Unpublished conference/Abstract (Scientific congresses and symposiums)
Towards a Belgian Consensus for prevention of perinatal group B streptococcal disease
MELIN, Pierrette; Verschraegen, G.; Mahieu, Ludo et al.
2002XV Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD)


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Keywords :
Group B streptococci; perinatal infections; Prevention; consensus; Belgium
Abstract :
[en] Background & objectives: In Belgium, as in many other countries, group B Streptococcus (GBS) is still the leading cause of sepsis and meningitis in neonates. In 2001, though no Belgian guidelines for their prevention were available, in some hospitals, obstetrical programmes included a GBS prevention policy. With an aim to reach a Belgian consensus for the prevention of perinatal group B streptococcal disease, a national consensum meeting was organized in 2001. We report here our experience and findings of this meeting. Methods: In November 2001, obstetricians, neonatologists, microbiologists and infectious diseases specialists were invited to participate in a GBS symposium. International and Belgian speakers presented epidemiological aspects, argued comparative cost-effectiveness of different approaches for prevention and debated technical and practical problems. Management of neonates with risk factors for GBS disease and progress in GBS vaccines were also included in the programme. Further results about Belgian obstetricians’ practice and compliance to a policy for prevention of neonatal GBS diseases, as answered in two mail surveys, were commented and discussed. In an interactive session at the end, each participant was asked to vote on the key points related to the different steps of the ideal prevention strategy to recommend. Results: For the main questions, 94 per cent of participants choose a screening-based approach and 94 per cent shifted from the current use of ampicillin to penicillin as first choice for antimicrobial prophylaxis. Further, 79 per cent voted for an approach with integrated neonatal prophylaxis for selected neonates at high risk for GBS disease and 47 per cent voted for a strategy based on an intrapartum rapid screening-based approach. Interpretation & conclusion: The state of the question by different speakers, the data from Belgian epidemiology, and the debate about cost-effectiveness of different approaches led to a massive vote in favour of the universal screening-based approach. Based on these results, a working group has been appointed by the Ministry of Health to draft and edit Belgian recommendations for the prevention of perinatal GBS disease.
Disciplines :
Laboratory medicine & medical technology
Reproductive medicine (gynecology, andrology, obstetrics)
Immunology & infectious disease
Author, co-author :
MELIN, Pierrette  ;  Centre Hospitalier Universitaire de Liège - CHU > Microbiologie médicale
Verschraegen, G.;  Hôpital universitaire de Gand - RUG > Microbiologie médicale
Mahieu, Ludo;  Hôpital universitaire d'Anvers - UIA > Néonatologie
Claeys, G.;  Hôpital universitaire de Gand - RUG > Bactériologie médicale
De Mol, Patrick ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Microbiologie médicale et virologie médicale
Language :
Title :
Towards a Belgian Consensus for prevention of perinatal group B streptococcal disease
Publication date :
October 2002
Event name :
XV Lancefield International Symposium on Streptococci and Streptococcal Diseases (LISSSD)
Event organizer :
Event place :
Goa, India
Event date :
du 6 au 11 octobre 2002
Audience :
Available on ORBi :
since 28 February 2011


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