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Article (Scientific journals)
Mazindol in the treatment of Parkinson's disease.
Delwaide, P. J.; Schoenen, Jean; Martinelli, P.
1983In Archives of Neurology, 40 (13), p. 788-90
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Keywords :
Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indoles/therapeutic use; Male; Mazindol/therapeutic use; Parkinson Disease/drug therapy; Pilot Projects
Abstract :
[en] Mazindol, a drug that blocks the reuptake of dopamine, was studied in the treatment of Parkinson's disease in both a pilot study (12 patients) and a controlled trial (11 patients). The patients had stage II or III disease, according to the classification of Hoehn and Yahr. Both studies showed that mazindol possessed anti-parkinsonian properties and that the improvement was statistically significant. The therapeutic effect was moderate, but could be of value for patients in the early stages of the disease. The drug was well tolerated; only two patients had side effects.
Disciplines :
Neurology
Neurosciences & behavior
Author, co-author :
Delwaide, P. J.
Schoenen, Jean  ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Neuro-anatomie
Martinelli, P.
Language :
English
Title :
Mazindol in the treatment of Parkinson's disease.
Publication date :
1983
Journal title :
Archives of Neurology
ISSN :
0003-9942
eISSN :
1538-3687
Publisher :
American Medical Association, Chicago, United States - Illinois
Volume :
40
Issue :
13
Pages :
788-90
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 24 February 2010

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