Epidémiologie des adénomes hypophysaires

[fr] Les adénomes hypophysaires représentent une pathologie fréquente parmi les tumeurs cérébrales. Une étude liègoise récente a montré une prévalence des adénomes hypophysaires cliniquement actifs de 1:1064 habitants, nettement supérieure aux données antérieures. Tant dans les séries cliniques qu'autopsiques, les microadénomes à prolactine sont les adénomes prédominants. Les adénomes hypophysaires sont le plus souvent de présentation sporadique, mais des adénomes familiaux dans des formes isolées ou syndromiques sont également décrits. Les adénomes hypophysaires familiaux représentent 5 p.100 des adénomes hypophysaires et leur caractérisation clinique et génétique a été récemment enrichie par la description de la nouvelle entité FIPA (Familial Isolated Pituitary Adenomas) et des mutations du gène AIP (Aryl hydrocarbon receptor-Interactircg Protein). Bien que d'évolution habituellement bénigne, les adénomes hypophysaires sont caractérisés par une grande diversité clinique et génétique qui réclame des moyens diagnostiques et thérapeutiques spécifiques.

Disciplines :

Endocrinology, metabolism & nutrition

Author, co-author :

Burlacu, M. C.

Daly, Adrian ; Université de Liège - ULiège > Département des sciences cliniques > Endocrinologie

Beckers, Albert ; Université de Liège - ULiège > Département des sciences cliniques > Endocrinologie

Language :

French

Title :

Epidémiologie des adénomes hypophysaires

Publication date :

2009

Main work title :

Feuillets de Biologie

Publisher :

Orion, Neuilly-sur-Seine, France

Pages :

29-35 (Vol. 50 - Num. 6)

Available on ORBi :

