Peptides in membranes: tipping the balance of membrane stability.

[en] This review describes a class of peptides that associate with lipids in membranes and are commonly known as 'oblique-orientated peptides'. Owing to an asymmetric distribution of hydrophobic residues along the axis of the alpha-helix, such peptides can destabilize membranes or lipid cores, thereby facilitating such cellular processes as vesicular fusion or protein transport across subcellular compartments, as well as remodelling of lipid cores.

Disciplines :

Biochemistry, biophysics & molecular biology

Author, co-author :

Brasseur, Robert ; Université de Liège - ULiège > Gembloux Agro-Bio Tech

Pillot, T.

Lins, Laurence ; Université de Liège - ULiège > Gembloux Agro-Bio Tech

Vandekerckhove, J.

Rosseneu, M.

Language :

English

Title :

Peptides in membranes: tipping the balance of membrane stability.

Publication date :

1997

Journal title :

Trends in Biochemical Sciences

ISSN :

0968-0004

eISSN :

0167-7640

Publisher :

Elsevier Trends Journals, Cambridge, United Kingdom

Volume :

Issue :

Pages :

167-71
167-71

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 25 June 2010

Statistics

Number of views

50 (6 by ULiège)

Number of downloads

1 (1 by ULiège)

More statistics

Scopus citations^®

128

Scopus citations^®
without self-citations

OpenCitations

Bibliography

White, J. M. (1992) Science 258, 917-924
Zimmerberg, J., Vogel, S. S. and Chernomordik, L. V. (1993) Annu. Rev. Biomol. Struct. 22, 433-466
Horth, M. et al. (1991) EMBO J. 10, 2747-2755
Biezebart, T. et al. (1995) Nature 376, 92-94
Vonèche, V. et al. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 3810-3814
Selkoe, D. J. (1994) Curr. Opin. Neurobiol. 4, 708-716
Pillot, T. et al. (1996) J. Biol. Chem. 271, 28757-28765
Telling, G. C. et al. (1996) Science 274, 2079-2082
Wang, S. et al. (1993) J. Biol. Chem. 268, 1955-1959
Jauhiainen, M. et al. (1993) J. Biol. Chem. 268, 4032-4036
Brasseur, R. (1991) J. Biol. Chem. 266, 16120-16127
Smith, L., Faustinella, C. and Chan, L. (1992) Curr. Opin. Struct. Biol. 2, 490-496
Atkinson, D. and Small, D. M. (1986) Annu. Rev. Biochem. 15, 403-456
Eisenberg, D. et al. (1984) Proc. Natl. Acad. Sci. U. S. A. 81, 140-144
Martin, I. et al. (1993) Biochim. Biophys. Acta 1145, 124-133
Fujii, G., Selsted, M. E. and Eisenberg, D. (1993) Protein Sci. 2, 1301-1312
Jähnig, F. (1990) Trends Biochem. Sci. 15, 93-95
Epand, R. M. et al. (1995) Biopolymers 37, 319-338
Slepushkin, V. A. et al. (1993) Virology 194, 294-301
Epand, R. M. (1993) The Amphipathic Helix, CRC Press
Lear, J. D. et al. (1987) J. Biol. Chem. 262, 6500-6507
Shal, Y. (1995) Trends Biochem. Sci. 20, 460-464
Tatulian, S. A. et al. (1995) EMBO J. 14, 5514-5523
Ishiguro, R. et al. (1996) Biochemistry 35, 4976-4983
Martin, I. et al. (1994) J. Virol. 68, 1139-1148
Izard, J. W. and Kendall, D. A. (1994) Mol. Microbiol. 13, 765-773
Ngsee, J. K., Hansen, W., Walter, P. and Smith, M. (1989) Mol. Cell Biol. 3400-3410
Talmud, P., Lins, L. and Brasseur, R. (1996) Protein Eng. 9, 317-321
Come, J. H., Fraser, P. E. and Landsbury, P. T. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 5959-5963
Huang, Z., Prusiner, S. B. and Cohen, F. E. (1995) Folding Design 1, 13-15
McLaurin, J. and Chakrabartty, A. (1996) J. Biol. Chem. 271, 26482-26489
Weisgraber, K. H. and Mahley, R. W. (1996) FASEB J. 10, 1485-1494
Pillot, T. et al. (1997) Eur. J. Biochem. 243, 650-659
Miyata, M. and Smith, J. D. (1996) Nat. Genet. 14, 55-61
Owens, B. J. et al. (1990) J. Clin. Invest. 86, 1142-1150
Brown, M. S. and Goldstein, J. L. (1986) Science 232, 34-47
Dugl, K. A. et al. (1992) J. Biol. Chem. 267, 25086-25091
Brasseur, R. et al. (1990) Biochim. Biophys. Acta 1043, 245-252
Gallaher, W. R., Segrest, J. P. and Hunter, E. (1992) Cell 70, 531-532
Rapaport, D. and Shai, Y. (1994) J. Biol. Chem. 269, 15124-15131
Benetollo, C. et al. (1996) in Drugs Affecting Lipid Metabolism (Gotto, A. M. et al., eds), pp. 657-662, Elsevier