Asia. [en ligne] (04/02/2004) Adresse URL : http://europa.eu.int/comm/health/ph_threats/com/Influenza/images/pathogenic.jpg Consulté le 15/02/2004b.
EUROPEAN COMMISSION. DIRECTORATE-GENERAL HEALTH AND CONSUMER PROTECTION. Recent outbreaks of H5 avian influenza in Asia and confirmed human cases. [en ligne] (04/02/2004) Adresse URL: http://europa.eu.int/comm/health/ph_threats/ com/Influenza/images/influenza.jpg Consulté le 15/02/2004c.
EUROPEAN COMMISSION. HEALTH AND CONSUMER PROTECTION DIRECTORATE-GENERAL. Low pathogenic avian influenza (LPAI) in Italy. Report on the implementation of the emergency vaccination program. Document SANCO/10018/2004. European Commission: Brussel, 2004d, 34 p.
FITCH W.M., BUSH R.M., BENDER C.A., COX N.J. Long term trends in the evolution of H(3) HA1 human influenza type A. Proc. Natl. Acad. Sci. USA, 1997, 94, 7712-7718.
FOUCHIER R.A., SCHNEEBERGER P.M., ROZENDAAL F.W., BROEKMAN J.M., KEMINK S.A., MUNSTER V., KUIKEN T., RIMMELZWAAN G.F., SCHUTTEN M., VAN DOORNUM G.J., KOCH G., BOSMAN A., KOOPMANS M., OSTERHAUS A.D. Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome. Proc. Natl. Acad. Sci. USA, 2004, 10, 1073.
GAMBARYAN A., WEBSTER R., MATROSOVICH M. Differences between influenza virus receptors on target cells of duck and chicken. Arch. Virol., 2002, 147, 1197-1208.
GAMBARYAN A.S., TUZIKOV A.B., BOVIN N.V., YAMNIKOVA S.S., LVOV D.K., WEBSTER R.G., MATROSOVICH M.N. Differences between influenza virus receptors on target cells of duck and chicken and receptor specificity of the 1997 H5N1 chicken and human influenza viruses from Hong Kong. Avian Dis., 2003, 47, 1154-1160
GARCIA A., JOHNSON H., SRIVASTAVA D.K., JAYAWARDENE D.A., WEHR D.R., WEBSTER R.G. Efficacy of inactivated H5N2 inlfuenza vaccines against lethal A/Chicken/Queretar/19/95 infection. Avian Dis., 1998, 42, 248-256.
GUBAREVA L.V., MCCULLERS J.A., BETHELL R.C., WEBSTER R.G. Characterization of influenza A/HongKong/156/97 (H5N1) virus in a mouse model and protective effect of zanamivir on H5N1 infection in mice. J. Infect. Dis., 1998, 178, 1592-1596.
HIRST G.K., PONS M.W. Mechanism of influenza recombination. II. Virus aggregation and its effect on plaque formation by so-called noninfective virus. Virology, 1973, 56, 620-631.
ITO T., OKAZAKI K., KAWAOKA Y., TAKADA A., WEBSTER R.G., KIDA H. Perpetuation of influenza A viruses in Alaskan waterfowl reservoirs. Arch. Virol., 1995, 140, 1163-117 2.
ITO T., KAWAOKA Y., VINES A., ISHIKAWA H., ASAI T., KIDA H. Continued circulation of ressortant H1N2 influenza viruses in pigs in Japan. Arch. Virol., 1998, 143, 1773-1782.
KAWAOKA Y., NAEVE C.W., WEBSTER R.G. Is virulence of H5N2 influenza viruses in chickens associated with loss of carbohydrate from the hemagglutinin? Virology, 1984 , 139, 303-316.
KAWAOKA Y., NESTOROWICZ A., ALEXANDER D.J., WEBSTER R.G. Molecular analyses of the hemagglutinin genes of H5 influenza viruses: origin of a virulent turkey strain. Virology, 1987, 158, 218-227.
KIDA H., ITO T., YASUDA J., SHIMIZU Y., ITAKURA C., SHORTRIDGE K.F., KAWAOKA Y., WEBSTER R.G. Potential for transmission of avian influenza viruses to pigs. J. Gen. Virol., 1994, 75, 2183-2188.
KOOPMANS M., FOUCHIER R., WILBRINK B., MEIJER A., NATROP G., OSTERHOUS A.D.M.E., VAN STEENBERGEN J.E., DU RY VAN BEEST HOLLE M., CONYN VAN SPAENDONCK M.A.E., BOSMAN A. Update on human infections with highly pathogenic avian influenza virus A/H7N7 during an outbreak in poultry in the Netherlands. [en ligne] 1/05/2003 Adresse URL:http://www.eurosurveillance.org/ew/2003/030501.asp Consulté le 1/07/2003.
