[en] (1) Background: Ultrasonography of major vessels helps evaluate fluid status and responsiveness in critical human and canine patients. Aims: transrectal and inguinal ultrasonography of caudal vena cava (CVC), aorta (Ao), and femoral artery (FA) and vein (FV) in horses; calculate CVC collapsibility index (CI CVC) and vein-to-artery ratios; compare B- and M-mode; and evaluate repeatability and reproducibility. (2) Methods: B-mode and M-mode video loops were recorded twice by transrectal (Ao, CVC) and inguinal ultrasonography (FV, FA) by two operators on 17 healthy, sedated adult horses. Diameters and areas were measured. CI CVC, CVC-to-Ao ratio (CVC/Ao), FV-to-FA ratio (FV/FA), reproducibility, and repeatability were calculated. (3) Results: Vessels were successfully visualized (mean time: rectal 4 min, inguinal 3 min). CVC displayed respiratory-related dimension changes. Ratios included CI CVC (mean diameter B-mode 30 ± 13%, M-mode 33 ± 12%; area 36 ± 15%), CVC/Ao (mean diameter B-mode 0.43 ± 0.15, M-mode 0.43 ± 0.11; median area 0.56, IQR 0.53-0.64), and FV/FA (mean diameter 3.80 ± 1.02; median area 26.74, IQR 25.23-32.40). M-mode was inadequate for inguinal analysis. B-mode and M-mode measurements did not differ significantly. Repeatability and reproducibility were excellent (transrectal ratios 93.9% and 94.4%, respectively); FV/FA 96.9%. (4) Conclusions: Assessment of CI CVC, CVC/Ao, and FV/FA is feasible, highly repeatable, and reproducible.
Gommeren, Kris ; Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH) > FARAH: Médecine vétérinaire comparée
Saegerman, Claude ; Université de Liège - ULiège > Département des maladies infectieuses et parasitaires (DMI) > Epidémiologie et analyse des risques appliqués aux sciences vétérinaires
van Galen, Gaby ; Sydney School of Veterinary Science, University of Sydney, Sydney, NSW 2006, Australia ; Goulburn Valley Equine Hospital, Congupna, VIC 3633, Australia
Language :
English
Title :
Ultrasonographic Assessment of Caudal Vena Cava Collapsibility Index, Caudal Vena Cava-to-Aorta, and Femoral Vein-to-Artery Ratios in Healthy Sedated Adult Horses.
Publication date :
28 September 2025
Journal title :
Animals : an open access journal from MDPI
ISSN :
2076-2615
eISSN :
2076-2615
Publisher :
Multidisciplinary Digital Publishing Institute (MDPI), Switzerland
Elisa Scala and Inge Durie are affiliated with Evidensia Str\u00F6msholm Referral Equine Hospital, and Gaby van Galen is affiliated with Goulburn Valley Equine Hospital. This study was supported by funding from IVC Evidensia and Stiftelsen Str\u00F6msholm Djursjukv\u00E5rd. The other authors have no competing interests.
Reed S.M. Bayly W.M. Sellon D.C. Cardiovascular Critical Care Equine Internal Medicine 4th ed. Elsevier Amsterdam, The Netherlands 2018 173 174
Crabtree N.E. Epstein K.L. Current Concepts in Fluid Therapy in Horses Front. Vet. Sci. 2021 8 648774 10.3389/fvets.2021.648774 33855057
Henderson I.S.F. Diagnostic and prognostic use of L-lactate measurement in equine practice Equine Vet. Educ. 2013 25 468 475 10.1111/eve.12033
Pachtinger G.E. Drobatz K. Assessment and Treatment of Hypovolemic States Vet. Clin. N. Am. Small Anim. Pract. 2008 38 629 643 10.1016/j.cvsm.2008.01.009
Boysen S.R. Gommeren K. Assessment of Volume Status and Fluid Responsiveness in Small Animals Front. Vet. Sci. 2021 8 630643 10.3389/fvets.2021.630643
Donati P.A. Guevara J.M. Ardiles V. Guillemi E.C. Londoño L. Dubin A. Caudal vena cava collapsibility index as a tool to predict fluid responsiveness in dogs J. Vet. Emerg. Crit. Care 2020 30 677 686 10.1111/vec.13009 33063922
Argaiz E.R. Koratala A. Reisinger N. Comprehensive Assessment of Fluid Status by Point-of-Care Ultrasonography Kidney360 2021 2 1326 1338 10.34067/KID.0006482020
Kearney D. Reisinger N. Lohani S. Integrative Volume Status Assessment POCUS J. 2022 7 65 77 10.24908/pocus.v7iKidney.15023
