Reference : The Epidemiology of Prolactinomas
Scientific journals : Article
Human health sciences : Endocrinology, metabolism & nutrition
http://hdl.handle.net/2268/37185
The Epidemiology of Prolactinomas
English
Ciccarelli, A. [ > > ]
Daly, Adrian [> > > >]
Beckers, Albert mailto [Université de Liège - ULiège > Département des sciences cliniques > Endocrinologie]
Jan-2005
Pituitary
Springer
8
1
3-6
Yes (verified by ORBi)
International
1386-341X
Netherlands
[en] prolactin ; prolactinoma ; pituitary ; tumor ; inherited ; neoplasm ; epidemiology
[en] Prolactin-secreting tumors (prolactinomas), the most frequently occurring pituitary tumor, have a frequency that varies with age and sex. They occur most frequently in females aged 20 to 50 years old, at which time the female-to-male ratio is approximately 10:1. In the pediatric-adolescent age group, prolactinomas have a prevalence of 100/million population, and account for less than 2% of all intracranial tumors. Prolactinomas occur in approximately 30% of patients with multiple endocrine neoplasia type 1 and in this setting, they may be more aggressive than their sporadic counterparts. Patients with Carney complex or McCune-Albright syndrome may exhibit hyperprolactinemia due to a pituitary tumor derived from somatomammotropic cells that secrete both growth hormone and prolactin. Few familial cases of prolactinoma unrelated to MEN-1 are reported in literature.
Researchers ; Professionals
http://hdl.handle.net/2268/37185
10.1007/s11102-005-5079-0

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