KURTZ J., MANVELL R.J., BANKS, J. Avian influenza virus isolated from a woman with conjunctivitis. Lancet, 1996, 348, 901-902.
LENEVA I.A., ROBERTS N., GOVORKOVA E.A., GOLOUBEVA O.G., WEBSTER R.G. The neuraminidase inhibitor GS4104 (oseltamivir phosphate) is efficacious against A/Hong Kong/156/97 (H5N1) and A/HongKong/1074/99 (H9N2) influenza viruses. Antiviral Res., 2000, 48, 101-115.
LIN Y.P., SHAW M., GREGORY V., CAMERON K., LIM W., KLIMOV A., SUBBARAO K., GUAN Y., KRAUSS S., SHORTRIDGE K., WEBSTER R., COX N., HAYA. Avian-to-human transmission of H9N2 subtype influenza A viruses: relationship between H9N2 and H5N1 human isolates. Proc. Natl. Acad. Sci. USA, 2000, 97, 9654-9658.
LOEFFEN W., DE BOER-LUIJTZE E., KOCH G. Infections with avian influenza virus (H7N7) in Dutch pigs. In: Proceedings of the 6th International Congress of the European Society for Veterinary Virology, 24-27 August 2003, St. Malo, France. Jestin A. (AFSSA): Ploufragan, 2003, 50.
LUSCHOW D., WERNER O., METTENLEITER T.C., FUCHS W. Protection of chickens from lethal avian influenza A virus infection by live-virus vaccination with infectious laryngotracheitis virus recombinants expressing the hemagglutinin (H5) gene. Vaccine, 2001, 19, 4249-4259.
MANVELL R.J., JORGENSEN P.H., NIELSEN O.L., ALEXANDER D.J. Experimental assessment of the pathogenicity of two avian influenza A H5 viruses in ostrich chicks (Struthio camelus) and chickens. Avian Pathol., 1998, 27, 400-404.
MARAGON S., BORTOLOTTI L., CAPUA I., BETTIO M., DALLA POZZA M. Low-pathogenicity avian influenza (LPAI) in Italy (2002-01): epidemiology and control. Avian Dis., 2003, 47, 1006-1009.
MEULEMANS G., VAN DEN BERG T. Peste aviaire. [en ligne] (21/04/2003) Adresse URL:http://www.var.fgov.be/pesteavaire_fr.php Consulté le 01/07/2003.
MINISTÈRE DES AFFAIRES SOCIALES ET DE LA SANTÉ PUBLIQUE. BELGIQUE. Mesures de protection de la santé publique en cas de risque de transmission de la peste aviaire en provenance du Sud-est Asiatique. Circulaire CS/SC/730 du 6 février 2004. Ministère des Affaires sociales et de la Santé publique: Bruxelles, 6 p.
ORGANISATION MONDIALE DE LA SANTÉ. Le point sur les épidémies. Grippe A(H5N1), Hong Kong, Région administrative spéciale de la Chine. Relev. Epidémiol. Hebd., 2003a, 78, 49-50.
ORGANISATION MONDIALE DE LA SANTÉ. Le point sur les épidémies. Grippe A(H5N1), Hong Kong, Région administrative spéciale de la Chine: mise à jour. Relev. Epidémiol. Hebd., 2003b, 78, 57-58.
ORGANISATION MONDIALE DE LA SANTÉ. Le point sur les épidémies. Elaboration d'un vaccin efficace contre le virus H5N1 de la grippe aviaire chez l'homme. Relev. Epidémiol. Hebd., 2004a, 79, 25-40.
ORGANISATION MONDIALE DE LA SANTÉ. Le point sur les épidémies. Grippe aviaire A (H5N1). Relev. Epidémiol. Hebd., 2004b, 79, 43-64.
ORGANISATION MONDIALE DE LA SANTÉ. Le point sur les épidémies. Grippe aviaire A (H5N1). Relev. Epidémiol. Hebd., 2004c, 79, 65-76.
ORGANISATION MONDIALE DE LA SANTÉ ANIMALE. Informations sanitaires. [en ligne] (15/02/2004) Adresse URL:http://www.oie.int/fr/info/ hebdo/f_info.htm Consulté le 15/02/2004.
PEIRIS M., YUEN K.Y., LEUNG C.W., CHAN K.H., IP P.L., LAI R.W., ORR W.K., SHORTRIDGE K.F. Human infection with influenza H9N2. Lancet, 354, 916-917.
PENSAERT M., OTTIS K., VANDEPUTTE J., KAPLAN M.M., BACHMAN P.A. Evidence for the natural transmission of influenza A virus from wild ducks to swine and its potential for man. Bull. World Health Organ., 1981, 59, 75-78.
ROBINSON J.H., EASTERDAY B.C. Avian influenza virus infection of the immunosuppressed turkey. Am. J. Vet. Res., 1979, 40, 1219-1222.
