[en] Plasma enhanced chemical vapor deposition has been tested for the formation of hydrophobic perfluorinated coating on the surface of hydrophilic poly(2-hydroxyethyl methacrylate-co-methyl methacrylate) [poly(HEMA-co-MMA)] substrates, used for the fabrication of intraocular lenses (IOLs). The properties of the dry and hydrated surface modified by two plasma techniques, Radio-frequency (RF) and Microwave (MW), were investigated in parallel by contact angle measurements in the dry and hydrated state, X-ray photoelectron spectroscopy, and atomic force microscopy. The coating stability and hydrophobicity were challenged by swelling and sterilizing the samples in water. Investigation of the optical performances of the modified samples was performed by ultraviolet spectroscopy and diopter measurements. Since materials with biomedical application are considered, the performances of their surface in contact with lens epithelial cells were tested at in vitro conditions, and repulsion was not found to be enhanced upon modification. Generally, the results showed poor stability of the coating and bring in question its covalent grafting to the surface.
Research Center/Unit :
Center for Education and Research on Macromolecules (CERM)
Disciplines :
Chemistry Materials science & engineering
Author, co-author :
Bozukova, Dimitriya; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Pagnoulle, Christophe; Physiol SA, Belgium
De Pauw-Gillet, Marie-Claire ; Université de Liège - ULiège > Biomedical Sciences and Preclinical Department > Laboratory of Histology and Cytology
Klee, Doris; RWTH Aachen, Germany > Lehrstuhl für Textilchemie und Makromolekulare Chemie
Dupont-Gillain, Christine; Université Catholique de Louvain (UCL) > Unité de Chimie des Interfaces
Duwez, Anne-Sophie ; Université de Liège - ULiège > Department of Chemistry > Nanochemistry and Molecular Systems
Gilbert, Yann; Université de Liège - ULiège > Department of Chemistry > Nanochemistry and Molecular Systems
Jérôme, Robert ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Jérôme, Christine ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Language :
English
Title :
Plasma surface fluorination of hydrogel materials-coating stability and in vitro biocompatibility testing
The Walloon Region of Belgium in the frame of the “First Europe (SURFOLIO) program BELSPO - SPP Politique scientifique - Service Public Fédéral de Programmation Politique scientifique
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