The importance of liposomes as models and tools in the understanding of photosensitization mechanisms

[en] The various applications of liposomes in understanding photosensitization are described in this paper, with particular emphasis on the various kinds of information that these models allow to obtain in phototherapy. Liposomes are simple vesicles in which an aqueous phase is enclosed by a phospholipidic membrane. They are suitable models mimicking specific situations occurring <br />m vivo and they allow study of the influence of physieochemieal, photobioiogieal and biochemical factors on the uptake of photosensitizers by tissues, their mechanisms of action and the subsequent photoinduced tumor necrosis. Moreover, solubilization of the sensitizer into the bilayer seems to improve its tumoral selectivity and its photodynamic efficiency.

Disciplines :

Physics

Author, co-author :

Hoebeke, Maryse ; Université de Liège - ULiège > Département de physique > Spectroscopie biomédicale

Language :

English

Title :

The importance of liposomes as models and tools in the understanding of photosensitization mechanisms

Publication date :

1995

Journal title :

Journal of Photochemistry and Photobiology B: Biology

ISSN :

1011-1344

Publisher :

Elsevier Science, Lausanne, Switzerland

Volume :

Issue :

Pages :

189-196

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 13 May 2010

Statistics

Number of views

59 (8 by ULiège)

Number of downloads

1 (1 by ULiège)

