Reference : Lhermitte-Duclos disease
Scientific journals : Article
Human health sciences : Neurology
Social & behavioral sciences, psychology : Neurosciences & behavior
http://hdl.handle.net/2268/40239
Lhermitte-Duclos disease
English
Reznik, M. [> >]
Schoenen, Jean mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Neuro-anatomie >]
1983
Acta Neuropathologica
Springer Verlag
59
2
88-94
Yes (verified by ORBi)
International
0001-6322
1432-0533
New York
NY
[en] Adult ; Cerebellar Cortex/pathology ; Cerebellar Neoplasms/pathology/radiography/ultrastructure ; Ganglioneuroma/pathology/radiography/ultrastructure ; Humans ; Male ; Neurons/pathology ; Tomography, X-Ray Computed
[en] A new case of Lhermitte-Duclos disease (dysplastic gangliocytoma of the cerebellum) was recognized in an adult man after neurosurgery. Conventional, Golgi, and electron-microscopic investigations support the view that this rare lesion results from a progressive hypertrophy of granular cell neurons with excess of myelination of their axons in the molecular layer while inducing the local disappearance of Purkinje cells and the central core of the cerebellar folia. After a follow-up of 4 years, the patient now leads a normal life; no recurrence has occurred and no other neuropathologic alteration have been detected.
http://hdl.handle.net/2268/40239

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