Paper published in a journal (Scientific congresses and symposiums)
A live attenuated glycoprotein E negative bovine herpesvirus 1 vaccine induces a partial cross-protection against caprine herpesvirus 1 infection in goats
Thiry, Julien; Tempesta, M.; Camero, M.et al.
2006 • In Veterinary Microbiology, 113 (3-4), p. 303-308
[en] Taking into account the close antigenic relationship between bovine herpesvirus 1 (BoHV-1) and caprine herpesvirus 1 (CpHV-1), a live attenuated glycoprotein E (gE) negative BoHV-1 vaccine was assessed in goats with the aim to protect against CpHV-1 infection. Vaccine safety was evaluated by intranasal inoculation of two groups of goats with either a gE-negative BoHV-1 vaccine or a virulent BoHV-1. The length of viral excretion and the peak viral titre were reduced with the gE-negative vaccine. To assess the efficacy, two goats were inoculated intranasally twice 2 weeks apart with a gE-negative BoHV-1 vaccine. Four weeks later, immunised and control goats were challenged with CpHV-1. A 2 log(10) reduction in the peak viral titre was observed and the challenge virus excretion lasted 2 days more in immunised than in control goats. These data indicate the safety and the partial efficacy of a live attenuated gE-negative BoHV-1 vaccine intranasally administrated in goats. (c) 2005 Elsevier B.V. All rights reserved.
Disciplines :
Veterinary medicine & animal health Microbiology
Author, co-author :
Thiry, Julien ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Virologie, épidémiologie et pathologie des maladies virales
Tempesta, M.
Camero, M.
Tarsitano, E.
Bellacicco, A. L.
Thiry, Etienne ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Virologie, épidémiologie et pathologie des maladies virales
Buonavoglia, C.
Language :
English
Title :
A live attenuated glycoprotein E negative bovine herpesvirus 1 vaccine induces a partial cross-protection against caprine herpesvirus 1 infection in goats
Publication date :
31 March 2006
Event name :
Proceedings of the 2nd ESVV Veterinary Herpesvirus Symposium
C. Buonavoglia, M. Tempesta, A. Cavalli, V. Voigt, D. Buonavoglia, A. Conserva, and M. Corrente Reactivation of caprine herpesvirus 1 in latently infected goats Comp. Immunol. Microbiol. Infect. Dis. 19 1996 275 281
M. Engels, M. Palatini, A.E. Metzler, U. Probst, U. Kihm, and M. Ackermann Interactions of bovine and caprine herpesviruses with the natural and the foreign hosts Vet. Microbiol. 33 1992 69 78
M. Lemaire, F. Schynts, G. Meyer, and E. Thiry Antibody response to glycoprotein E after bovine herpesvirus type 1 infection in passively immunised, glycoprotein E negative calves Vet. Rec. 144 1999 172 176
M. Lemaire, F. Schynts, G. Meyer, J.P. Georgin, E. Baranowski, A. Gabriel, C. Ros, S. Belak, and E. Thiry Latency and reactivation of a glycoprotein E negative bovine herpesvirus type 1 vaccine: influence of virus load and effect of specific maternal antibodies Vaccine 19 2001 4795 4804
S.H. Madin, D.G. McKercher, and C.J. York Isolation of the infectious bovine rhinotracheitis virus Science 124 1956 721 722
M.H. Mars, M.C. De Jong, and J.T. van Oirschot A gE-negative bovine herpesvirus 1 vaccine strain is not re-excreted nor transmitted in an experimental cattle population after corticosteroid treatments Vaccine 18 2000 1975 1981
F. Mettler, M. Engels, P. Wild, and A. Bivetti Herpesvirus-infektion bei Zieklein in der Schweiz Schweiz. Arch. Tierheilkd. 121 1979 655 662
A. Six, M. Banks, M. Engels, C.R. Bascunana, and M. Ackermann Latency and reactivation of bovine herpesvirus 1 (BHV-1) in goats and of caprine herpesvirus 1 (CapHV-1) in calves Arch. Virol. 146 2001 1325 1335
M. Tempesta, A. Pratelli, M. Corrente, and C. Buonavoglia A preliminary study on the pathogenicity of a strain of caprine herpesvirus-1 Comp. Immunol. Microbiol. Infect. Dis. 22 1999 137 143
M. Tempesta, M. Camero, G. Greco, A. Pratelli, V. Martella, and C. Buonavoglia A classical inactivated vaccine induces protection against caprine herpesvirus 1 infection in goats Vaccine 19 2001 3860 3864
E. Thiry, M. Ackermann, M. Banks, K. Belak, S. Belak, I. Campbell, C. Ek-Kommonen, M. Engels, G. Meyer, H. Reid, C. Ros, and A. Six Risk evaluation of cross-infection of cattle with ruminant alphaherpesviruses related to bovine herpesvirus type 1 R. Körber Third Internationales Symposium zur BHV-1-/BVD-Bekämpfung Druck & Werbung, Stendal 2001 99 104
F.A. Uzal, L. Woods, M. Stillian, R. Nordhausen, D.H. Read, H. Van Kampen, J. Odani, S. Hietala, E.J. Hurley, M.L. Vickers, and S.M. Gard Abortion and ulcerative posthitis associated with caprine herpesvirus-1 infection in goats in California J. Vet. Diagn. Invest. 16 2004 478 484
J.T. van Oirschot, M. Kaashoek, and F.A.M. Rijsewijk Advances in the development and evaluation of bovine herpesvirus 1 vaccines Vet. Microbiol. 53 1996 43 54
S. Vilcek Detection of the bovine herpesvirus-1 (BHV-1) genome by PCR J. Virol. Meth. 41 1993 245 247
N.M. Williams, M.L. Vickers, R.R. Tramontin, M.B. Petrites-Murphy, and G.P. Allen Multiple abortions associated with caprine herpesvirus infection in a goat herd J. Am. Vet. Med. Assoc. 211 1997 89 91
