Article (Scientific journals)
EEMCO guidance for the assessment of hair shedding and alopecia.
Pierard, Gérald; Pierard, Claudine; Marks, R. et al.
2004In Skin Pharmacology and Physiology, 17 (2), p. 98-110
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Keywords :
Alopecia/physiopathology/prevention & control; Hair/growth & development/physiopathology; Humans; Methods
Abstract :
[en] Knowledge of the hair follicle anatomy and the dynamics of hair cycling is substantial. Recognizing the anagen, catagen and telogen phases as well as teloptosis and the hair eclipse phenomenon clearly characterizes the typical hair chronobiology. Physiological modulators include hormones, neuromediators, miscellaneous biomolecules, seasons, micro-inflammation and ageing. For individuals who present with the complaint of increased hair shedding or alopecia, a host of evaluation techniques are available in addition to history, physical examination and laboratory assessment. Various clinical hair techniques can help in assessing the efficacy of drugs and cosmetics on hair growth. The methods are quite similar to those used to establish a definite diagnosis in dermatological practice. Great strides have been made during the recent decades in the methodology of hair growth trials in dermatology and cosmetology. Clinical evaluations benefit from a few additional specific techniques that enhance the perception of hair (re-) growth, shedding and alopecia. These assessments include the determination of hair patterning and density that may be helped by the 'black-and-white felt' examination. Daily hair counts, the 'hair pull test' and the 'hair feathering test' are also available. Instrumental methods provide reliable quantitative information that is useful if there are adequate controls. Some photographic methods, the trichogram, hair weighing and variants of the hair growth window technique including the phototrichogram, videotrichogram and tractio-phototrichogram provide insight into the complexities of hair cycling and shedding. Skin biopsy is indicated for diagnostic purposes, especially when the hair loss is accompanied by scarring.
Disciplines :
Dermatology
Author, co-author :
Pierard, Gérald ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Pierard, Claudine ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Marks, R.;  Cutest Systems Limited, Heath, Cardiff, Great Britain
Elsner, P.;  Department of Dermatology and Allergology, Friedrich Schiller University, Jena, Germany
Language :
English
Title :
EEMCO guidance for the assessment of hair shedding and alopecia.
Publication date :
2004
Journal title :
Skin Pharmacology and Physiology
ISSN :
1660-5527
eISSN :
1660-5535
Publisher :
S. Karger, Basel, Switzerland
Volume :
17
Issue :
2
Pages :
98-110
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 24 February 2009

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