Di Nicolò P. Tavazzi G. Nannoni L. Corradi F. Inferior Vena Cava Ultrasonography for Volume Status Evaluation: An Intriguing Promise Never Fulfilled J. Clin. Med. 2023 12 2217 10.3390/jcm12062217
Rahman N.H.N. Ahmad R. Kareem M.M. Mohammed M.I. Ultrasonographic assessment of inferior vena cava/abdominal aorta diameter index: A new approach of assessing hypovolemic shock class 1 Int. J. Emerg. Med. 2016 9 8 10.1186/s12245-016-0101-z
Ma Z. Gai J. Sun Y. Bai Y. Cai H. Wu L. Sun L. Liu J. Xue L. Liu B. Measuring the ratio of femoral vein diameter to femoral artery diameter by ultrasound to estimate volume status BMC Cardiovasc. Disord. 2021 21 506 10.1186/s12872-021-02309-7 34670503
Bayraktar M. Kaçmaz M. Correlation of internal jugular vein, common carotid artery, femoral artery and femoral vein diameters with central venous pressure Medicine 2022 101 E31207 10.1097/MD.0000000000031207
Darnis E. Boysen S. Merveille A.C. Desquilbet L. Chalhoub S. Gommeren K. Establishment of reference values of the caudal vena cava by fast-ultrasonography through different views in healthy dogs J. Vet. Intern. Med. 2018 32 1308 1318 10.1111/jvim.15136 29749656
Darnis E. Merveille A.C. Desquilbet L. Boysen S. Gommeren K. Interobserver agreement between non-cardiologist veterinarians and a cardiologist after a 6-hour training course for echographic evaluation of basic echocardiographic parameters and caudal vena cava diameter in 15 healthy Beagles J. Vet. Emerg. Crit. Care 2019 29 495 504 10.1111/vec.12883
Rabozzi R. Oricco S. Meneghini C. Bucci M. Franci P. Evaluation of the caudal vena cava diameter to abdominal aortic diameter ratio and the caudal vena cava respiratory collapsibility for predicting fluid responsiveness in a heterogeneous population of hospitalized conscious dogs J. Vet. Med. Sci. 2020 82 337 344 10.1292/jvms.19-0028
Fujioka T. Nakamura K. Minamoto T. Tsuzuki N. Yamaguchi J. Hidaka Y. Ultrasonographic evaluation of the caudal vena cava in dogs with right-sided heart disease J. Vet. Cardiol. 2021 34 80 92 10.1016/j.jvc.2021.01.005
Barthélemy A. Combet-Curt J. Dupanloup A. Gillet B. Cambournac M. Bonnet-Garin J.-M. Goy-Thollot I. Pouzot-Nevoret C. Establishment of Reference Intervals for Caudal Vena Cava-to-Aorta Ratio Measured Ultrasonographically in Healthy Nonsedated Dogs Top. Companion Anim. Med. 2023 56–57 100822 10.1016/j.tcam.2023.100822
Tuplin M.C. Romero A.E. Boysen S.R. Influence of the Respiratory Cycle on Caudal Vena Cava Diameter Measured by Sonography in Healthy Foals: A Pilot Study J. Vet. Intern. Med. 2017 31 1556 1562 10.1111/jvim.14793
Casalta H. Busoni V. Eppe J. Grulke S. Merveille A.-C. Moula N. Gommeren K. Ultrasonographical Assessment of Caudal Vena Cava Size through Different Views in Healthy Calves: A Pilot Study Vet. Sci. 2022 9 308 10.3390/vetsci9070308 35878325
Del Prete C. Freccero F. Lanci A. Hallowell G.D. Bullone C. Castagnetti C. Pasolini M.P. Transabdominal ultrasonographic measurement of caudal vena cava to aorta derived ratios in clinically healthy neonatal foals Vet. Med. Sci. 2021 7 1451 1459 10.1002/vms3.506 33939323
Marshall K.A. Thomovsky E.J. Brooks A.C. Johnson P.A. Kin Lim C. Gan Heng H. Article Ultrasound measurements of the caudal vena cava before and after blood donation in 9 greyhound dogs Can. Vet. J. 2018 59 973 980
Cambournac M. Goy-Thollot I. Violé A. Boisvineau C. Pouzot-Nevoret C. Barthélemy A. Sonographic assessment of volaemia: Development and validation of a new method in dogs J. Small Anim. Pract. 2018 59 174 182 10.1111/jsap.12759
Kwak J. Yoon H. Kim J. Kim M. Eom K. Ultrasonographic measurement of caudal vena cava to aorta ratios for determination of volume depletion in normal beagle dogs Vet. Radiol. Ultrasound 2018 59 203 211 10.1111/vru.12566
Balıkçı C. Gülersoy E. Şahan A. Günal I. Efficacy of ultrasonographic caudal vena cava to aorta ratios for quantifying canine parvoviral enteritis rehydration Vet. Radiol. Ultrasound 2023 64 930 935 10.1111/vru.13276
