atomic force microscopy (AFM); molecular recognition; force spectroscopy
Abstract :
[en] The grafting of poly-N-succinimidyl acrylate from scanning probe microscopy tips is shown to be a robust platform for the very easy elaboration of versatile probes with sensor capabilities and tunable properties. The modified tips can be easily postfunctionalized for single-molecule recognition of host-guest and ligand-receptor systems and for the design of smart probes that are thermo- and pH-responsive.
Disciplines :
Materials science & engineering Chemistry
Author, co-author :
Cecchet, Francesca; Université catholique de Louvain (UCL)) > Laboratory for Physics and Chemistry of Polymers (POLY)
Lussis, Perrine ; Université de Liège - ULiège > Department of Chemistry > Nanochemistry and Molecular Systems
Jérôme, Christine ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Gabriel, Sabine ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Silva-Goncalves, Elsa; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Jérôme, Robert ; Université de Liège - ULiège > Department of Chemistry > Center for Education and Research on Macromolecules (CERM)
Duwez, Anne-Sophie ; Université de Liège - ULiège > Department of Chemistry > NanoChemistry and Molecular Systems
Language :
English
Title :
A generic chemical platform for molecular recognition and stimuli-responsive probes based on scanning probe microscopy
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