The Ovine Callipyge Locus: A Paradigm Illustrating the Importance of Non-Mendelian Genetics in Livestock

Georges, Michel; Cockett, N.

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The Ovine Callipyge Locus: A Paradigm Illustrating the Importance of Non-Mendelian Genetics in Livestock

Georges, Michel; Cockett, N.

1996 • In Reproduction Nutrition Development, 36 (6), p. 651-7

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https://hdl.handle.net/2268/34400

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9021876

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Abstract :

[en] An inheritable muscular hypertrophy was recently described in sheep and shown to be determined by the callipyge (CLPG) gene mapped to ovine chromosome 18. We demonstrate in this work that the callipyge phenotype is characterized by a non-Mendelian inheritance pattern, referred to as polar overdominance, in which only heterozygous individuals having inherited the CLPG mutation from their sire express the phenotype. The possible role of parental imprinting in the determinism of polar overdominance is envisaged.

Disciplines :

Veterinary medicine & animal health

Author, co-author :

Georges, Michel ; Université de Liège - ULiège > Département de productions animales > Génomique animale

Cockett, N.

Language :

English

Title :

The Ovine Callipyge Locus: A Paradigm Illustrating the Importance of Non-Mendelian Genetics in Livestock

Publication date :

1996

Journal title :

Reproduction Nutrition Development

ISSN :

0926-5287

eISSN :

1297-9708

Publisher :

EDP Sciences, France

Volume :

Issue :

Pages :

651-7

Available on ORBi :

since 04 January 2010

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Bibliography

Allen, N.D., Morris, M.L., Surani, M.A., Epigenetjc control of transgene expression and imprinting by genotype specific modifiers (1990) Cell, 61, pp. 853-861
Baidacci, P.A., Richoux, V., Renard, J.P., Guénet, J.L., Babinet, C., The locus Om, responsible for the DDK syndrome, maps dose to Sigje on mouse chromosome 11 (1992) Mammalian Genome, 2, pp. 100-105
Beechey, C.V., Cattanach, B.M., Viable tertiary trisomy and monosomy within the distal chromosome 12 imprinting region (1994) Mouse Genome, 92, pp. 505-506
Bregliano, J.C., Kidwell, M.G., (1983) Mobile Genetic Elements, pp. 363-410. , (JA Shapiro, ed), Academic Press, New York
Cattanach, B.M., Raspberry, C., Evidence for imprinting involving the distal region of chromosome 12 (1993) Mouse Genome, 91, p. 858
Cockett, N.E., Jackson, S.P., Shay, T.D., Nielsen, D., Green, R.D., Georges, M., Chromosomal localization of the callipyge gene in sheep (Ovis aries) using bovine DNA markers (1994) Proc Natl Acad Sci, USA, 91, pp. 3019-3023
Cockett, N.E., Jackson, S.P., Shay, T.D., Farnir, F., Berghmans, S., Snowder, G., Nielsen, D., Georges, M., Polar overdominance at the ovine callipyge locus (1996) Science, 273, pp. 236-238
Efstratiadis, A., Parental imprinting of autosomal mammalian genes (1994) Curr Opin Genet Dev, 4, pp. 265-280
Forejt, J., Gregorova, S., Genetic analysis of genomic imprinting: An Imprintor 1 gene controls inactivation of the paternal copy of the mouse Tme locus (1992) Cell, 70, pp. 443-450
Georges, M., Andersson, L., Livestock genomics comes of age (1996) Genome Res, , in press
Jackson, S.P., Green, R.D., Muscle trait inheritance, growth performance and feed efficiency of sheep exhibiting a muscle hypertropy phenotype (1993) Proc Western Sec Am Soc Anim Sci, 44, pp. 364-366
Jackson, S.P., Miller, M.F., Green, R.D., Brdecko, K.S., Carcass characteristics of Rambouillet ram lambs with genetic muscular hypertrophy (1993) Proc Western Sec Am Soc Anim Sci, 44, pp. 167-169
Jackson, S.P., Miller, M.F., Green, R.D., The effect of a muscle hypertrophy gene on muscle weights of ram lambs (1993) Proc Western Sec American Soc Anim Sci, 44, pp. 169-196
Moore, T., Haig, D., Genomic imprinting in mammalian development: A parental tug-of-war (1991) Trends Gen, 7, pp. 45-49
Sapienza, C., Sex linked dosage sensitive modifiers as imprinting genes (1990) Development, (SUPPL.), pp. 107-113
Sapienza, C., Paquette, J., Tran, T.H., Peterson, A., Epigenetic and genetic factors affect transgene methylation imprinting (1989) Development, 107, pp. 165-168
Sapienza, C., Paquette, J., Pannunzio, P., Albrechtson, S., Morgan, K., The polar-lethal ovum mutant gene maps to the distal portion of mouse chromosome 11 (1992) Genetics, 132, pp. 241-246
Tartof, K.D., Henikoff, S., Trans-sensing effects from Drosophila to humans (1991) Cell, 65, pp. 201-203
Temple, I.K., Cockwell, A., Hassold, T., Pettay, D., Jacobs, P., Maternal uniparental disomy for chromosome 14 (1991) J Med Genet, 28, pp. 511-514
Wakasugi, N.A., Genetically determined incompatibility system between spermatozoa and eggs leading to embryonic death in mice (1974) J Reprod Fert, 41, pp. 85-96
Wang, J.C.C., Passage, M.B., Yen, P.H., Shapiro, L.J., Mohandas, T.K., Uniparental heterodisomy for chromosome 14 in a phenotypically abnormal familial balanced 13/14 robertsonian translocation carrier (1991) Am J Hum Genet, 48, pp. 1069-1074