[en] The purpose of the present study was to screen 27 plant species used in the traditional medicine of Cambodia for in vitro antibacterial and antifungal activities. Thirty-three methanolic extracts were tested against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, Mycobacterium smegmatis and Candida albicans. Screened by disk diffusion assay, the extracts showed antimicrobial activity especially on Gram-positive bacteria. None of the crude methanolic extracts showed activity against P. aeruginosa. Twenty-five selected extracts were evaluated using a micro-dilution test. Harrisonia perforata (roots) and Hymenodictyon excelsum (bark) exhibited a bactericidal effect against S. aureus at a concentration of 500 μg/ml. Azadirachta indica (bark), Harrisonia perforata (roots and stem) and Shorea obtusa (roots) exhibited a bactericidal effect against M. smegmatis at 250 μg/ml.
Disciplines :
Pharmacie, pharmacologie & toxicologie
Auteur, co-auteur :
Chea, Aun; Université de la Méditerrannée
Jonville, Marie ; Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Bun, Sok-Siya; Université de la Méditerrannée
Laget, Michèle; Université de la Méditerrannée
Elias, Riad; Université de la Méditerrannée
Duménil, Gérard; Université de la Méditerrannée
Balansard, Guy; Université de la Méditerrannée
Langue du document :
Anglais
Titre :
In vitro antimicrobial activity of plants used in Cambodian traditional medicine
Date de publication/diffusion :
2007
Titre du périodique :
American Journal of Chinese Medicine
ISSN :
0090-2942
Maison d'édition :
Institute for Advanced Research in Asian Science and Medicine, Garden City, Etats-Unis - New York
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