[en] Feline herpesvirus 1 (FeHV-1) and feline calicivirus (FCV), associated with upper respiratory tract disease, are highly prevalent in cats worldwide. With the aim to investigate the importance of feline respiratory viruses in a heterogeneous population of cats, samples were taken in a rescue shelter in Liege, Belgium, between March 2005 and August 2006. Reverse transcription polymerase chain reaction (RT-PCR) and polymerase chain reaction (PCR) were performed to diagnose FCV and FeHV-1 infection in the sampled cats. The prevalence rate (33.1%) was higher for FCV than for FeHV-1 (20.1%) whereas prevalence rate of co-infection with both viruses was 10%. Gingivitis was more common in FCV infections (odds ratio (OR)=2.83) whereas respiratory signs were more often observed with FeHV-1 infections. The average age was significantly higher in FCV positive cats (38 months) than in FeHV-1 positive cats (29.9 months). The second and the fourth quarters of the year and the two first quarters were significantly more at risk than the others in the case of FeHV-1 and FCV infection, respectively. Age was found to be a confounding factor. High prevalence of both infections strengthens the importance of applying hygienic and preventive measures in rescue shelters where cats with an unknown status of vaccination are introduced.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Zicola, Angélique ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Virologie, épidémiologie et pathologie des maladies virales
Saegerman, Claude ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Epidémiologie et analyse des risques appl. aux sc. vétér.
Quatpers, Dominique
Viandier, Julie
Thiry, Etienne ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Virologie, épidémiologie et pathologie des maladies virales
Language :
English
Title :
Feline herpesvirus 1 and feline calicivirus infections in a heterogeneous cat population of a rescue shelter.
Bannasch M.J., and Foley J.E. Epidemiologic evaluation of multiple respiratory pathogens in cats in animal shelters. J Feline Med Surg 7 (2005) 109-119
Gaskell R.M., Radford A.D., and Dawson S. Feline infectious respiratory diseases. In: Chandler E.A., Gaskell C.J., and Gaskell R.M. (Eds). Feline medicine and therapeutics. 3rd edn (2004), Blackwell Publishing, Oxford 577-595
Pedersen N.C. Feline herpesvirus type I (feline rhinotracheitis virus). In: Appel M. (Ed). Virus infections of carnivores (1987), Elsevier, Amsterdam 227-237
Gaskell R., Dawson S., Radford A., and Thiry E. Feline herpesvirus. Vet Res 38 (2007) 337-354
Thiry E. Feline viral rhinotracheitis. Clinical virology of the dog and cat (2006), Edition du Point Vétérinaire, Maisons-Alfort 91-97
Gaskell R.M., Dennis P.E., Goddard L.E., Cocker F.M., and Wills J.M. Isolation of felid herpesvirus I from the trigeminal ganglia of latently infected cats. J Gen Virol 66 (1985) 391-394
Gaskell R.M., and Povey R.C. Transmission of feline viral rhinotracheitis. Vet Rec 111 (1982) 359-362
Coyne K.P., Gaskell R.M., Dawson S., Porter C.J., and Radford A.D. Evolutionary mechanisms of persistence and diversification of a calicivirus within endemically infected natural host populations. J Virol 81 (2007) 1961-1971
Radford A.D., Dawson S., Ryvar R., et al. High genetic diversity of the immunodominant region of the feline calicivirus capsid gene in endemically infected cat colonies. Virus Genes 27 (2003) 145-155
Lauritzen A., Jarrett O., and Sabara M. Serological analysis of feline calicivirus isolates from the United States and United Kingdom. Vet Microbiol 56 (1997) 55-63
Scansen B.A., Wise A.G., Kruger J.M., Venta P.J., and Maes R.K. Evaluation of a p30 gene-based real-time reverse transcriptase polymerase chain reaction assay for detection of feline caliciviruses. J Vet Intern Med 18 (2004) 135-138
Sykes J.E., Allen J.L., Studdert V.P., and Browning G.F. Detection of feline calicivirus, feline herpesvirus 1 and Chlamydia psittaci mucosal swabs by multiplex RT-PCR/PCR. Vet Microbiol 81 (2001) 95-108
Willemse M.J., Chalmers W.S., Cronenberg A.M., Pfundt R., Strijdveen I.G., and Sondermeijer P.J. The gene downstream of the gC homologue in feline herpesvirus type 1 is involved in the expression of virulence. J Gen Virol 75 (1994) 3107-3116
Dagnelie P. Statistique théorique et appliquée. Interférence statistique à une et à deux dimensions (1998), De Boeck & Larcier, Bruxelles
Grenier B. Utilisation des ODDS dans les tests associés ou séquenciels. Décicion médicale: analyse et stratégie de la décision dans la pratique médicale (1990), Masson, Paris 102-106
Binns S.H., Dawson S., Speakman A.J., et al. A study of feline upper respiratory tract disease with reference to prevalence and risk factors for infection with feline calicivirus and feline herpesvirus. J Feline Med Surg 2 (2000) 123-133
Coyne M.J., Burr J.H.H., Yule T.D., Harding M.J., Tresnan D.B., and McGavin D. Duration of immunity in cats after vaccination or naturally acquired infection. Vet Rec 149 (2001) 545-548
Pedersen N.C., Sato R., Foley J.E., and Poland A.M. Common virus infections in cats, before and after being placed in shelters, with emphasis on feline enteric coronavirus. J Feline Med Surg 6 (2004) 83-88
Coyne K.P., Dawson S., Radford A.D., et al. Long-term analysis of feline calicivirus prevalence and viral shedding patterns in naturally infected colonies of domestic cats. Vet Microbiol 118 (2006) 12-25
Holst B.S., Berndtsson L.T., and Englund L. Isolation of feline herpesvirus-1 and feline calicivirus from healthy cats in Swedish breeding catteries. J Feline Med Surg 7 (2005) 325-331
Field H.J., Biswas S., Mohammad I.T., et al. Herpesvirus latency and therapy-from a veterinary perspective. Antiviral Res 71 (2006) 127-133
Helps C.R., Lait P., Damhuis A., et al. Factors associated with upper respiratory tract disease caused by feline herpesvirus, feline calicivirus, Chlamydophila felis and Bordetella bronchiseptica in cats: experience from 218 European catteries. Vet Rec 156 (2005) 669-673
Radford A.D., Dawson S., Coyne K.P., Porter C.J., and Gaskell R.M. The challenge for the next generation of feline calicivirus vaccines. Vet Microbiol 117 (2006) 14-18
Coyne K.P., Edwards D., Radford A.D., et al. Longitudinal molecular epidemiological analysis of feline calicivirus infection in an animal shelter: a model for investigating calicivirus transmission within high-density, high-turnover populations. J Clin Microbiol 45 (2007) 3239-3244
Edwards D.S., Coyne K., Dawson S., et al. Risk factors for time to diagnosis of feline upper respiratory tract disease in UK animal adoption shelters. Prev Vet Med 87 (2008) 327-339