Article (Scientific journals)
A narrative review and expert consensus on barriers, facilitators, and research gaps to healthy and positive ageing - Position of the Multidisciplinary International Positive Ageing Group (MIPAG).
Henrotin, Yves; Duque, Sofia; Diraçoglu, Demirhan et al.
2025In Ageing Research Reviews, 112, p. 102847
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Keywords :
Healthy ageing; Integrative medicine; Interdisciplinary care; Interprofessional care; Positive ageing; Preventive medicine; Humans; Consensus; Evidence Gaps; Healthy Aging/psychology; Healthy Aging/physiology; Aging/psychology; Aging/physiology; Aging; Healthy Aging; Biotechnology; Biochemistry; Molecular Biology; Neurology
Abstract :
[en] Recent developments in healthcare and scientific research have shifted the perception of ageing from a period of decline to recognising its potential for sustained functional ability, well-being, and societal contributions. In light of this perspective, a multidisciplinary panel of experts from five European countries conducted a narrative review of the literature. It convened for a one-day consensus meeting to identify key barriers, facilitators, and research priorities related to healthy ageing. Thus, this paper aims to (1) define the concept of positive ageing, (2) discuss barriers and facilitators to healthy ageing, (3) examine the role of healthcare professionals in maintaining and improving intrinsic capacity, and (4) propose a research agenda to address gaps in healthy ageing. The panel identified 70 barriers and 64 facilitators, structured within the WHO's ICOPE framework, related to intrinsic capacity. Twenty-six interventions across five domains-locomotor, sensory, psychological, cognitive capacities, and vitality- were proposed, aimed at both frail and robust individuals, focusing on social integration, psychological well-being, physiological resilience, deficit management, and disorder prevention. The panel also outlined a research agenda emphasising AI-driven ageing support, improved communication strategies, early frailty detection, and the development of locally adapted guidelines and infrastructure for healthy and positive ageing. This framework emphasizes the importance of early-life interventions and advocates for a preventive, holistic, and multidisciplinary approach to aging. In conclusion, the MIPAG's fosters a proactive mindset and early interventions throughout life to prevent the decline and optimise intrinsic capacity.
Disciplines :
Human health sciences: Multidisciplinary, general & others
Author, co-author :
Henrotin, Yves  ;  Université de Liège - ULiège > Département des Sciences de l'activité physique et de la réadaptation > Pathologie générale et physiopathologie - Techniques particulières de kinésithérapie
Duque, Sofia;  Preventive Medicine and Public Health Institute, Faculty of Medicine, University of Lisbon, Hospital Cuf Descobertas, Lisbon, Portugal
Diraçoglu, Demirhan;  Department of Physical Medicine and Rehabilitation, Istanbul Faculty of Medicine, Istanbul University, Istanbul, Turkey
Franco, Gianni ;  Université de Liège - ULiège > Département des sciences cliniques
Briganti, Giovanni  ;  Université de Liège - ULiège > Département des sciences cliniques > Santé digitale ; Service de Médecine computationnelle et neuropsychiatrie, Faculté de Médecine, Pharmacie et Sciences Biomédicales, Université de Mons, Avenue du Champ de Mars 6, Mons 7000, Belgium
Longe, Sarah;  General Practician, Geriatrics Medicine, Integrative Medicine, 2 place Jean Zay, La Rochelle 17000, France
Piotrowicz, Karolina;  Department of Internal Medicine and Gerontology, Jagiellonian University Medical College, Kraków, Poland
Jentoft, Alfonso Jose Cruz;  Servicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain
Cederholm, Tommy;  Clinical Nutrition and Metabolism, Dept of Public Care and Caring Sciences, Uppsala University, Uppsala, Sweden, Theme Inflammation & Ageing, Karolinska University Hospital, Stockholm, Sweden
Ortiz, Luis Agüera;  Department of Psychiatry. Instituto de Investigación Sanitaria (imas12), Hospital Universitario 12 de Octubre, & Centro de Investigación Biomédica en Red de Salud Mental, CIBERSAM, Instituto de Salud Carlos III. Madrid, Spain
Language :
English
Title :
A narrative review and expert consensus on barriers, facilitators, and research gaps to healthy and positive ageing - Position of the Multidisciplinary International Positive Ageing Group (MIPAG).
Publication date :
December 2025
Journal title :
Ageing Research Reviews
ISSN :
1568-1637
eISSN :
1872-9649
Publisher :
Elsevier Ireland Ltd, England
Volume :
112
Pages :
102847
Peer reviewed :
Peer Reviewed verified by ORBi
Funding text :
This work was supported by Laboratoires Expanscience , Paris, France.
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