ROGERS G.N., PAULSON J.C. Receptor determinants of human and animal influenza virus isolates: differences in receptor specificity of the H3 hemagglutinin based on species of origin. Virology, 1983, 127, 361-373.
SCHOLTISSEK C., BURGER H., BACHMANN P.A., HANNOUN C. Genetic relatedness of hemagglutinins of the H1 subtype of influenza A viruses isolated from swine and birds. Virology, 1983, 129, 521-523.
SHORTRIDGE K.F., ZHOU N.N., GUAN Y., GAO P., ITO T., KAWAOKA Y., KODIHALLI S., KRAUSS S., MARKWELL D., MURTI K.G., NORWOOD M., SENNE D., SIMS L., TAKADA A., WEBSTER R.G. Characterization of avian H5N1 influenza viruses from poultry in Hong Kong. Virology, 1998, 252, 331-342.
STALLKNECHT D.E., SHANE S.M. Host range of avian influenza virus in free-living birds. Vet. Res. Com., 1988, 12, 125-141.
STALLKNECHT D.E., SHANE S.M., KEARNEY M.T., ZWANK P.J. Persistence of avian influenza viruses in water. Avian Dis., 1990, 34, 406-411.
STONE D.H. Efficacy of avian influenza oil-emulsion vaccines in chickens of various ages. Avian Dis., 1987, 31, 483-490.
SUBBARAO K., KLIMOV A., KATZ J., REGNERY H., LIM W., HALL H., PERDUE M., SWAYNE D., BENDER C., HUANG J., HEMPHILL M., ROWE T., SHAW M., XU X., FUKUDA K., COX N. Characterisation of an avian influenza A (H5N1) virus isolated from a child with a fatal respiratory illness. Science, 1998, 279, 393-396.
SWAYNE D.E., BECK J.R., MICKLE T.R. Efficacity of recombinant fowl poxvirus vaccine in protecting chickens against a highly pathogenic Mexican-origin H5N2 avian influenza virus. Avian Dis., 1997, 41, 910-922.
SWAYNE D.E., GARCIA M., BECK J.R., KINNEY N., SUAREZ D.L. Protection against diverse highly pathogenic H5 avian influenza viruses in chickens immunized with a recombinant fowlpox vaccine containing an H5 avian influenza hemagglutinin gene insert. Vaccine, 2000, 18, 1088-1095.
SWAYNE D.E., BECK J.R., PERDUE M.L., BEARD C.W. Efficacy of vaccines in chickens against highly pathogenic Hong Kong H5N1 avian influenza. Avian Dis., 2001, 45, 355-365.
SWAYNE D.E. Vaccines for list A poultry diseases: emphasis on avian influenza. Dev. Biol. (Basel), 2003, 114, 201-212.
TOMA B., BÉNET J.-J., DUFOUR B., ELOIT M., MOUTOU F., SANAA M. Glossaire d'épidémiologie animale. Le Point Vété rinaire: Paris, 1991, 365 p.
VAN KOLFSCHOOTEN F. Dutch veterinarian becomes first victim of avian influenza. Lancet, 2003, 9367, 1444.
WEBSTER R.G., BEAN W.J., GORMAN O.T., CHAMBERS T.M., KAWAOKA Y. Evolution and ecology of influenza A viruses. Microbiol. Rev., 1992, 56, 152-179.
WEBSTER R.G., TAYLOR J., PEARSON J.E., RIVERA E., PAOLETTI E. Immunity to Mexican H5N2 avian influenza viruses induced by a fowl pox- H5 recombinant. Avian Dis., 1996, 40, 461-465.
WINQUIST A.G., FUKUDA K., BRIDGES C.B., COX N.J. Neuraminidase inhibitors for treatment of influenza A and B infections. Morb. Mortal. Wkly Rep., 1999, 47, 1-9
YASUDA J., SHORTRIDGE K.F., SHIMIZU Y., KIDA H. Molecular evidence for a role of domestic ducks in the introduction of avian H3 influenza viruses to pigs in southern China, where the A/Hong Kong/68 (H3N2) strain emerged. J. Gen. Virol., 1991, 72, 2007-2010.
YUEN K.Y., CHAN P.K., PEIRIS M., TSANG D.N., QUE T.L., SHORTRIDGE K.F., CHEUNG P.T., TO W.K., HO E.T., SUNG R., CHENG A.F. Clinical features and rapid viral diagnosis of human disease associated with avian influenza A H5N1 virus. Lancet, 1998, 351, 467-471.
ZHOU N.N., SENNE D.A., LANDGRAF J.S., SWENSON S.L., ERIKSON G., ROSSOW K., LIU L., YOON K., KRAUSS S., WEBSTER R.G. Genetic reassortment of avian, swine, and human influenza A viruses in American pigs. J. Virol., 1999, 73, 8851-8856.
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