[en] The bacterium Treponema pallidum pertenue causes yaws in humans and nonhuman primates. We describe 33% T. pallidum pertenue seropositivity in 9 species of nonhuman primates in Uganda and Rwanda, seroconversion during a lethal outbreak and a novel bacterial genomic lineage. Yaws may threaten both public health and conservation in the region.
Disciplines :
Microbiology
Author, co-author :
Goldberg, Tony L; University of Wisconsin–Madison, Madison, United States
Owens, Leah A; University of Wisconsin–Madison, Madison, United States
Nziza, Julius; Gorilla Doctors, Musanze, Rwanda
Muvunyi, Richard ; Université de Liège - ULiège > TERRA Research Centre ; Rwanda Development Board, Kigali, Rwanda
Rothman, Jessica M; Hunter College of City, University of New York, New York, United States ; New York Consortium in Evolutionary Primatology, New York, United States
Chapman, Colin A; Vancouver Island University, Nanaimo, Canada
Language :
English
Title :
Yaws Circulating in Nonhuman Primates, Uganda and Rwanda.
Publication date :
April 2025
Journal title :
Emerging Infectious Diseases
ISSN :
1080-6040
eISSN :
1080-6059
Publisher :
Centers for Disease Control and Prevention (CDC), United States
Volume :
31
Issue :
4
Pages :
799 - 803
Peer reviewed :
Peer Reviewed verified by ORBi
Funding text :
We thank the Uganda Wildlife Authority, the Uganda National Council for Science and Technology, and the Rwanda Development Board for granting permission to conduct this research. We thank David Hyeroba and the staff of the Kibale EcoHealth Project and the Kibale Fish and Monkey Project for assistance with fieldwork, and Makerere University Biological Field Station for logistic support. We thank Fabian Leendertz, Sebastien Calvignac-Spencer, and Jan Gogarten for generously providing guidance about target capture sequencing, Sascha Knauf for helpful advice about serologic methods, and Christopher Dunn for assisting with DNA This research was funded by National Institutes of Health (grant no. TW009237) as part of the joint National Institutes of Health\u2013National Science Foundation Ecology of Infectious Disease program and the UK Economic and Social Research Council (to T.L.G. and C.A.C.) and by the University of Wisconsin\u2013Madison John D. MacArthur Professorship Chair (to T.L.G.).
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