Combet-Curt J. Pouzot-Nevoret C. Cambournac M. Magnin M. Nectoux A. Bonnet-Garin J.M. Goy-Thollot I. Barthélemy A. Ultrasonographic measurement of caudal vena cava to aorta ratio during fluid resuscitation of dogs with spontaneous circulatory shock J. Small Anim. Pract. 2023 64 669 679 10.1111/jsap.13654
Meneghini C. Rabozzi R. Franci P. Correlation of the ratio of caudal vena cava diameter and aorta diameter with systolic pressure variation in anesthetized dogs Am. J. Vet. Res. 2016 77 137 143 10.2460/ajvr.77.2.137
Henneke D.R. Potter G.D. Kreider J.L. Yeates B.F. Relationship between condition score, physical measurements and body fat percentage in mares Equine Vet. J. 1983 15 371 372 10.1111/j.2042-3306.1983.tb01826.x
Moore J. Barton M. White N. Buchanan F. Melton T. Jackson J. Gilleland B. Smith M. Lockerman K. The Glass Horse Equine Colic The University of Georgia Athens, GA, USA 2007
Denoix J.M. Ventral aspect of the equine pelvis: Vessels and nerves Essentials of Clinical Anatomy of the Equine Locomotor System 1st ed. CRC Press Boca Raton, FL, USA 2019 182
Watson P.F. Petrie A. Method agreement analysis: A review of correct methodology Theriogenology 2010 73 1167 1179 10.1016/j.theriogenology.2010.01.003 20138353
Hoffman A.M. Airway Physiology and Clinical Function Testing Vet. Clin. N. Am. Small Anim. Pract. 2007 37 829 843 10.1016/j.cvsm.2007.05.013 17693201
Holland M. Hudson J. Bao Y. Gaillard P. Aortic to caudal vena cava ratio measurements using abdominal ultrasound are increased in dogs with confirmed systemic hypertension Vet. Radiol. Ultrasound 2020 61 206 214 10.1111/vru.12822 31845468
Kaminecki I. Huang D.M. Shipman P.C. Gibson R.W. Point-of-Care Ultrasonography for the Assessment of Dehydration in Children A Systematic Review Pediatr. Emerg. Care 2023 39 786 796 10.1097/PEC.0000000000003025
Mannarino S. Bulzomì P. Codazzi A.C. Rispoli G.A. Tinelli C. De Silvestri A. Manzoni F. Chiapedi S. Inferior vena cava, abdominal aorta, and IVC-to-aorta ratio in healthy Caucasian children: Ultrasound Z-scores according to BSA and age J. Cardiol. 2019 74 388 393 10.1016/j.jjcc.2019.02.021 30952562
Fielding C.L. Magdesian K.G. Edman J.E. Determination of body water compartments in neonatal foals by use of indicator dilution techniques and multifrequency bioelectrical impedance analysis Am. J. Vet. Res. 2011 72 1390 1396 10.2460/ajvr.72.10.1390
Cardillo J.H. Zersen K.M. Cavanagh A.A. Point of care ultrasound measurement of paralumbar caudal vena cava diameter and caudal vena cava to aortic ratio in hypovolemic dogs Front. Vet. Sci. 2024 11 1467043 10.3389/fvets.2024.1467043
Oh J.H. Noninvasive and simple, but accurate? Meta-analysis of evidence-based point-of-care ultrasound for assessing dehydration in children Clin. Exp. Pediatr. 2023 66 475 10.3345/cep.2023.00745
Mele D. Pedini I. Alboni P. Levine R.A. Anatomic M-mode: A new technique for quantitative assessment of left ventricular size and function Am. J. Cardiol. 1998 81 82G 85G 10.1016/S0002-9149(98)00060-5
American College of Emergency Physicians Emergency ultrasound guidelines Ann. Emerg. Med. 2009 53 550 570 10.1016/j.annemergmed.2008.12.013 19303521
Bartlett J.W. Frost C. Reliability, repeatability and reproducibility: Analysis of measurement errors in continuous variables Ultrasound Obstet. Gynecol. 2008 31 466 475 10.1002/uog.5256 18306169
Muir W.W. Hubbell J.A.E. Equine Anesthesia: Monitoring and Emergency Therapy 2nd ed. Saunders Philadelphia, PA, USA 2014
Yamashita K. Tsubakishita S. Futaoka S. Ueda I. Hamaguchi H. Seno T. Katoh S. Izumisawa Y. Kotani T. Muir W.W. Cardiovascular Effects of Medetomidine, Detomidine and Xylazine in Horses J. Vet. Med. Sci. 2000 62 1025 1032 10.1292/jvms.62.1025
Herreria-Bustillo V.J. Fitzgerald E. Humm K.R. Caval-aortic ratio and caudal vena cava diameter in dogs before and after blood donation J. Vet. Emerg. Crit. Care 2019 29 643 646 10.1111/vec.12900