Article (Scientific journals)
A nutritional prognostic model for hospitalized Belgian blue calves: The Calf-CONUT ratio for predicting survival
Eppe, Justine; Van Leeuw, Corine; Borelli, Elena et al.
2025In Preventive Veterinary Medicine, 241, p. 106557
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Keywords :
urea; cholesterol; albumin; cattle; nutritional assessment; prognosis
Abstract :
[en] Malnutrition is a major factor in disease management failure. In humans, the CONUT (COntrolling NUTritional status) score assesses nutritional status based on albumin, cholesterol, and lymphocyte levels (sensitivity 92,30 %; specificity of 85 %). In bovine medicine, few studies focus on calf nutrition status. This study compares serum urea, cholesterol, and albumin levels in Belgian Blue calves between hospital admission and discharge (or death) and between survivors (S) and non-survivors (NS). At admission, cholesterol levels did not significantly differ between groups (p > 0.1). Albumin levels were higher in S (p = 0.02), while urea levels were lower (p = 0.04). At discharge, S showed a significant increase in cholesterol (p < 0.05) and a decrease in urea (p < 0.01) and albumin (p < 0.05). A urea/albumin ratio, named the Calf-CONUT ratio, above 2.64 was associated with increased mortality risk (Relative Risk: 2.29, Odds Ratio: 5.75) but demonstrated low sensitivity (46 %) and high specificity (87 %), suggesting limited standalone predictive power. If the analysis focuses solely on calves suffering from enteritis, the threshold value is 2.85, with improved sensitivity and specificity (Se 83 %; Sp 78 %; relative risk: 10; odd ratio: 15). This study provides initial insights into the nutritional assessment of hospitalized calves and paves the way for innovative approaches to their nutritional and medical management. Further research on specific diseases and breeds is needed to refine these thresholds.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Eppe, Justine  ;  Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH) > FARAH: Productions animales durables
Van Leeuw, Corine ;  Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH) > FARAH: Santé publique vétérinaire
Borelli, Elena;  University of Glasgow > School of Biodiversity, One Health and Veterinary Medicine > Scottish centre for production animal and food safety
Casalta, Hélène  ;  Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH) > FARAH: Productions animales durables
Djebala, Salem;  University college of Dublin > School of veterinary medicine > Farm animal clinic
Rao, Anne-Sophie;  RumeXpert
Théron, Léonard;  RumeXpert
Bayrou, Calixte  ;  Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH) > FARAH: Productions animales durables
Language :
English
Title :
A nutritional prognostic model for hospitalized Belgian blue calves: The Calf-CONUT ratio for predicting survival
Publication date :
07 May 2025
Journal title :
Preventive Veterinary Medicine
ISSN :
0167-5877
eISSN :
1873-1716
Publisher :
Elsevier
Volume :
241
Pages :
106557
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 09 May 2025

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