The Ovine Callipyge Locus: A Paradigm Illustrating the Importance of Non-Mendelian Genetics in Livestock

Georges, Michel; Cockett, N.

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The Ovine Callipyge Locus: A Paradigm Illustrating the Importance of Non-Mendelian Genetics in Livestock

Georges, Michel; Cockett, N.

1996 • In Reproduction Nutrition Development, 36 (6), p. 651-7

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https://hdl.handle.net/2268/34400

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9021876

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Abstract :

[en] An inheritable muscular hypertrophy was recently described in sheep and shown to be determined by the callipyge (CLPG) gene mapped to ovine chromosome 18. We demonstrate in this work that the callipyge phenotype is characterized by a non-Mendelian inheritance pattern, referred to as polar overdominance, in which only heterozygous individuals having inherited the CLPG mutation from their sire express the phenotype. The possible role of parental imprinting in the determinism of polar overdominance is envisaged.

Disciplines :

Veterinary medicine & animal health

Author, co-author :

Georges, Michel ; Université de Liège - ULiège > Département de productions animales > Génomique animale

Cockett, N.

Language :

English

Title :

The Ovine Callipyge Locus: A Paradigm Illustrating the Importance of Non-Mendelian Genetics in Livestock

Publication date :

1996

Journal title :

Reproduction Nutrition Development

ISSN :

0926-5287

eISSN :

1297-9708

Publisher :

EDP Sciences, France

Volume :

Issue :

Pages :

651-7

Available on ORBi :

since 04 January 2010

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