[en] The two main groups of placental proteins of ruminants are discussed in this paper: chorionic somatomammotropins (placental lactogens) and pregnancy-specific (-associated) proteins. Placental lactogens belong to the prolactin and growth hormone family. They stimulate mammogenesis, fetal growth and maternal metabolism. Pregnancy-specific proteins and pregnancy-associated glycoproteins belong to the aspartic proteinase family like pepsin, cathepsin D and E. These two groups of proteins are secretd in the maternal circulation by the binucleate cells after their migration to and fusion with the uterine cells. Theirs profiles were determined by radioimmunoassay (RIA). Further investigations are in progress to related secretory profiles with alterations of the trophoblastic function such as those occuring in embryonic mortality, abortion, and fetal distress. The endocrine function of the primate and equine palcenta is also discussed.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Beckers, Jean-François ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie de la reproduction
Zarrouk, Anissa; Université de Liège - ULiège - ULG > Physiologie de la Reproduction animale
Batalha, Evie S; Université de Liège - ULiège - ULG > Physiologie de la Reproduction animale
Garbayo, José-Maria; Université de Liège - ULiège - ULG > Physiologie de la Reproduction animale
Mester, L.; University of Veterinary Science, Budapest, Hungary > Dept of Obstetrics and Reproduction
Szenci, Otto; University of Veterinary Science, Budapest, Hungary > Dept of Obstetrics and Reproduction
Language :
English
Title :
Endocrinology of pregnancy: chorionic somatomammotropins and pregnancy-associated glycoproteins: review
Publication date :
July 1998
Journal title :
Acta Veterinaria Hungarica
ISSN :
0236-6290
Publisher :
Akadémiai Kiadó, Budapest, Hungary
Volume :
46
Issue :
2
Pages :
175-189
Peer reviewed :
Peer Reviewed verified by ORBi
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique IRSIA - Institut pour l'Encouragement de la Recherche Scientifique dans l'Industrie et l'Agriculture Spanish Ministry of Agriculture Fisheries and Food Tunisian Ministry of Education
Funding number :
National Research Fund of Hungary (OTKA), Grant no.OTKA T016901
Funding text :
FNRS to J.F. Beckers, Spanish Ministry of Agriculture Fisheries and Food to JM Garbayo, Tunisian Ministry of Eduction to A. Zarrouk and the Hungarian part was supported by the National Research Fund of Hungary (OTKA), Grant no.OTKA T016901
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