[en] The observation that dynamic compliance (Cdyn) tended to rise with respiratory frequency (f) in adult cattle led us to reassess the importance of inertial pressures in measuring Cdyn in large animals. Five healthy Friesian cows were selected for their ability to show an increase of f without significant change in tidal volume (VT). Dynamic compliance was measured three times, both at the resting f (21 +/- 1 cpm), and at higher f (49 +/- 3 cpm), obtained by an artificial increase in the dead space of the breathing mask. Frequency-response characteristics of the measuring instruments were matched up to 12 Hz. The inertia of the lungs and gas stream (In) was calculated as the ratio of the accelerative pressure change to the simultaneous change in volume acceleration. Inertance was also estimated from the dimensions of the bovine airways and from the relative linear flow velocities reported by Rohrer (1915). Dynamic compliance measured during rapid breathing was significantly higher (p less than or equal to 0.01) than base-line values. Dynamic compliance was strongly correlated with f (r = +0.96). Measured and estimated In were 0.002 and 0.003 kPa.sec2.L-1 respectively. Dynamic compliance did not differ significantly from base-line values when it was corrected for the estimated inertance effect.
Disciplines :
Anatomy (cytology, histology, embryology...) & physiology Veterinary medicine & animal health
Author, co-author :
Lekeux, Pierre ; Université de Liège - ULiège > Faculty of Veterinary Medicine - Brussels > Laboratory of Cardio-pulmonary functional investigation
Art, Tatiana ; Université de Liège - ULiège > Faculty of Veterinary Medicine > Laboratory of Cardio-pulmonary functional investigation
Clercx, Cécile ; Université de Liège - ULiège > Faculty of Veterinary Medicine > Laboratory of Cardio-pulmonary functional investigation
Gustin, Pascal ; Université de Liège - ULiège > Faculty of Veterinary Medicine > Laboratory of Cardio-pulmonary functional investigation
Language :
English
Title :
Influence of Inertance on Measurements of the Mechanical Properties of the Bovine Respiratory System
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Bibliography
Barone R. Anatomie comparée des animaux domestiques , Ecole Nationale Vétérinaire, Lyon, France; 1976, 601-755.
Dosman J., Bode F., Urbanetti J., Antic R., Martin R., Macklem P.T. (1975) Role of inertia in the measurement of dynamic compliance. Journal of Applied Physiology 38:64-69.
Dubois A.B., Brody A.W., Lewis D.H., Burgess B.F. (1956) Oscillation mechanics of lungs and chest in man. J Appl Physiol 8:587-594.
Lekeux P., Hajer R., Breukink H.J. (1984) Pulmonary function testing in calves: technical data. American Journal of Veterinary Research 45:342-345.
Lekeux P., Hajer R., Breukink H.J. (1984) Intrathoracic pressure measurement in cattle: standardized procedure. Canadian Journal of Comparative Medicine 48:420-421.
Lekeux P., Hajer R., Breukink H.J. (1984) Effect of somatic growth on pulmonary function values in healthy Friesian cattle. American Journal of Veterinary Research 45:2003-2007.
.
Mead J. (1956) Measurement of inertia of the lungs at increased ambient pressure. J Appl Physiol 9:208-212.
Robinson N.E. (1982) Some functional consequences of species differences in lung anatomy. Advances in Veterinary Science and Comparative Medicine 26:1-33.
Rohrer F. (1915) Der Stomungswiderstand in den menschlichen Atemwegen und der Einfluss der unregelmassigen Verzweigung des Bronchial-systems auf den Atmungsverhauf in verschiedenen Lungenbezirken. Pflugers Archives 162:225-299.
Varene P., Timbal J., Jacquemin (1966) Estimation chez l'homme de l'inertance des gaz ventilés. Comptes rendus de la Société de Biologie 160:523-526.
Woolcock A.N., Mead J., Wohl M.E. (1969) Frequency dependence of compliance as a test for obstruction in small airways. Journal of Clinical Investigation 4:1097-1106.
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