[en] This study was designed to test the applicability and the reproducibility of the thermodilution method in the measurement of right ventricular ejection fraction (EF), end-diastolic volume (EDV) and end-systolic volume (ESV) in unsedated cattle. In the 16 healthy calves studied, it was possible, using a fast response thermodilution catheter, to obtain characteristic exponential steplike washout curves, allowing the calculation of right ventricular EF, EDV and ESV. Five to 10 successive thermodilution curves were recorded within a few minutes and two to five similar sets of measurements were performed throughout the same day to test the reproducibility of the technique. The same protocol was repeated the following day. Right ventricular EF, EDV and ESV were reproducible successively, throughout a given day and on following days. The mean intraset, intraday and interdays coefficients of variation ranged from a mean of 4.0 (SD 4.1) per cent to a mean of 18.2 (SD 7.9) per cent. Values of right ventricular volumes and EF agreed with those previously reported in various animal species. Thermodilution was, therefore, shown to be a useful method for measuring with a satisfactory reproducibility, right ventricular EF, EDV and ESV in the unsedated healthy calf
Disciplines :
Anatomy (cytology, histology, embryology...) & physiology Veterinary medicine & animal health
Author, co-author :
Amory, Hélène ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Médecine interne des équidés
Mc Entee, Kathleen ; Université de Liège - ULiège > Département clinique des animaux de compagnie et des équidés > Sémiologie et clinique médicale des petits animaux
Linden, Annick ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Santé et pathologies de la faune sauvage
Desmecht, Daniel ; Université de Liège - ULiège > Département de morphologie et pathologie > Pathologie spéciale et autopsies
Lekeux, Pierre ; Université de Liège - ULiège > Département de sciences fonctionnelles > Physiologie
Language :
English
Title :
Measurement of Right Ventricular Ejection Fraction and Volume by the Thermodilution Technique in the Unsedated Calf
Publication date :
1994
Journal title :
Research in Veterinary Science
ISSN :
0034-5288
eISSN :
1532-2661
Publisher :
British Veterinary Association, London, United Kingdom
Amory, Linden, Desmecht, Rollin, Genicot, Lekeux (1991) Validation of the thermodilution technique for the estimation of the cardiac output in the unsedated calf. Zentralblatt für Veterinärmedizin A 38:409-417.
Bartle, Sanmarco (1966) Comparison of angiocardiographic and thermal washout technics for left ventricular volume measurement. American Journal of Cardiology 18:235-252.
Bing, Heimbecker, Falholt (1951) An estimation of the residual volume of blood in the right ventricle of normal and diseased human hearts in vivo. American Heart Journal 42:483-489.
Braunwald, Ross (1979) Control of cardiac performance. Handbook of Physiology , American Physiological Society, Baltimore, Section 2; 1:533-580.
Bristow, Crislip, Farrehi, Harris, Lewis, Sutherland, Griswold (1964) Left ventricular volume measurements in man by thermodilution. Journal of Clinical Investigation 43:1015-1024.
Brynjolf, Qvist, Mygind, Jordening, Dorph, Munck (1983) Measurement of right and left ventricular ejection fraction in dogs. Clinical Physiology 3:335-348.
Dhainaut, Brunet, Monsallier, Villemant, Devaux, Konno, De Gournay, Armaganidis, Iotti, Huyghebaert, Lanore (1987) Bedside evaluation of right ventricular performance using a rapid computerized thermodilution method. Critical Care Medicine 15:148-152.
Dunlop, Hodgson, Chapman, Grandy, Waldron (1991) Thennodilution estimation of cardiac output at high flows in anesthetized horses. American Journal of Veterinary Research 52:1893-1897.
False, Braunwald (1962) Determination of fraction of left ventricular volume ejected per beat and of ventricular end-diastolic and residual volumes. Experimental and clinical observations with a precardial dilution technic. Circulation 25:674-685.
Gorlin, Rolett, Yurchak, Elliott, Lane, Levy (1964) Left ventricular volume in man by thermodilution. Journal of Clinical Investigation 43:1203-1221.
