Dietary Polyamines and Non-Neoplastic Growth and Disease

[en] This review presents the data that are now available concerning the effects of dietary polyamines at either postnatal or adult stages in non-neoplastic growth and disease. Polyamines provided by food have a potential role in growth and development of the digestive system in neonatal mammals (and fishes). In humans, this property could be of importance in preventing the appearance of food allergies. Dietary polyamines also seem necessary for the maintenance of normal growth and general properties of adult digestive tract. Their possible therapeutic effects have been investigated in gastric, intestinal, and, more recently, whole-body healing.

Disciplines :

Gastroenterology & hepatology

Author, co-author :

Deloyer, Patricia

Peulen, Olivier ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Département des sciences biomédicales et précliniques

Dandrifosse, Guy ; Université de Liège - ULiège > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine)

Language :

English

Title :

Dietary Polyamines and Non-Neoplastic Growth and Disease

Publication date :

September 2001

Journal title :

European Journal of Gastroenterology and Hepatology

ISSN :

0954-691X

eISSN :

1473-5687

Publisher :

Lippincott Williams & Wilkins, United States

Volume :

Issue :

Pages :

1027-32

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

http://ovidsp.tx.ovid.com/spa/ovidweb.cgi?QS2=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

Available on ORBi :

since 30 June 2010

Statistics

Number of views

84 (0 by ULiège)