More statistics

Scopus citations^®

Scopus citations^®
without self-citations

OpenCitations

OpenAlex citations

Bibliography

Rickwood, Hames (1990) Liposomes: a pratical approach. Practical Approach Series, Oil Press at Oxford University Press, Oxford; .
Gregoriadis (1984) Preparation of liposomes. Liposome technology , CRC Press, Boca Raton, FL; 1.
Gregoriadis (1984) Incorporation of drugs, proteins and genetic material. Liposome technology , CRC Press, Boca Raton, FL; 2.
Cullis, Hope, Bally, Madden, Mayer, Janoff (1987) Liposomes as pharmaceuticals. Liposomes from biophysics to therapeutics , M. Ostro, Marcel Dekker, New York, NY; 39-73.
Gruner (1987) Materials properties of liposomal bilayers. Liposomes from biophysics to therapeutics , M. Ostro, Marcel Dekker, New York, NY; 1-39.
Gregoriadis (1984) Targeted drug delivery and biological interaction. Liposome technology , CRC Press, Boca Raton, FL; 3.
Kaye, Richardson (1979) Potential of liposomes as drug-carriers in cancer chemotherapy: a review. Cancer Chemother. Pharmacol. 3:81-85.
Valenzeno (1987) Photomodification of biological membranes with emphasis on singlet oxygen mechanisms. Photochem. Photobiol. 46:146-160.
Kreuter (1991) Liposomes and nanoparticles as vehicles for antibiotic. Infection 19(4):224-228.
Lopez-Berestein, Bodey, Frankel, Mehta (1987) Treatment of hepatosplenic fungal infections with liposomal amphotericin. Br. J. Clin. Oncol. 5:310-317.
Hagiwara, Takahashi, Oku (1989) Cancer chemotherapy administered by activated carbon particles and liposomes. CRC Crit. Rev. Oncology/Hematology 9:319-350.
Oku (1991) Liposomes. Polymeric drugs and drug delivery systems , R. Dunn, R. Ottenbrite, ACS Symposium Series; 469:24-33.
Oku, Namba, Okada (1992) Tumor accumulation of novel RES-avoiding liposomes. Biochem. Biophys. Acta 1126:255-260.
Korbelik (1991) Photosensitizers in photodynamic therapy. Period. Biol. 93:563-574.
Pidgeon, Hunt (1983) Light sensitive liposomes. Photochemistry and Photobiology 37:491-494.
Dougherty, Boyle, Weishaupt, Hendersen, Potter, Bellnier, Wityk (1983) Photoirradiation therapy — clinical and drug advances. Porphyrin photosensitization , D. Kessel, T. Dougherty, Plenum, New York, NY; 15-21.
Dolphin (1994) Photomedicine and photodynamic therapy. Can. J. Chem. 72:1005-1013.
Gibson, Murant, Hilf (1987) Photosensitizing effects of hematoporphyrin derivative immobilized on sepharose. Photochem. Photobiol. 45:93-104.
Ricchelli, Jori, Gobbo, Trochin (1991) Liposomes as models to study the distribution of porphyrins in cell membranes. Biochim. Biophys. Acta 1065:42-48.
Grand, Gasparro (1993) Present and future uses of photochemotherapy in medicine. The Spectrum 6:28-30.
Sieber (1987) Elimination of residual tumor cells from autologous bone marrow grafts by dye-mediated photolysis: preclinical data. Photochem. Photobiol. 46:71-76.
Plant (1986) Mechanism of concentration quenching of xanthone dye encapsulated in phospholipid vesicle. Photochem. Photobiol. 44:453-459.
Sekher, Garbo (1993) Spectroscopic studies of tin ethyl etiopurpurin in homogeneous and heterogeneous systems. J. Photochem. Photobiol.: Biol. 20:117-125.
Cools, Janssen (1986) Fluorescence response of acridine orange to changes in pH gradients across liposome membranes. Experientia 42:954-956.
Valduga, Reddi, Jori (1987) Spectroscopic studies on Zn(II)-phthalocyanine in homogeneous and microheterogeneous systems. J. Inorg. Biochem. 29:59-65.
Ricchelli, Stevanin, Jori (1988) Porphyrin-liposome interactions: influence of the physicochemical properties of the phospholipid bilayer. Photochem. Photobiol. 48:13-18.
Aramendia, Krieg, Nitsh, Bittersmann, Braslavsky (1988) The photophysics of Merocyanine 540. A comparative study in ethanol and in liposomes. Photochem. Photobiol. 48:187-194.
Ehrenberg, Pevzener (1993) Spectroscopic properties of the potentiometric Merocyanine 540 in solutions and liposomes. Photochemistry and Photobiology 57:228-234.
Williamson, Mattocks, Schlegel (1983) Merocyanine 540, a fluorescent probe sensitive to lipid packing. Biochim. Biophys. Acta 732:387-393.
Copeland, Alving, Grenan (1976) Light-induced leakage of spin label marker from liposomes in the presence of phototoxic phenothiazines. Photochem. Photobiol. 24:41-48.
Biolo, Jori, Soncin, Pratasi, Vanni, Richter, Kenney, Rodgers (1994) Photodynamic therapy of B16 pigmented melanoma with liposome-delivered Si(IV)-naphthalocyanine. Photochem. Photobiol. 59:362-365.
Ricchelli, Gobbo, Jori, Morena, Vinzeno, Salet (1993) Photosensitization of mitochondria by liposome-bound porphyrins. Photochem. Photobiol. 58:53-58.
Chowdhary, Green, Morgan (1993) Dye-sensitized destabilization of liposomes bearing photo-oxidizable lipid head groups. Photochem. Photobiol. 58:362-366.
Grossweiner, Grossweiner (1982) Hydrodynamic effects in the photosensitized lysis of liposomes. Photochemistry and Photobiology 35:583-586.
Grossweiner, Goyal (1983) Photosensitized lysis of liposomes by hematoporphyrin derivative. Photochemistry and Photobiology 37:523-532.
