Article (Scientific journals)
Gynecologic surgery for benign disease: Preserving reproductive potential.
Tulandi, Togas; Mocanu, Edgar; Purandare, Nikhil et al.
2025In International Journal of Gynecology and Obstetrics
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Keywords :
FIGO; benign gynecologic surgery; fertility‐sparing surgery; infertility; reproductive function; reproductive surgery; Obstetrics and Gynecology
Abstract :
[en] Preserving fertility is essential when managing benign gynecologic disorders in reproductive-aged women. Surgical interventions can impact future fertility, therefore requiring an evidence-based, individualized approach. The FIGO Committee on Reproductive Endocrinology and Infertility reviewed current literature to develop recommendations for fertility-sparing surgical management. Effective treatment must balance disease control with fertility preservation. Evidence supports refined surgical techniques and alternative methods that minimize reproductive harm. In pregnancy loss management, medical treatment is preferred; however, if surgery is needed, hysteroscopic evacuation is safer than sharp curettage, reducing the risk of intrauterine adhesions. Similarly for other operative hysteroscopic procedures or abdominal procedures, including myomectomy, the use of an adhesion-reducing substance is recommended. During abdominal myomectomy, only symptomatic or fertility-impairing fibroids should be removed, as excessive resection may reduce pregnancy chances. In endometrioma surgery, preserving ovarian tissue is crucial by minimizing stripping of the pseudocapsule, or using sclerotherapy may help. Oocyte cryopreservation should be discussed when recurrence or reduced ovarian reserve is a concern. Hydrosalpinx often requires salpingectomy to enhance in vitro fertilization outcomes, but surgeons should protect ovarian blood flow by minimizing thermal injury. For adenomyosis, medical management is preferred due to the risks associated with surgical techniques like the triple-flap procedure. In polycystic ovary syndrome, laparoscopic ovarian drilling is discouraged; ovulation induction with letrozole or gonadotropins is safer and effective. In summary, fertility-sparing treatment demands personalized, evidence-based strategies that prioritize reproductive potential while managing disease. As reproductive goals evolve, continued refinement of these approaches remains vital to women's health care.
Disciplines :
Reproductive medicine (gynecology, andrology, obstetrics)
Author, co-author :
Tulandi, Togas ;  Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada
Mocanu, Edgar;  Rotunda Hospital, Dublin, Ireland ; Royal College of Surgeons in Ireland, Dublin, Ireland
Purandare, Nikhil;  Department of Obstetrics and Gynaecology, Galway University Hospital, Galway, Ireland
Nelson, Scott M;  School of Medicine, Dentistry and Nursing, University of Glasgow, Glasgow, UK
Barnea, Eytan R;  University of Miami Miller School of Medicine, New York, New York, USA
Dolmo Carluccio, Ruth;  Department of Obstetrics, Gynecology and Reproductive Sciences, University of Miami Miller School of Medicine, Miami, Florida, USA
Topcu, Elif Goknur;  Sisli Kolan International Hospital, Istanbul, Turkey
Feldberg, Dov;  Helen Schneider Hospital for Women, Rabin Medical Center, Petah Tikva, Israel ; Tel Aviv University School of Medicine, Tel Aviv, Israel
FIGO Committee on Reproductive Endocrinology and Infertility
Other collaborator :
Henry, Laurie  ;  Université de Liège - ULiège > Département des sciences cliniques ; Centre Hospitalier Universitaire de Liège - CHU > > Service de gynécologie-obstétrique (CHR)
Language :
English
Title :
Gynecologic surgery for benign disease: Preserving reproductive potential.
Publication date :
24 September 2025
Journal title :
International Journal of Gynecology and Obstetrics
ISSN :
0020-7292
eISSN :
1879-3479
Publisher :
John Wiley and Sons Ltd, United States
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 07 November 2025

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