Reference : Creatine kinase isoenzymes in severe head injury.
Scientific journals : Article
Human health sciences : Laboratory medicine & medical technology
http://hdl.handle.net/2268/34843
Creatine kinase isoenzymes in severe head injury.
English
Hans, Pol [Centre Hospitalier Universitaire de Liège - CHU > > Anesthésie et réanimation >]
Born, J. D. [> > > >]
Chapelle, Jean-Paul mailto [Université de Liège - ULiège > Département de pharmacie > Chimie médicale >]
Milbouw, G. [> > > >]
1983
Journal of Neurosurgery
American Association of Neurological Surgeons
58
5
689-92
Yes (verified by ORBi)
International
0022-3085
Charlottesville
VA
[en] Adolescent ; Adult ; Brain Injuries/enzymology ; Child ; Child, Preschool ; Coma/enzymology ; Creatine Kinase/blood/cerebrospinal fluid ; Female ; Humans ; Infant ; Intracranial Pressure ; Isoenzymes ; Male ; Middle Aged
[en] Brain-type creatine kinase (CK) isoenzyme (CK-BB) was found in the ventricular cerebrospinal fluid (CSF) and the serum in a series of 35 patients within 13 hours following severe head injury. There was a good correlation between total CK and CK-BB activities in CSF only. The values found in the CSF appear to be a quantitative index of brain dysfunction at admission, and did not correlate with intracranial pressure activity. High levels of CK-BB in the CSF correlated with a poor outcome, and thus offer a reliable criterion for the assessment of the severity of head injury.
http://hdl.handle.net/2268/34843
10.3171/jns.1983.58.5.0689

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