[en] An efficient system for the analysis of total alkaloids extracted from the aerial parts from different species of genus Hoplophyllum (Rutaceac) by HPLC on a reversed-phase column is described. The HIPLC method described was validated for its specificity, linearity and precision using external standards (haplopine, skimmianine and haplamine). The chromatographic conditions allowed the separation of alkaloids and the quantification of haplopine, skimmianine and haplamine in different samples of species of Haplophyllum collected in Uzbekistan. The alkaloidal contents of samples were compared with their in vitro cytotoxic properties against two cancer cell lines (HeLa. and HCT-116). The cytotoxicity of extracts was correlated with the concentration of haplopine, skimmianine or haplamine in aerial parts of species of Haplophyllum. Copyright (c) 2006 John Wiley
scite shows how a scientific paper has been cited by providing the context of the citation, a classification describing whether it supports, mentions, or contrasts the cited claim, and a label indicating in which section the citation was made.
Bessonova IA. 2000. Acetylhaplophyllidine, a new alkaloid from Haplophyllum perforatum. Chem Nat Comp (Translation of Khim Prir Soedin) 35: 589-590.
Faizutdinova ZS, Bessonova IA, Yunusov SY. 1968. Structures of perforine and haplophyllidine. Khim Prir Soedin 4: 360-367.
Gadi Biala R, Tits M, Wauters JN, Angenot L. 1996. A new HPLC method for the assay of alkaloids in Strychnos nux-vomica and Strychnos ignatii. Fitoterapia 67: 163-165.
Graham JG, Quinn ML, Fabricant DS, Farnsworth NR. 2000. Plants used against cancer - an extension of the work of Jonathan Hartwell. J Ethnopharmac 73: 347-377.
Jansen O, Akhmedjanova V, Angenot L, Balansard G, Chariot A, Ollivier E, Tits M, Frederich M. (2006) Screening of fourteen alkaloids isolated from Haplophyllum A. Juss. for their cytotoxic properties. J Ethnopharmac 105: 241-245.
Prakash Chaturvedula VS, Schilling JK, Miller JS, Andriantsiferana R, Rasamison VE, Kingston DG. 2003. New cytotoxic alkaloids from the wood of Vepris punctata from the Madagascar. J Nat Prod 66: 532-534.
Rasulova Kh A, Bessonova IA. 1992. Alkaloids of Haplophyllum perforatum. Khim Prir Soedin 2: 249-251.
Townsend CC. 1986. Taxonomic revision of the genus Haplophyllum (Rutaceae). Hooker's Icones Plantarium. Bentham-Moxon Trust 40: 336.
Yunusov SY, Sidyakin GP. 1955. Alkaloids of Haplophyllum species II. Zhur Obshchei Khimii 25: 2009-2016.
Similar publications
Sorry the service is unavailable at the moment. Please try again later.
This website uses cookies to improve user experience. Read more
Save & Close
Accept all
Decline all
Show detailsHide details
Cookie declaration
About cookies
Strictly necessary
Performance
Strictly necessary cookies allow core website functionality such as user login and account management. The website cannot be used properly without strictly necessary cookies.
This cookie is used by Cookie-Script.com service to remember visitor cookie consent preferences. It is necessary for Cookie-Script.com cookie banner to work properly.
Performance cookies are used to see how visitors use the website, eg. analytics cookies. Those cookies cannot be used to directly identify a certain visitor.
Used to store the attribution information, the referrer initially used to visit the website
Cookies are small text files that are placed on your computer by websites that you visit. Websites use cookies to help users navigate efficiently and perform certain functions. Cookies that are required for the website to operate properly are allowed to be set without your permission. All other cookies need to be approved before they can be set in the browser.
You can change your consent to cookie usage at any time on our Privacy Policy page.