astrocytes proliferation; regulation of proliferation; neural cell culture
Abstract :
[en] In this work, we report the preliminary characterization and purification of astrostatine, a protein secreted by neuronal cells in culture and which inhibits type 1 astrocytes proliferation. This protein of a low molecular weight (14 kDa) is not active on glioma cell lines but is released by normal or tumoral neurons in culture.
Rogister, Bernard ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine
Language :
French
Title :
Caractérisation et purification préliminaires de l'Astrostaine, une protéine neuronale inhibant la prolifération des astrocytes de type 1
Alternative titles :
[en] Characterization and preliminary purification of astrostatine, a neuronal protein inhibiting type 1 astrocytes proliferation