Number of downloads

2 (2 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenCitations

OpenAlex citations

Bibliography

Bardócz S., Grant G., Brown D.S., Ralph A., Pusztai A. (1993) Polyamines in food - Implications for growth and health. J Nutr Biochem 4:66-71.
Okamoto A., Sugi E., Koizumi Y., Yanagida F., Udaka S. (1997) Polyamine content of ordinary foodstuffs and various fermented products. Biosci Biotech Biochem 61:1582-1584.
Henning S.J. (1981) Postnatal development: Coordination of feeding, digestion, and metabolism. Am J Physiol 241.
Iyngkaran N., Yadav M. (1987) Food allergy. Food Allergy. Immunopathology of the Small Intestine , Marsch MN (editor). New York: John Wiley and Sons Ltd; 415-449.
Luk G.D., Marton L.J., Baylin S.B. (1980) Ornithine decarboxylase is important in intestinal mucosal maturation and recovery from injury in rats. Science 210:195-198.
Dufour C., Dandrifosse G., Forget P.P., Vermesse F., Romain N., Lepoint P. (1988) Spermine and spermidine induce intestinal maturation in the rat. Gastroenterology 95:112-116.
Dandrifosse G., Forget P.P., Romain N., Deloyer P., Wery I. (1991) Early maturation of rat intestine by spermine: Results and prospects. Les Polyamines: Chimie, Biologie, Medecine , Moulinoux JP, Quémener V (editors). Paris: Flammarion (in French); 237-247.
Dandrifosse G., Peulen O., El Khefif N., Deloyer P., Dandrifosse A.C., Grandfils C. (2000) Are milk polyamines preventive agents against food allergy?. Proc Nutr Soc 59:81-86.
Georges P., Dandrifosse G., Vermesse F., Forget P.P., Deloyer P., Romain N. (1990) Reversibility of spermine-induced intestinal maturation in the rat. Dig Dis Sci 35:1528-1536.
Buts J.P., De Keyser N., Kolanowski J., Sokal E., Van Hoof F. (1993) Maturation of villus and crypt cell functions in rat small intestine. Role of dietary polyamines. Dig Dis Sci 38:1091-1098.
Shimizu K., Mushiake S., Yoshimura N., Harada T., Okada S. (1993) The effect of spermine on the disaccharidase activities in suckling rats of different age. Cell Biol Int 17:543-546.
Wild G.E., Daly A.S., Sauriol N., Bennett G. (1993) Effect of exogenously administered polyamine on the structural maturation and enzyme ontogeny of the postnatal rat intestine. Biol Neonate 63:246-257.
Capano G., Bioch K.J., Schriffin E.J., Dascoli J.A., Israel E.J., Harmatz P.R. (1994) Influence of the polyamine, spermidine, on intestinal maturation and dietary antigen uptake in the neonatal rat. J Pediatr Gastroenterol Nutr 19:34-42.
Harada E., Hashimoto Y., Syuto B. (1994) Orally administered spermine induces precocious maturation of macromolecular transport and disaccharidase development in suckling rats. Comp Biochem Physiol A 109:667-673.
Dorhout B., Van Faassen A., Van Beusekom O.M., Kingma A.W., De Hoog E., Nagel G.T. (1997) Oral administration of deuterium-labelled polyamines to sucking rat pups: Luminal uptake, metabolic fate and effects on gastrointestinal maturation. Br J Nutr 78:639-654.
Peulen O., Pirlet C., Klimek M., Dandrifosse G. (1998) Comparison between the natural postnatal maturation and the spermine-induced maturation of the rat intestine. Arch Physiol Biochem 106:46-55.
Ter Steege J.C., Buurman W.A., Forget P.P. (1997) Spermine induces maturation of the immature intestinal immune system in neonatal mice. J Pediatr Gastroenterol Nutr 25:332-340.
Peulen O., Deloyer P., Grandfils C., Loret S., Dandrifosse G. (2000) Intestinal maturation induced by spermine in young animals. Livestock Production Science 66:109-120.
Gréco S., George P., Hugueny I., Louisot P., Biol M.C. (1999) Spermidine-induced glycoprotein fucosylation in immature rat intestine. C R Acad Sci III 322:543-549.
Gréco S., Hugueny I., George P., Perrin P., Louisot P., Biol M.C. (2000) Influence of spermine on intestinal maturation of the glycoprotein glycosylation process in neonatal rats. Biochem J 345:69-75.
Péres A., Cahu G.L., Zambonino Infante J.L. (1997) Dietary spermine supplementation induces maturation in sea bass (Dicentrachus labrax) larvae. Fish Physiol Biochem 16:479-485.
Wéry I., Deloyer P., Dandrifosse G. (1996) Effects of a single dose of orally-administered spermine on the intestinal development of unweaned rats. Arch Physiol Biochem 104:163-172.
Wéry I., Kaouass M., Deloyer P., Buts J.P., Barbason H., Dandrifosse G. (1996) Exogenous spermine induces maturation of the liver in suckling rats. Hepatology 24:1206-1210.
Romain N., Gesell M.S., Leroy O., Forget P.P., Dandrifosse G., Luk G.D. (1998) Effect of spermine administration on pancreatic maturation in unweaned rats. Comp Biochem Physiol A 120:379-384.
Peulen O., Grandfils C., Dandrifosse G. (2000) Maturation of the small intestine is induced by spermine but not by other similar amines. Pflügers Arch - Eur J Physiol 440.
Etienne-Poncin A., Dandrifosse G., Forget P.P., Lepoint A. (1989) Evolution of biochemical characteristics of the intestinal mucosa during the first postnatal weeks in C57 mice. Effects of thyroxine and putrescine. J Pediatr Gastroenterol Nutr 9:375-382.
Deloyer P., Nollet N., Dandrifosse G. (2000) Spermine-induced intestinal maturation in the suckling rat: Effect of prolonged oral treatment. Pflügers Arch - Eur J Physiol 440.
Kaouass M., Deloyer P., Dandrifosse G. (1994) Intestinal development in suckling rats: Direct or indirect spermine action?. Digestion 55:160-167.
Kaouass M., Sulon J., Deloyer P., Dandrifosse G. (1994) Spermine-induced precocious intestinal maturation in suckling rats: Possible involvement of glucocorticoids. J Endocrinol 141:279-283.
Kaouass M., Deloyer P., Gouders I., Peulen O., Dandrifosse G. (1997) Role of interleukin-1 beta, interleukin-6 and TNF alpha in precocious intestinal maturation induced by dietary spermine in suckling rats. Endocrine 6:187-194.
Peulen O., Dandrifosse G. (2000) Cyclosporin A inhibits partially spermine induced differentiation but not cell loss of suckling rat small intestine. Dig Dis Sci 45:750-754.
