[en] Serum urea and creatinine concentrations were determined in 150 healthy subjects. The formula of Cockcroft and Gault was used in order to calculate creatinine clearance. Such estimation of creatinine clearance is widely used as a parameter for individualization of dosage of drugs secreted primary via the kidneys. The effects of age and sex were then assessed on serum urea, serum creatinine and on creatinine clearance.
Disciplines :
Laboratory medicine & medical technology
Author, co-author :
El Allaf, Dia ; Centre Hospitalier Universitaire de Liège - CHU > Cardiologie
Marchal, C.
El Allaf, M.
Chapelle, Jean-Paul ; Université de Liège - ULiège > Département de pharmacie > Chimie médicale
Deleixhe, A.
Carlier, J.
Language :
French
Title :
Evolution, en fonction de l'age et du sexe, de l'uree, de la creatinine et de la clairance de la creatinine.
Alternative titles :
[en] Development of urea, creatinine and creatinine clearance as a function of age and sex
Publication date :
1984
Journal title :
Archives Internationales de Physiologie et de Biochimie