Reference : Kinetics of circulating antigens in pigs experimentally infected with Taenia solium eggs
Scientific journals : Article
Life sciences : Phytobiology (plant sciences, forestry, mycology...)
Life sciences : Veterinary medicine & animal health
Life sciences : Entomology & pest control
Kinetics of circulating antigens in pigs experimentally infected with Taenia solium eggs
Nguekam, A. [> > > >]
Zoli, A. P. [> > > >]
Vondou, L. [> > > >]
Pouedet, S. M. R. [> > > >]
Assana, E. [> > > >]
Dorny, P. [> > > >]
Brandt, J. [> > > >]
Losson, Bertrand mailto [Université de Liège - ULiège > Département des maladies infectieuses et parasitaires > Parasitologie et pathologie des maladies parasitaires >]
Geerts, S. [> > > >]
Veterinary Parasitology
Elsevier Science Bv
Yes (verified by ORBi)
[en] pig-cestoda ; Taenia solium ; cysticercosis ; ELISA ; experimental infection ; circulating antigen
[en] Three groups of four piglets were experimentally infected with different doses (10(3), 10(4) and 10(5)) of Taenia solium eggs whereas a fourth group of two pigs received gravid proglottids. At autopsy 6 months post infection, the two latter pigs were heavily infected with more than 3000 living cysts per kg of muscle. Ten of the 12 other pigs harboured light infections, i.e. between 2 and 107 cysticerci, 42.4% of which were degenerated. The two remaining pigs had no detectable cysts at post mortem examination. Circulating antigens (CA) were detected in the sera of all pigs harbouring living cysticerci using a monoclonal antibody based ELISA. CA were first detected between 2 and 6 weeks post infection and remained present generally throughout the entire observation period even in pigs carrying only five to eight living cysts, although strong fluctuations of the level of CA were observed in some pigs. In animals without living cysts at post mortem CA were only detected for a short period and disappeared presumably when the cysticerci became degenerated. The minimum number of living cysts, which could be detected using this ELISA, was 1. (C) 2002 Elsevier Science B.V. All rights reserved.

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