Gross, Ehrenberg, Johnson (1993) Singlet oxygen generation by porphyrins and the kinetics of 9,10-dimethylanthracene photosensitization in liposomes. Photochem. Photobiol. 57:808-813.
Emiliani, Delmelle (1983) The lipid solubility of porphyrins modulates their phototoxicity in membrane models. Photochemistry and Photobiology 37:487-490.
Gibson, Hilf (1985) Interdependence of fluence, drug dose and oxygen on hematoporphyrin derivative induced photosensitization of tumor mitochondria. Photochem. Photobiol. 42:367-373.
Gibson, Cohen, Hilf (1984) Evidence against the production of superoxide by photoirradiation of hematoporphyrin derivative. Photochem. Photobiol. 40:441-448.
Gottfried, Peled, Winkelman, Kimel (1988) Photosensitizers in organized media: singlet oxygen production and spectral properties. Photochem. Photobiol. 48:157-163.
Muller-Runkel, Blais, Grossweiner (1984) Photodynamic damage to egg lecithin liposomes. Photochemistry and Photobiology 33:683-687.
Grossweiner, Patel, Grossweiner (1982) Type I and Type II mechanisms in the photosensitized lysis of phosphatidylcholine liposomes by hematoporphyrin. Photochem. Pothobiol. 36:159-167.
Sentil, Jones, Senthil, Grossweiner (1994) Hypericin photosensitization in aqueous model systems. Photochemistry and Photobiology 59:40-47.
Hoebeke, Seret, Piette, Van de Vorst (1993) Destruction of stearic acid nitroxyl radicals mediated by photoexcited Merocyanine 540 in liposomal and micellar systems. Biochemistry 32:2730-2736.
Hoebeke, Enescu, Lindqvist (1994) Quenching of Merocyanine 540 triplet state by nitroxyl radicals in liposomal systems: a laser flash photolysis study. J. Photochem. Photobiol. B: Biol. 22:229-233.
Hoebeke, Piette, Van de Vorst (1991) Photosensitized production of singlet oxygen by merocyanine 540 bound to liposomes. J. Photochem. Photobiol. B: Biol. 9:281-284.
Rodgers, Bates (1982) A laser flash kinetic spectrophotometric examination of the dynamics of singlet oxygen in unilamellar vesicles. Photochemistry and Photobiology 35:473-478.
Rodgers (1983) Time resolved studies of the 1.27 μm luminescence from singlet oxygen generated in homogeneous and in microheterogeneous fluids. Photochem. Photobiol. 37:99-103.
Lindig, Rodgers (1981) Rate parameters of the quenching of singlet oxygen by water soluble and lipid soluble substrates in aqueous and micellar systems. Photochemistry and Photobiology 33:627-634.
Dearden (1986) Kinetics of 1O2 (1Δg) photooxidation reactions in egg-yolk lecithin vesicles. J. Chem. Soc., Faraday Trans. 1 82:1627-1635.
Krieg (1993) Determination of. J. Biochem. Biophys. Methods 27:143-149.
Nonell, Braslavsky, Schaffner (1990) Quantum yield of production of singlet molecular oxygen in aqueous dispersions of small unilamellar lipid vesicles. A time-resolved near-IR phosphorescence study. Photochem. Photobiol. 51:551-556.
Feix, Kalyanaraman, Chignell, Hall (1988) Direct observation of singlet oxygen production by Merocyanine 540 associated with phosphatidylcholine liposomes. J. Biol. Chem. 263:17247-17250.
Blan, Grossweiner (1987) Singlet oxygen generation by furocoumarins effect of DNA and liposomes. Photochemistry and Photobiology 45:117-183.
Kalyanaraman, Feix, Sieber, Thomas, Girotti (1987) Photodynamic action of Merocyanine 540 on artificial and natural cell membranes: involvement of singlet molecular oxygen. Proc. Natl. Acad. Sci. USA 84:2999-3003.
Kim, Jung (1992) Iron-sulfur centers as endogenous blue light sensitizers in cells: a study with an artificial non-heme iron protein. Photochem. Photobiol. 56:63-68.
Mc Rae, Yamamoto, Neil Towers (1985) The mode of action of polyacetylene and thiophene photosensitizers on liposome permeability to glucose. Biochimica et Biophysica Acta (BBA) - Biomembranes 821:488-496.
Hadjur, Jeunet, Jardon (1994) Photosensitization by hypericin electron spin resonance (ESR) evidence for the formation of singlet oxygen and superoxide anion radicals in an in vitro model. Journal of Photochemistry and Photobiology B: Biology 26:64-67.
Feix, Kalyanaraman (1991) Production of singlet oxygen-derived hydroxyl radical adducts during Merocyanine-540 mediated photosensitization: analysis by ESR-spin trapping and HPLC with electrochemical detection. Arch. Biochem. Biophys. 291:43-51.
Feix, Kalyanaraman (1991) An electron spin resonance study of Merocyanine 540-mediated Type I reactions in liposomes. Photochem. Photobiol. 53:39-45.
Lipson, Baldes, Obsen (1961) The use of a derivative of hematoporphyrin in tumor detection. J. Natl. Cancer Inst. 26:1-8.
Dougherty (1984) Photodynamic therapy of malignant tumors. Crit. Rev. Oncol./Hematol. 2:83-116.
Ehrenberg, Gross (1988) The effect of liposomes' membrane composition on the binding of the photosensitizers HpD and photofrin II. Photochem. Photobiol. 48:461-466.
Kessel (1977) Effects of photoactivated porphyrins at the cell surface of leukemia L1210 cells. Biochemistry 16:3443-3449.
Kessel, Chou (1983) Tumor-localizing components of the porphyrin preparation hematoporphyrin derivative. Cancer Res. 43:1994-1999.
