Reference : Creatine kinase isoenzymes in severe head injury.
Scientific journals : Article
Human health sciences : Laboratory medicine & medical technology
Creatine kinase isoenzymes in severe head injury.
Hans, Pol [Centre Hospitalier Universitaire de Liège - CHU > > Anesthésie et réanimation >]
Born, J. D. [> > > >]
Chapelle, Jean-Paul mailto [Université de Liège - ULiège > Département de pharmacie > Chimie médicale >]
Milbouw, G. [> > > >]
Journal of Neurosurgery
American Association of Neurological Surgeons
Yes (verified by ORBi)
[en] Adolescent ; Adult ; Brain Injuries/enzymology ; Child ; Child, Preschool ; Coma/enzymology ; Creatine Kinase/blood/cerebrospinal fluid ; Female ; Humans ; Infant ; Intracranial Pressure ; Isoenzymes ; Male ; Middle Aged
[en] Brain-type creatine kinase (CK) isoenzyme (CK-BB) was found in the ventricular cerebrospinal fluid (CSF) and the serum in a series of 35 patients within 13 hours following severe head injury. There was a good correlation between total CK and CK-BB activities in CSF only. The values found in the CSF appear to be a quantitative index of brain dysfunction at admission, and did not correlate with intracranial pressure activity. High levels of CK-BB in the CSF correlated with a poor outcome, and thus offer a reliable criterion for the assessment of the severity of head injury.

There is no file associated with this reference.

Bookmark and Share SFX Query

All documents in ORBi are protected by a user license.