[en] The current invention concerns novel antiangiogenic peptides which correspond to about 10 to about 150 consecutive amino acids of N-terminal sequences of human growth hormones, human placental lactogen, human growth hormone variant hGH-V, and prolactin, and their use in inhibiting angiogenesis and in the diagnosis of diseases of human pregnancy involving abnormalities of placental vascularization.
Research Center/Unit :
Giga-Cancer - ULiège
Disciplines :
Biochemistry, biophysics & molecular biology
Inventor :
Weiner, Richard I.
Martial, Joseph ; Université de Liège - ULiège > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire
Struman, Ingrid ; Université de Liège - ULiège > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire
Taylor, Robert
Bentzien, Frauke
Language :
English
Title (54) :
Novel antiangiogenic peptide agents and their therapeutic and diagnostic use
Publication date (43-45) :
17 April 2008
Filing date (22) :
19 October 2007
Patent/publication number (10-11) :
US 2008/0090750 A1
Patent status (13) :
B
Priority number (30) :
11/875,308
International classification (IPC) (51) :
A61K 38/00, A61P 43/00, C07K 16/00
European classification (ECLA) (52) :
U.S. Cl. 514/2, 530/300
Applicant (71) :
Weiner R., Martial J., Struman I., Taylor R., Bentzien F.
