Reference : Épidémiologie de la maladie rénale chronique en République démocratique du Congo: une...
Scientific journals : Article
Human health sciences : Urology & nephrology
http://hdl.handle.net/2268/68554
Épidémiologie de la maladie rénale chronique en République démocratique du Congo: une revue synthétique des études de Kinshasa, la capitale
French
[en] Epidemiology of chronie kidney disease in the Democratie Republic of Congo: Review of cross-sectional studies from Kinshasa, the capital
Sumaili, E. K. [Université de Kinshasa > Service de néphrologie, cliniques universitaires de Kinshasa > > >]
Krzesinski, Jean-Marie mailto [Université de Liège - ULiège > > Néphrologie >]
Cohen, E. P. [Zablocki VA Medical Center > Nephrology Section > > >]
Nseka, N. M. [Université de Kinshasa > Service de néphrologie, cliniques universitaires de Kinshasa > > >]
2010
Néphrologie & Thérapeutique
Elsevier
6
232–239
Yes (verified by ORBi)
International
1769-7255
1872-9177
Paris
France
[en] Arterial hypertension ; Chronic kidney disease ; Diabetes mellitus ; Epidemiology ; Equation (MDRD) ; Prevalence ; Proteinuria
[en] Chronic kidney disease (CKD) is a worldwide public health problem. Little is known about its burden in Africa. This paper reviews the knowledge of CKD in Kinshasa, summarizing four studies undertaken in the general population and traditional health system of Kinshasa. CKD was defined by either kidney damage (proteinuria 300 mg/day) or reduced kidney function (eGFR < 60 ml/min/1.73 m2). In the general population, the prevalence of CKD all stage is 12.4 %. Our work shows also the high prevalence of proteinuria among subjects who do not have diabetes or hypertension, the lack of early detection and management of CKD risk factors in the traditional health care system leading to late referral or premature deaths, and the limits of renal replacement treatment. CKD affects young people in the DRC, in contrast to the United States, where CKD is more prevalent in older people. Major determinants of CKD in our studies were hypertension, diabetes, overweight, age, lower socioeconomic status, and Human immunodeficiency virus (HIV) infection. Glomerular nephropathy (mainly focal segmental glomerulosclerosis) remains the leading cause of end stage renal disease. An annual screening of the population for proteinuria and CKD risk factors is feasible and will, it is hoped, provide the basis for building a nationwide prevention strategy.
Researchers ; Professionals
http://hdl.handle.net/2268/68554
also: http://hdl.handle.net/2268/69285
10.1016/j.nephro.2010.03.008

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