Ehrenberg, Malik, Nitzan (1985) Fluorescence spectral changes of hematoporphyrin derivative upon binding to the lipid vesicle. Staphylococcus aureus and Escherichia coli. Photochem. Photobiol. 41:429-435.
Seeman, Roth, Schneider (1971) The membrane concentrations of alcohol anesthetics. Biochim. Biophys. Acta 225:171-184.
Emiliani, Delmelle, Cannistraro, Van de Vorst (1983) Solubility of hematoporphyrin and photodynamic damages in liposomal systems: optical and electron spin resonance studies. Photochem. Photobiol. 5:119-128.
Gross, Ehrenberg (1989) The partition and distribution of porphyrins in liposomal membranes. A spectroscopic study. Biochim. Biophys. Acta 983:118-122.
Van Blitterswijk (1984) Alteractions in lipid fluidity in the plasma membrane of tumor cells. Membrane fluidity , M. Shinitzky, CRC Press, Boca Raton, FL; 53-83.
Gross, Malik, Ehrenberg (1987) Effects of membrane physical parameters on hematoporphyrin-derivative binding to liposome: a spectroscopy study. J. Membr. Biol. 97:215-221.
Williamson, Mattocks, Schlegel (1983) Merocyanine 540, a fluorescent probe sensitive to lipid packing. Biochim. Biophys. Acta 732:387-393.
Ricchelli, Jori (1986) Distribution of porphyrins in the various compartments of unilamellar liposomes of dipalmitoyl-phosphatidylcholine as probed by fluorescence spectroscopy. Photochem. Photobiol. 44:151-157.
Schmidt (1983) Further photophysical and photochemical characterization of flavins associated with single-shelled vesicles. J. Membr. Biol. 76:73-82.
Strzalka, Gruszecki (1994) Effect of β-carotene on structural and dynamic properties of model phosphatidylcholine membrane. I. An EPR spin label study. Biochim. Biophys. Acta 1194:138-142.
Jezowska, Wolak, Gruszecki, Strzalka (1994) Effect of β-carotene on structural and dynamic properties of model phosphatidylcholine membrane. II. A 31P-NMR and 13C-NMR study. Biochim. Biophys. Acta 1194:143-148.
Mayhew, Vaughan, Panus, Murray, Henderson (1993) Lipid-associated methylpheophorbide-A (hexyl-ether) as a photodynamic agent in tumor-bearing mice. Photochem. Photobiol. 58:845-851.
Ricchelli, Jori (1985) Spectroscopic studies on the intraliposomal distribution of porphyrins. Photodynamic Therapy of Tumors and Other Diseases , G. Jori, C. Perria, Libreria Progetto, Padova; 85-87.
Wöhrle, Shopova, Müller, Milev, Mantareva, Krastev (1993) Liposome-delivered Zn(II)-23-naphthalocyanines as potential sensitizers for PDT synthesis photochemical pharmacokinetic and phototherapeutic studies. Journal of Photochemistry and Photobiology B: Biology 21:155-165.
Reddi, Lo Castr, Biolo, Jori (1987) Pharmacokinetic studies with Zinc (II) phthalocyanine in tumor-bearing mice. Br. J. Cancer 56:597-600.
Peterson, Masquelier, Rudling, Söderberg, Vitols (1991) Lipoproteins, malignancy and anticancer agents. Lipoproteins as Carriers of Pharmacological Agents , J.M. Shaw, Marcel Dekker, New York, NY; 175-200.
Korbelik (1992) Low density lipoprotein receptor pathway in the delivery of Photofrin: how much is relevant for selective accumulation of the photosensitizer in tumors?. J. Photochem. Photobiol. B: Biol. 12:107-109.
Kessel (1992) The role of low density lipprotein in the biodistribution of photosensitizing agents. J. Photochem. Photobiol.: B: Biol. 14:261-262.
Richter, Waterfield, Jain, Canaam, Allison, Levy (1993) Liposomal delivery of a photosensitizer, Benzoporphyrin derivative monoacid ring A (BPD), to tumor tissue in mouse tumor model. Photochem. Photobiol. 57:1000-1006.
Jori, Reddi, Cozzani, Tomoi (1986) Controlled targetting of different subcellular sites by porphyrins in tumor-bearing mice. Br. J. Cancer 53:615-621.
Andreoni, Cubeddu, Jori, Laporta, Reddi (1983) Time-resolved fluorescence studies of hematoporphyrin in different solvent systems. Z. Naturforsch. 38:83-89.
Keene, Kessel, Land, Redmont, Truscott (1986) Direct detection of singlet oxygen sensitized by haematoporphyrin and related compounds. Photochem. Photobiol. 43:117-120.
Cozzani, Jori, Bertoloni, Milanesi, Sicuro (1985) Efficient photosensitization of malignant human cells in vitro by liposome-bound porphyrins. Chem. Biol. Interact. 53:131-143.
Zhou, Milanesi, Jori (1988) An ultrastructural comparative evaluation of tumors photosensitized by porphyrins administrated in aqueous solution, bound to liposomes or to lipoproteins. Photochem. Photobiol. 48:487-492.
Woodburn, Chang, Lee, Henderson, Kessel (1994) Biodistribution and PDT efficacy of a ketochlorin photosensitizer as a function of the delivery vehicle. Photochem. Photobiol. 60:154-159.
Kessel, Garbo, Hampton (1993) The role of lipoproteins in the distribution of Tin etiopurpurin (Sn ET2) in the tumorbearing rat. Photochem. Photobiol. 57:298-301.
Rensen, Love, Taylor (1994) In vitro interaction of Zinc (II)-phthalocyanine-containing liposomes and plasma lipoproteins. J. Photochem. Photobiol. B, Biol. 26:29-35.
Morgan, Thomas, Sandhy, Yianni, Mitchell (1987) Light-induced fusion of liposomes with release of trapped marker dye is sensitized by photochromic phospholipid. Biochim. Biophys. Acta 903:504-509.