since 28 June 2010

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Bibliography

Davis JR., WE. Farrell and RN. Clayton : Pituitary tumors. Reproduction 2001, 121 : 363-371.
Faglia G.: Epidemiology and pathogenesis of pituitary adenomas. Acta Endocrinol (Copenh) 1993, 129 Suppl 1: 1-5.
Ezzat S., SL. Asa, WT. Couldwell et al : The prevalence of pituitary adenomas: a systematic review. Cancer 2004, 101 : 613-619.
Daly AE, M. Rixhon, C. Adam et al: High prevalence of pituitary adenomas: a cross-sectional study in the province of Liege, Belgium. J Clin Endocrinol Metab 2006, 91 : 4769-4775.
Ciccarelli A., A. Daly, A. Beckers : The epidemiology of prolactinomas. Pituitary 2005, 8 : 3-6.
Colao A, AD. Sarno, Cappabianca P et al : Gender differences in the prevalence, clinical features and response to cabergoline in hyperprolactinemia. Eur J Endocrinol 2003, 148 : 325-331.
Gillam MP, ME. Molitch, G. Lombardi et al: Advances in the treatment of prolactinomas. Endocr Rev 2006, 27 : 485-534.
Minniti G., V. Esposito, M. Piccirilli et al : Diagnosis and management of pituitary tumours in the elderly : a review based on personal experience and evidence of literature. Eur J Endocrinol 2005, 153 : 723-735.
Colao A : Pituitary tumors in childhood, Chap. 3.In: New Ml (Ed). Pediatric endocrinology, 2004. www.endotext.org).
Petrossians P., W de Herder, D. Kwekkeboom et al: Malignant prolactinoma discovered by D2 receptor imaging. J Clin Endocrinol Metab 2000, 85 : 398-401.
Daly A., MC. Burlacu, E. Livadariu et al : The epidemiology and management of pituitary incidentalomas. Horm Res. 2007, 68 Suppl 5:195-8.
Giirlek A., N. Karavitaki, O. Ansorge et al : What are the marhers of aggressiveness in prolactinomas? Changes in cell biology, extracellular matrix components, angiogenesis and genetics. Eur J Endocrinol 2007, 156 : 143-153.
Ma W, H. Ikeda, T. Yoshimoto : Clinicopathologic study of 123 cases of prolactin-secreting pituitary adenomas with special reference to multihormone production and clonality of the adenomas. Cancer 2002, 95 : 258-266.
Delgrange E., J. Trouillas, D. Maiter et al: Sex-related difference in the growth of prolactinomas: a clinical and proliferation marker study. J Clin Endocrinol Metab 1997, 82 : 2102-2107.
Qian ZR., CC. Li, Yamasaki H et al : Role of E-cadherin, alpha-, beta-, and gamma-catenins, and p120 (cell adhesion molecules) in prolactinoma behavior. Mod Pathol 2002 , 15 : 1357-65.
Kawamoto H., T. Mizoue, K. Arita et al: Expression of epithelial cadherin and cavernous sinus invasion in human pituitary adenomas. J Neurooncol 1997, 34 : 105-109.
Barlier A., JF Vanbellinghen, AF. Daly et al : Mutations in the aryl hydrocarbon receptor interacting protein gene are not highly prevalent among subjects with sporadic pituitary adenomas. J Clin Endocrinol Metab 2007, 92 : 1952-1955.
Nakayama K., N. Ishida, M. Shirane et al : Mice lacking p27 (Kipl) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors. Cell 1996, 85 : 707-720.
Zhang X., GA. Horwitz, AP. Heaney et al : Pituitary tumor transforming gene (PTTG) expression in pituitary adenomas. J Clin Endocrinol Metab 1999, 84 : 761-767.
Van der Lely AJ, A.Beckers, AF. Daly et al : Epidemiology, pathology and complications of acromegaly, pp39-70. In : Acromegaly. Pathology, Diagnosis and Treatment. Taylor & Francis Group, 2005.
Boikos Sa.A., CA. Stratakis : Pituitary pathology in patients with Carney Complex : growth-hormone producing hyperplasia or tumors and their association with other abnormalities. Pituitary 2006, 9: 203-209.
Melmed S.: Medical progress: Acromegaly. N Engl J Med 2006, 355 : 2558-2573.
Landis CA., SB. Masters, A. Spada et al : GTPase inhibiting mutations activate the alpha chain of Gs and stimulate adenylyl cyclase in human pituitary tumours. Nature 1989, 340 : 692-696.
Asa SL., S. Ezzat : Genetics and proteomics of pituitary tumors. Endocrine 2005, 28 : 43-47.
Stevenaert A., G. Perrin, D. Martin et al : Cushing's disease and corticotrophic adenoma: results of pituitary microsurgery. Neurochirurgie 2002, 48 : 234-65.
Selvais P., J. Donckier, M. Buysschaert et al : Cushing's disease: a comparison of pituitary corticotroph microadenomas and macroadenomas. Eur J Endocrinol 1998, 138 : 153-159.
Bertagna X., MC. Raux-Demay, B. Guilhaume et al : Cushing's disease, pp 496-560. In : Melmed S (Ed). The Pituitary. 2nd ed. Blackwell Publishing, 2002.
Ragel BT, Couldwell WT: Pituitary carcinoma: a review of the literature. Neurosurg Focus 2004, 16 : E7.
Georgitsi M., A. Raitila, A. Karhu et al : Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations. Proc Natl Acad Sci USA 2007, 104 : 4101-4105.
Valdes Socin H., P. Chanson, B. Delemer et al: The changing spectrum of TSH-secreting pituitary adenomas: diagnosis and management in 43 patients. Eur J Endocrinol 2003, 48 : 433-442.
Valdes Socin H., A.Daly et A.Beckers : Adenomes hypophysaires thyreotropes, pp 950-953. In : Chanson Ph, Young J (Eds). Traite d'endocrinologie. 1ére ed. Médecine-Sciences, Flammarion, 2007.
Chanson P., S. Brochier et S. Salenave : Adenomes hypophysaires non fonctionnels et adenomes gonadotropes, pp 943-949. In : Chanson Ph, Young J (Eds). Traite d'endocrinologie. 1ére ed. Médecine-Sciences, Flammarion, 2007.
Daneshdoost L., TA. Gennarelli, HM. Bashey et al : Recognition of gonadotroph adenomas in women. N Engl J Med 1991, 324 : 589-594.
Verloes A., A. Stevenaert, BT. Teh et al: Familial acromegaly: case report and review of the literature. Pituitary 1999, 1 : 273-277.
Daly A., ML. Jaffrain-Rea, A. Ciccarelli et al: Clinical charac-terization of familial isolated pituitary adenomas. J Clin Endocrinol Metab 2006, 91 : 3316-3323.
Vierimaa O., M. Georgitsi, R. Lehtonen et al: Pituitary adenoma predisposition caused by germline mutations in the AIP gene. Science 2006, 312 : 1228-1230.
Daly A., JF Vanbellinghen, SK. Khoo et al: Aryl hydrocarbon receptor-interacting protein gene mutations in familial isolated pituitary adenomas: analysis in 73 families. J Clin Endocrinol Metab 2007, 92: 1891-1896.
Luccio-Camelo DC, KN. Une, RE. Ferreira et al : A meiotic recombination in a new isolated familial somatotropinoma kindred. Eur J Endocrinol 2004, 150 : 643-648.
Duerr EM., Chung DC: Molecular genetics of neuroendocrine tumors. Best Pract Res Clin Endocrinol Metab 2007', 21: 1-14.
Poncin J., A. Stevenaert, A. Beckers : Somatic MEN1 gene mutation does not contribute significantly to sporadic pituitary tumorigenesis. Eur J Endocrinol 1999, 140 : 573-576.
Verges B., F. Boureille, P. Goudet et al : Pituitary disease in MEN type 1 (MEN1): data from the France-Belgium MEN1 multicenter study. J Clin Endocrinol Metab 2002, 87 : 457-465.
Pellegata NS., L. Quintanilla-Martinez, G. Keller et al: Germ-line mutations in p27Kipl cause a multiple endocrine neoplasia syndrome in rats and humans. Proc Natl Acad Sci USA 2006, 103 : 15558-15563.
Georgitsi M., A. Raitila, A. Karhu et al: Germline CDKN1B/p27Kipl mutation in multiple endocrine neoplasia. J Clin Endocrinol Metab 2007 May 22 ; (Epub ahead of print)
Ozawa A., SK. Agarwal, CM. Mateo et al: The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kipl mutations. J Clin Endocrinol Metab 2007, 92 : 1948-1951.
Boikos SA., Stratakis CA : Carney complex: the first 20 years. Curr Opin Oncol 2007,19 : 24-29.
Wasniewska M., P. Matarazzo, G. Weber et al : Clinical presentation of McCune-Albright syndrome in males. J Pediatr Endocrinol Metab 2006, 19 Suppl 2 : 619-622.
Beckers A., A. Daly : The clinical, pathological and genetic features of familial isolated pituitary adenomas. Eur J Endocrinol 2007, 157 : 1-13.