[en] Frontal metabolism measured with positron emission tomography is shown to be decreased relatively to that in other cortical or sub-cortical areas, in a population of healthy elderly compared to young volunteers. Cortical atrophy or neuronal depopulation are unlikely to entirely explain this physiological phenomenon, and sub-cortico-cortical deactivation should play a role, analogous to that proposed in subcortical diseases.
Disciplines :
Neurology
Author, co-author :
Salmon, Eric ; Université de Liège - ULiège > Département des sciences cliniques > Neuroimagerie des troubles de la mémoire et révalid. cogn.
Maquet, Pierre ; Université de Liège - ULiège > Centre de recherches du cyclotron
Sadzot, Bernard ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Degueldre, Christian ; Université de Liège - ULiège > Centre de recherches du cyclotron
Lemaire, Christian ; Université de Liège - ULiège > Centre de recherches du cyclotron
Franck, Georges ; Université de Liège - ULiège > Relations académiques et scientifiques (Médecine)
Language :
English
Title :
Decrease of frontal metabolism demonstrated by positron emission tomography in a population of healthy elderly volunteers.