Hinchcliff, McKeever, Muir (1991) Hemodynamic effects of atropine, dobutamine, nitroprusside, phenylephrine and propranolol in conscious horses. Journal of Veterinary Internal Medicine 5:80-86.
Holt (1956) Estimation of the residual volume of the ventricle of the dog's heart by two indicator dilution technics. Circulation Research 9:187-195.
Holt (1966) Symposium on measurement of left ventricular volume - Part II. Indicator-dilution methods: indicators, injection, sampling and mixing problems in measurement of ventricular volumes. American Journal of Cardiology 18:208-224.
Holt, Rhode, Peoples, Kines (1962) Left ventricular function in mammals of greatly different size. Circulation Research 10:798-806.
Jardin, Gueret, Dubourg, Farcot, Margairaz, Bourdarias (1985) Right ventricular volumes by thennodilution in the adult respiratory distress syndrome. Chest 88:34-39.
Kay, Afshari, Barash, Webler, Iskandrian, Bemis, Hakki, Mundth (1983) Measurement of ejection fraction by thermal dilution techniques. Journal of Surgery Research 34:337-346.
Knowlen, Olivier, Kittleson (1987) Cardiac contractility: a review. Journal of Veterinary Internal Medicine 1:188-198.
Mason, Spann, Zelis (1970) Quantification of the contractile state of the human heart. Maximal velocity of contractile element shortening determined by instantaneous relation between the rate of pressure rise and pressure in the left ventricle during isovolumic systole. American Journal of Cardiology 26:248-257.
O'Grady, Bonagura, Powers, Herring (1986) Quantitative cross-sectional echocardiography in the normal dog. Veterinary Radiology 27:34-49.
Paterrson, Kent, Peirce (1972) A comparison of empiric contractile indices in intact dogs. Cardiology 57:277-294.
Peterson, Skloven, Ludbrook, Uther, Ross (1974) Comparison of isovolumic and ejection phase indices of myocardial performance in man. Circulation 49:1088-1101.
Quinones, Gaasch, Alexander (1976) Influence of acute changes in preload, afterload, contractile state and heart rate on ejection and isovolumic indices of myocardial contractibility in man. Circulation 53:293-302.
Rapaport (1966) Usefulness and limitations of thermal washout techniques in ventricular measurement. American Journal of Cardiology 18:226-234.
Rapaport, Wiegand (1961) Estimation of left ventricular volume by the thermodilution method. Clinical Research 9:85.
Reef (1985) Evaluation of the equine cardio-vascular system. Symposium on cardiology. Veterinary Clinics of North America, Equine Practice 1:275-288.
Rhode, Holt, Kines (1962) The residual volume of the left ventricle of cattle. Physiologist 5:201.
Rolett, Sherman, Gorlin (1964) Measurement of left ventricular volume by thermodilution: an appraisal of technical errors. Journal of Applied Physiology 19:1164-1174.
Sandler (1970) Dimensional analysis of the heart. A review. American Journal of Medical Science 260:56-65.
Searle Linear Models, John Wiley and Sons, New York; 1971.
Seldinger (1953) Catheter replacement of the needle in percutaneous arteriography. Acta Radiologica 39:368-376.
Sisson, Daniel, Twardock (1989) Comparison of left ventricular ejection fraction determined in healthy anesthetized dogs by echocardiography and gated equilibrium radionuclide ventriculography. American Journal of Veterinary Research 50:1840-1847.
Suga, Sagawa (1974) Instantaneous pressure-volume relationships and their ratio in the excised supported canine left ventricle. Circulation Research 35:117-126.
Suga, Sagawa, Shoukas (1973) Load independence of the instantaneous pressure-volume ratio of the canine left ventricle and effects of epinephrine and heart rate on the ratio. Circulation Research 32:314-322.
Tsakiris, Vandenberg, Banchero, Sturm, Wood (1968) Variations of left ventricular enddiastolic pressure volume and ejection fraction with changes in outflow resistance in anesthetized intact dogs. Circulation Research 23:213-222.
Yang, Maranhao, Bentivoglio, Goldberg From Cardiac Catheterization Data to Hemodynamic Parameters, 3rd edn., F. A. Davis Company, Philadelphia; 1988.