Domestic animal milk; Heat treatment; Human milk; LC-ESI-MS/MS; Milk oligosaccharides (MOs); Oligosaccharides; Cattle; Animals; Female; Sheep; Humans; Hot Temperature; Milk, Human; Mammals; Milk; Tandem Mass Spectrometry/methods; Composition patterns; Domestic animals; Label free; Lc ms/ms(ESI); LC/ESI-MS/MS; Mammal species; Milk oligosaccharide; Tandem Mass Spectrometry; Analytical Chemistry; Food Science
Abstract :
[en] Milk oligosaccharides (MOs) exhibit significant variations in concentrations and patterns among different species. However, there is limited knowledge about milk oligosaccharides in domestic animals and the impact of heat treatment on them. Here, we developed an LC-ESI-MS/MS method to analyze 11 milk oligosaccharides in 7 distinct species simultaneously. The results showed that human milk presented a completely different composition pattern of milk oligosaccharides from animals. In detail, animal milk predominantly contained sialylated oligosaccharides, and human milk had high levels of fucosylated neutral oligosaccharides. Notably, sheep milk exhibited similarities to human milk in terms of oligosaccharides composition. Then, the milk samples from dairy cows were treated with two common industrial heat treatments. We found that 65 °C treatment had no significant effect on the concentration of milk oligosaccharides, whereas 135 °C heating was associated with their decline, suggesting that high temperatures should be avoided in the processing of oligosaccharides supplemented/enriched products.
Disciplines :
Microbiology
Author, co-author :
Yao, Qianqian; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China, Department of Food Science, Faculty of Veterinary Medicine, University of Liège, Liège, Belgium
Gao, Yanan; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China
Wang, Fengen; Institute of Quality Standard and Testing Technology for Agro-Products, Shandong Academy of Agricultural Sciences, Jinan 250100, PR China
Delcenserie, Véronique ; Université de Liège - ULiège > Département de sciences des denrées alimentaires (DDA) > Gestion de la qualité dans la chaîne alimentaire
Wang, Jiaqi; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China
Zheng, Nan; State Key Laboratory of Animal Nutrition, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, Beijing 100193, PR China. Electronic address: zhengnan@caas.cn
Language :
English
Title :
Label-Free quantitation of milk oligosaccharides from different mammal species and heat treatment influence.
This study was supported by grants from the National Key R&D Program of China (2022YFD1600104), National Key R&D Program of China (2022YFD1600103), the Ministry of Modern Agro-Industry Technology Research System of China (CARS-36).
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