Kaouass M., Deloyer P., Dandrifosse G. (1997) Involvement of bombesin in spermine-induced corticosterone secretion and intestinal maturation in suckling rats. J Endocdnol 153:429-436.
Romain N., Dandrifosse G., Jeusette F., Forget P.P. (1992) Polyamine concentration in rat milk and food, human milk and infant formulae. Pediatr Res 32:58-63.
Pollack P.F., Koldovsky O., Nishioka K. (1992) Polyamines in human and rat milk and in infant formulas. Am J Clin Nutr 56:371-375.
Buts J.P., De Keyser N., De Raedemaeker L., Collette E., Sokal E.M. (1995) Polyamine profiles in human milk, infant formulas and semi-elemental diets. J Pediatr Gastroenterol Nutr 21:44-49.
Peulen O., Dandrifosse G. Effect of dietary polyamines and amino-acids on polyamines content of the rat milk. Biogenically Active Amines in Food: Metabolism and Physiology , Morgan D, Dandrifosse G (editors). Luxembourg: EC Publication (in press); 6.
Capano G., Bloch K.J., Carter E.A., Dascoli J.A., Schoenfeld D., Harmatz P.R. (1998) Polyamines in human and rat milk influence intestinar cell growth in vitro. J Pediatr Gastroenterol Nutr 27:281-286.
Peulen O., Dewé W., Dandrifosse G., Henrotay I., Romain N. (1998) The relationship between spermine content of human milk during the first postnatal month and allergy in children. Public Health Nutr 1:184-188.
Duchén K., Thorell L. (1999) Nucleotide and polyamine levels in colostrum and mature milk in relation to maternal atopy and atopic development in the children. Acta Paediatr 88:1338-1343.
Smith T.K. (1990) Effect of dietary putrescine on whole body growth and polyamine metabolism. Proc Soc Exp Biol Med 194:332-336.
Smith T.K., Mogridge J.L., Sousadias M.G. (1996) Growth-promoting potential and toxicity of spermidine, a polyamine and biogenic amine found in foods and feed stuffs. J Agric Food Chem 44:518-521.
Sousadias M.G., Smith T.K. (1995) Toxicity and growth-promoting potential of spermine when fed to chicks. J Anim Sci 73:2375-2381.
Grant A.L., Holland R.E., Thomas J.W., King K.J., Liesman J.S. (1989) Effects of dietary amines on the small intestine in calves fed soybean protein. J Nutr 119:1034-1041.
Grant A.L., Thomas J.W., King K.J., Liesman J.S. (1990) Effect of dietary amines on small intestinal variables in neonatal pigs fed soy protein isolate. J Anim Sci 68:363-371.
Mogridge J.L., Smith T.K., Sousadias M.G. (1996) Effect of feeding raw soybeans on polyamine metabolism in chicks and the therapeutic effect of exogenous putrescine. J Anim Sci 74:1897-1904.
Seidel E.R., Haddox M.K., Johnson L.R. (1985) Ileal mucosal growth during intraluminal infusion of ethylamine or putrescine. Am J Physiol 249.
Ginty D.D., Osborne D.L., Seidel E.R. (1989) Putrescine stimulates DNA synthesis in intestinal epithelial cells. Am J Physiol 257.
Wang J.Y., McCormack S.A., Viar M.J., Johnson L.R. (1991) Stimulation of proximal small intestinal mucosal growth by luminal polyamines. Am J Physiol 261.
Jeevanandam M., Holaday N.J., Begay C.K., Petersen S.R. (1997) Nutritional efficacy of a spermidine supplemented diet. Nutrition 13:788-794.
Deloyer P., Dandrifosse G., Bartholomeus C., Romain N., Klimek M., Salmon J. (1996) Polyamines and intestinal properties in adult rats. Br J Nutr 76:627-637.
Deloyer P., Peulen O., Klimek M., Remacle R., Focant C., Dandrifosse G. (1998) Effects of a long-term low-polyamine diet on biochemical parameters and polyamine content in different organs of the germ-free rat. Biogenically Active Amines in Food. Metabolic Effects of Biologically Active Amines in Food , Bardócz S, White A, Hajós G (editors). Luxembourg: EC Publication; 2:130-135.
Löser C., Eisel A., Harms D., Fölsch U.R. (1999) Dietary polyamines are essential luminal growth factors for small intestinal and colonic mucosal growth and development. Gut 44:12-16.
Nandi J., Wright M.V., Fromm D., Ray T.K. (1983) Oral administration of spermine inhibits gastric acid secretion in rats. Dig Dis Sci 28:513-517.
Mizui T., Shimono N., Doteuchi M. (1987) A possible mechanism of protection by polyamines against gastric damage induced by acidified ethanol in rats: Polyamine protection may depend on its antiperoxidative properties. Jpn J Pharmacol 44:43-50.
Wang J.Y., Johnson L.R. (1990) Luminal polyamines stimulate repair of gastric mucosal stress ulcers. Am J Physiol 259.
Brzozowski T., Konturek S.J., Majka J., Dembinski A., Drozdowicz D. (1993) Epidermal growth factor, polyamines, and prostaglandins in healing of stress-induced gastric lesions in rats. Dig Dis Sci 44:276-283.
Konturek P.C., Brzozowski T., Konturek S.J., Szlachcic A., Hahn E.G. (1998) Polyamines and epidermal growth factor in the recovery of gastric mucosa from stress-induced gastric lesions. J Clin Gastroenterol 27.
Luk G.D., Yang P. (1987) Polyamines in intestinal and pancreatic adaptation. Gut 28(SUPPL.):95-101.
Wang J.Y., Johnson L.R. (1992) Luminal polyamines substitute for tissue polyamines in duodenal mucosal repair after stress in rats. Gastroenterology 102:1109-1117.
Buts J.P., De Keyser N., Marandi S., Hermans D., Sokal E.M., Chae Y.H. (1999) Saccharomyces boulardii upgrades cellular adaptation after proximal enterectomy in rats. Gut 45:89-96.
Kummerlen C., Seiler N., Galluser M., Gossé F., Knodgen B., Hasselmann M. (1994) Polyamines and the recovery of intestinal morphology and function after ischemic damage in rats. Digestion 55:168-174.
Chung D.H., Evers B.M., Townsend C.M. Jr., Huang K.F., Herndon D.N., Thompson J.C. (1993) Role of polyamine biosynthesis during gut mucosal adaptation after burn injury. Am J Surg 165:144-149.
Jeevanandam M., Holaday N.J., Begay C.K., Petersen S.R. (1998) Amelioration of the protein metabolic response in spermidine-supplemented trauma rats. Metabolism 47:223-229.
Ter Steege J.C., Forget P.P., Buurman W.A. (1999) Oral spermine administration inhibits nitric oxide-mediated intestinal damage and levels of systemic inflammatory mediators in a mouse endotoxin model. Shock 11:115-119.